Skip to main content

Table 2 The correlation between LDLR polymorphisms and serum lipid levels at enrollment

From: Impact of LDLR polymorphisms on lipid levels and atorvastatin’s efficacy in a northern Chinese adult Han cohort with dyslipidemia

rsID

gDNA_coordinate

wild/mutant (patients)

P

TG (wild greater)

TG (mutant greater)

TC (wild greater)

TC (mutant greater)

LDL-C (wild greater)

LDL-C (mutant greater)

HDL-C (wild greater)

HDL-C (mutant greater)

rs1433099

chr19:g.11242658T > C

21/234

0.807

0.193

0.977

0.023

0.981

0.019

0.517

0.483

rs14158

chr19:g.11242044G > A

94/161

0.686

0.314

0.995

0.005

0.992

0.008

0.844

0.156

rs2738466

chr19:g.11,242,765 A > G

94/161

0.686

0.314

0.995

0.005

0.992

0.008

0.844

0.156

rs5742911

chr19:g.11,243,445 A > G

94/161

0.686

0.314

0.995

0.005

0.992

0.008

0.844

0.156

rs17249057

chr19:g.11243502T > C

94/161

0.686

0.314

0.995

0.005

0.992

0.008

0.844

0.156

rs2738467

chr19:g.11,243,735 C > T

182/73

0.467

0.533

0.401

0.599

0.509

0.491

0.727

0.273

rs55971831

chr19:g.11,243,411 C > A

188/67

0.998

0.002

0.386

0.614

0.264

0.736

0.025

0.975

rs751672818

chr19:g.11243411delC

246/9

0.181

0.819

0.331

0.669

0.333

0.667

0.658

0.342

rs7254521

chr19:g.11,243,422 C > T

253/2

0.17

0.83

0.231

0.769

0.165

0.835

0.847

0.153

rs566918949

chr19:g.11243467G > A

253/2

0.422

0.578

0.692

0.308

0.803

0.197

0.401

0.599

rs568219285

chr19:g.11242719G > A

254/1

0.958

0.042

0.955

0.045

0.514

0.486

0.061

0.939

  1. Note Serum lipid levels at enrollment were compared by the Wilcoxon rank sum test. Values in bold are statistically significant (P < 0.05). The P values listed in the table represent the null hypothesis, while the remarks in parentheses are indicative of the alternative hypothesis
Back to article page

Lipids in Health and Disease

ISSN: 1476-511X