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Table 3 Weighted multivariate Cox regression analysis for the association of CVD mortality with PHR and HDL-C

From: The association of the platelet/high-density lipoprotein cholesterol ratio with self-reported stroke and cardiovascular mortality: a population-based observational study

PHR

Model 0

Model 1

Model 2

Model 3

 

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

Per SD increase

1.07(0.93,1.23)

0.33

1.11(1.03,1.19)

0.01

1.10(1.02,1.18)

0.01

1.14(1.06,1.22)

 < 0.001

Per 100 increase

1.07(0.94,1.21)

0.33

1.10(1.03,1.18)

0.01

1.10(1.02,1.17)

0.01

1.13(1.06,1.21)

 < 0.001

HDL-C

Model 0

Model 1

Model 2

Model 3

 

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

Per SD increase

0.86(0.70,1.06)

0.17

0.82(0.65,1.04)

0.10

0.84(0.66,1.06)

0.14

0.83(0.66,1.05)

0.13

Per 1 increase

0.70(0.42,1.16)

0.17

0.63(0.36,1.10)

0.10

0.66(0.38,1.15)

0.14

0.65(0.37,1.13)

0.13

  1. Model 0: Not adjusted
  2. Model 1: Adjusted for age and sex
  3. Model 2: Further adjusted for marital status, smoking, and drinking status based on Model 1
  4. Model 3: Further adjusted for thyroid problems, cancer, CHD, and CKD based on Model 2
  5. Abbreviations: HDL-C High-density lipoprotein cholesterol, PHR Platelet-to-high-density lipoprotein cholesterol ratio, CVD Cardiovascular disease, CHD Coronary heart disease, CKD Chronic kidney disease, SD Standard deviation, HR Hazard ratio, CI Confidence interval