Fig. 5

LD accumulation impaired cell proliferation. (A) Viability of WT and KO cells treated with or without 300 μM OA for 24 h (n = 4 independent experiments). (B). Viability of KO cells treated with 20 μM C75 or 20 μM AR7 for 24 h (n = 4 independent experiments). (C) Viability of KO cells treated with 10 μM C75 for 24 h (n = 3 independent experiments). (D) LD density of KO cells treated with 10 μM C75 for 24 h. The data are expressed as the mean ± SD; *p < 0.05, ** p < 0.01, *** p < 0.001