Table 1 Characteristics of all study participants and by FLI
| Â | Total | Â | Normal FLI | Â | Indeterminate FLI | Â | Severely increased FLI | Â | Â |
|---|---|---|---|---|---|---|---|---|---|
|  | n = 689 |  | n = 215 |  | n = 145 |  | n = 329 |  |  |
Characteristics | Median (25th—75th percentile) |  |  |  |  |  |  |  | p-value |
Age [years] | 63 | (58; 68) | 61 | (57; 67) | 64 | (59; 68) | 64 | (59; 68) | 0.001 |
BMI [kg/m2] | 27.4 | (24.1; 30.7) | 23.2 | (21.7; 24.9) | 25.8 | (24.7; 27.8) | 30.9 | (28.7; 33.5) |  < 0.001 |
Waist circumference [cm] | 93.6 | (82.8; 103.0) | 78.2 | (73.8; 84.0) | 89.5 | (85.0; 94.1) | 103.5 | (98.0; 109.5) |  < 0.001 |
HDL [mg/dl] | 63.8 | (51.0; 77.0) | 77.0 | (66.5; 90.8) | 68.0 | (57.1; 78.0) | 53.0 | (45.0; 64.0) |  < 0.001 |
non-HDL [mg/dl] | 146.0 | (121.0; 172.2) | 135.9 | (112.1; 158.1) | 145.1 | (121.0; 177.0) | 152.0 | (124.0; 181.0) |  < 0.001 |
Triglycerides [mg/dl] | 106.0 | (77.0; 145.0) | 74.8 | (61.0; 94.0) | 100.2 | (76.2; 129.0) | 136.0 | (107.0; 179.0) |  < 0.001 |
gGT [U/l] | 24.0 | (17.0; 37.0) | 16.0 | (13.0; 21.0) | 24.0 | (17.0; 32.0) | 32.0 | (23.0; 49.0) |  < 0.001 |
AST [U/l] | 24.0 | (20.0; 28.0) | 22.0 | (19.0; 25.8) | 24.1 | (21.0; 27.6) | 25.0 | (21.0; 30.2) |  < 0.001 |
ALT [U/l] | 24.0 | (18.7; 31.0) | 18.9 | (16.0; 24.0) | 23.4 | (19.8; 29.0) | 29.0 | (23.0; 37.0) |  < 0.001 |
Uric acid [mg/dl] | 5.2 | (4.4; 6.3) | 4.5 | (3.9; 5.1) | 5.3 | (4.4; 5.9) | 6.0 | (5.0; 7.1) |  < 0.001 |
Fasting glucose [mg/dl] | 97 | (92; 105) | 93 | (88; 97) | 96 | (92; 102) | 103 | (96; 112) |  < 0.001 |
FLI | 54.9 | (24.4; 89.4) | 15.3 | (9.4; 22.9) | 41.9 | (35.3; 49.5) | 90.5 | (78.2; 100.2) |  < 0.001 |
| Â | n (%) | Â | |||||||
Sex | |||||||||
 Male | 304 | (44.1) | 46 | (21.4) | 67 | (46.2) | 191 | (58.1) |  < 0.001 |
 Female | 385 | (55.9) | 169 | (78.6) | 78 | (53.8) | 138 | (41.9) |  |
Education [years] | |||||||||
 <  = 12 years | 417 | (60.5) | 114 | (53.0) | 82 | (56.6) | 221 | (67.2) | 0.002 |
 > 12 years | 272 | (39.5) | 101 | (47.0) | 63 | (43.4) | 108 | (32.8) |  |
Physical activity | |||||||||
 >  = 2 h/week | 266 | (38.6) | 107 | (49.8) | 61 | (42.1) | 98 | (29.8) |  < 0.001 |
 1 h/week | 230 | (33.4) | 65 | (30.2) | 53 | (36.6) | 112 | (34.0) |  |
 < 1 h/week | 88 | (12.8) | 20 | (9.3) | 10 | (6.9) | 58 | (17.6) |  |
  (almost) no activity | 105 | (15.2) | 23 | (10.7) | 21 | (14.5) | 61 | (18.5) |  |
Smoking | |||||||||
 Current smoker | 82 | (11.9) | 21 | (9.8) | 15 | (10.3) | 46 | (14.0) | 0.139 |
 Former smoker | 298 | (43.3) | 91 | (42.3) | 56 | (38.6) | 151 | (45.9) |  |
 Never smoker | 309 | (44.8) | 103 | (47.9) | 74 | (51.0) | 132 | (40.1) |  |
Hypertension | |||||||||
 Yes | 313 | (45.4) | 45 | (20.9) | 54 | (37.2) | 214 | (65.0) |  < 0.001 |
 No | 376 | (54.6) | 170 | (79.1) | 91 | (62.8) | 115 | (35.0) |  |
Diabetes | |||||||||
 Yes | 49 | (7.1) | 5 | (2.3) | 5 | (3.4) | 39 | (11.9) |  < 0.001 |
 No | 640 | (92.9) | 210 | (97.7) | 140 | (96.6) | 290 | (88.1) |  |
Metabotype | |||||||||
 1 | 140 | (20.3) | 61 | (28.4) | 24 | (16.6) | 55 | (16.7) | 0.001 |
 2 | 478 | (69.4) | 154 | (71.6) | 112 | (77.2) | 212 | (64.4) |  |
 3 | 71 | (10.3) | (0.0) | (0.0) | 9 | (6.2) | 62 | (18.8) |  |