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Table 2 Serum comparisons in the three groups of pregnant women receiving different doses of LT4 treatment

From: Evaluation of the therapeutic efficacy of different doses of LT4 in pregnant women with high-normal TSH levels and TPOAb positivity in the first half of pregnancy

Parameter

G0 (n = 122)

G25 (n = 69)

G50 (n = 58)

P

FT4 (pmol/L)

12.75(11.50–13.70)

13.70(12.10–14.90) a

14.05(12.68–16.13) b

<0.001

TSH (mIU/L)

3.66(2.45–4.16)

2.37(1.77–2.89) c

2.07(1.55–2.98) d

<0.001

TPOAb (IU/mL)

67.55(37.60-140.25)

82.80(46.80–179.00)

99.25(54.53-200.53)

0.072

TC (mmol/L)

5.91 ± 0.90

5.87 ± 0.82

5.67 ± 0.69

0.210

TG (mmol/L)

3.26 ± 0.94

3.01 ± 0.75

2.97 ± 0.79

0.046

HDL (mmol/L)

2.17 ± 0.44

2.04 ± 0.49

2.08 ± 0.47

0.148

LDL (mmol/L)

4.23 ± 0.81

4.02 ± 0.79

3.93 ± 0.67 e

0.033

  1. Numerical data are exhibited as either the median along with its interquartile range or as the mean along with the standard deviation. a demonstrates P < 0.01 in contrast to the G0 group; b, c, and d indicate P < 0.001 in contrast to the G0 group; e indicates P < 0.05 in comparison to the G0 group. All comparisons were corrected using Bonferroni correction