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  1. Research

    Acute changes in blood lipid profiles and metabolic risk factors in collegiate elite taekwondo athletes after short-term de-training: a prospective insight for athletic health management

    This study used a short-term de-training model to mimic the physiological weight changes during the early retirement stage in Taekwondo (TKD) athletes. This study investigates whether the negative changes in b...

    Yu-Chi Sung, Yi-Hung Liao, Chung-Yu Chen, Yu-Liang Chen and Chun-Chung Chou

    Lipids in Health and Disease 2017 16:143

    Published on: 24 July 2017

  2. Research

    Efficacy and safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab and evolocumab, a post-commercialization study

    Efficacy-safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab (ALI) and evolocumab (EVO), have previously been evaluated through controlled clinical trials with selective pati...

    Joshua Choi, Amir M Khan, Michael Jarmin, Naila Goldenberg, Charles J Glueck and Ping Wang

    Lipids in Health and Disease 2017 16:141

    Published on: 24 July 2017

  3. Research

    Visceral fat mass: is it the link between uric acid and diabetes risk?

    Uric acid (UA) has been suggested as a novel risk factor for diabetes. However, its definite role in this prevalent disease is still the subject of much discussion because it is always accompanied with other m...

    Neda Seyed-Sadjadi, Jade Berg, Ayse A. Bilgin and Ross Grant

    Lipids in Health and Disease 2017 16:142

    Published on: 24 July 2017

  4. Research

    Lysophosphatidic acid plasma concentrations in healthy subjects: circadian rhythm and associations with demographic, anthropometric and biochemical parameters

    Lysophosphatidic acid (LPA) is a bioactive lipid with a wide biological activity. Previous studies have shown its potential usefulness as a diagnostic marker for ovarian cancer. The aim of the study was to inv...

    Anna Michalczyk, Marta Budkowska, Barbara Dołęgowska, Dariusz Chlubek and Krzysztof Safranow

    Lipids in Health and Disease 2017 16:140

    Published on: 21 July 2017

  5. Research

    Association between serum osteocalcin and glucose/lipid metabolism in Chinese Han and Uygur populations with type 2 diabetes mellitus in Xinjiang: two cross-sectional studies

    Recent studies have shown osteocalcin (OC) plays an important role in regulating glucose and lipid metabolism. Thus, the aim of this study was to investigate the association of OC with glucose and lipid metabo...

    Yuan Chen, Qiang Zhao, Guoli Du and Yancheng Xu

    Lipids in Health and Disease 2017 16:139

    Published on: 21 July 2017

  6. Research

    15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell

    A great number of studies reported that 12/15-lipoxygenase (12/15-LO) played an important role in atherosclerosis. And its arachidonic acid(AA) metabolite, 15(S)-hydroperoxy-5,8,11,13-(Z,Z,Z,E)-eicosatetraenoi...

    Guohua Ma, Bing Pan, Sufen Ren, Caixia Guo, Yansong Guo, Lixin Wei, Lemin Zheng and Buxing Chen

    Lipids in Health and Disease 2017 16:137

    Published on: 12 July 2017

  7. Research

    Identification and characterization of single nucleotide polymorphism markers in FADS2 gene associated with olive oil fatty acids composition

    Genotyping of the FAD2.1 and FAD2.3 polymorphisms in the fatty acid desaturase 2 gene (FADS2) shows that they are associated with the fatty acids composition of olive oil samples. However, these associations requ...

    Rayda Ben Ayed, Karim Ennouri, Hajer Ben Hlima, Slim Smaoui, Mohsen Hanana, Rim Mzid, Sezai Ercişli and Ahmed Rebai

    Lipids in Health and Disease 2017 16:138

    Published on: 12 July 2017

  8. Research

    Dietary supplementation of α-linolenic acid induced conversion of n-3 LCPUFAs and reduced prostate cancer growth in a mouse model

    α-linolenic acid (ALA) is an n-3 polyunsaturated fatty acid (PUFA) and the substrate for long-chain n-3 PUFAs. The beneficial effects of ALA on chronic diseases are still in dispute, unlike those of eicosapent...

    Jingjing Li, Zhennan Gu, Yong Pan, Shunhe Wang, Haiqin Chen, Hao Zhang, Wei Chen and Yong Q. Chen

    Lipids in Health and Disease 2017 16:136

    Published on: 11 July 2017

  9. Research

    Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

    The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic pla...

    Changpo Lin, Xiao Tang, Lirong Xu, Ruizhe Qian, Zhenyu Shi, Lixin Wang, Tingting Cai, Dong Yan, Weiguo Fu and Daqiao Guo

    Lipids in Health and Disease 2017 16:135

    Published on: 10 July 2017

  10. Research

    Baccaurea angulata fruit juice reduces atherosclerotic lesions in diet-induced Hypercholesterolemic rabbits

    Atherosclerosis is the most common disease of large and medium-sized arteries linked to oxidative stress, dyslipidemia as well as chronic inflammation. The aim of this study was to evaluate the potential healt...

    Muhammad Ibrahim, Idris Adewale Ahmed, Maryam Abimbola Mikail, Afeez Adekunle Ishola, Samsul Draman, Muhammad Lokman Md Isa and Afzan Mat Yusof

    Lipids in Health and Disease 2017 16:134

    Published on: 7 July 2017

  11. Review

    Effects of aerobic exercise on lipids and lipoproteins

    Dyslipidemia is the risk of cardiovascular disease, and their relationship is clear. Lowering serum cholesterol can reduce the risk of coronary heart disease. At present, the main treatment is taking medicine,...

    Yating Wang and Danyan Xu

    Lipids in Health and Disease 2017 16:132

    Published on: 5 July 2017

  12. Research

    Lipid management in India: a nationwide, cross-sectional physician survey

    Current international guidelines on dyslipidemia are not concordant on various aspects of management. Also, there are no uniformly accepted Indian guidelines. We, therefore, performed a physician survey to und...

    Gurpreet S. Wander, Uday M. Jadhav, Amruta Chemburkar, Meena Lopez and Jaideep Gogtay

    Lipids in Health and Disease 2017 16:130

    Published on: 3 July 2017

  13. Research

    Effect of cholecystectomy on hepatic fat accumulation and insulin resistance in non-obese Hispanic patients: a pilot study

    Nonalcoholic fatty liver disease (NAFLD) is highly prevalent worldwide. Experimental studies have shown that cholecystectomy (XGB) increases hepatic fat content in mice and appears associated to NAFLD in large...

    Víctor Cortés, Nicolás Quezada, Sergio Uribe, Marco Arrese and Flavio Nervi

    Lipids in Health and Disease 2017 16:129

    Published on: 30 June 2017

  14. Review

    Lipid Droplets in Health and Disease

    Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found in almost all organisms, from bact...

    Gizem Onal, Ozlem Kutlu, Devrim Gozuacik and Serap Dokmeci Emre

    Lipids in Health and Disease 2017 16:128

    Published on: 29 June 2017

  15. Short report

    Association of BUD13 polymorphisms with metabolic syndrome in Chinese population: a case-control study

    BUD13 homolog (BUD13), one of submits of the retention and splicing complex, was identified in yeast as a splicing factor that affected nuclear pre-mRNA retention. While more and more studies demonstrated that...

    Lili Zhang, Yueyue You, Yanhua Wu, Yangyu Zhang, Mohan Wang, Yan Song, Xinyu Liu and Changgui Kou

    Lipids in Health and Disease 2017 16:127

    Published on: 28 June 2017

  16. Research

    A new use for an old index: preoperative high-density lipoprotein predicts recurrence in patients with hepatocellular carcinoma after curative resections

    Hepatocellular carcinoma has high incidence and mortality worldwide. Liver is the site of most metabolic biotransformation, which could reflect the status of cells. Most plasma apolipoproteins, endogenous lipi...

    Lu Tian, Qian Yu, Xing-Hui Gao, Jiong Wu, Xiao-Lu Ma, Qian Dai, Chun-Yan Zhang, Yan Zhou, Yi-Chi Zhang, Bai-Shen Pan, Jian Zhou, Jia Fan, Xin-Rong Yang and Wei Guo

    Lipids in Health and Disease 2017 16:123

    Published on: 26 June 2017

  17. Research article

    Effect of ezetimibe add-on therapy over 52 weeks extension analysis of prospective randomized trial (RESEARCH study) in type 2 diabetes subjects

    Lowering cholesterol levels decreases the risk of atherosclerotic diseases. Effective ways to stably reduce LDL-C level are warranted in type 2 diabetic patients, a high-risk population for CVD, with various a...

    Kentaro Sakamoto, Mitsunobu Kawamura, Takayuki Watanabe, Keiko Ashidate, Takahide Kohro, Akira Tanaka, Yasumichi Mori, Motoki Tagami, Tsutomu Hirano, Tsutomu Yamazaki and Teruo Shiba

    Lipids in Health and Disease 2017 16:122

    Published on: 24 June 2017

  18. Research

    The association of lipid metabolism relative gene polymorphisms and ischemic stroke in Han and Uighur population of Xinjiang

    The present study is aimed to evaluate difference of lipid metabolism related gene single nucleotide polymorphisms (SNPs) with ischemic stroke (IS) in Han and Uighur population of Xinjiang, China.

    Yun-hua Yue, Ling-yun Liu, Liang Hu, You-mei Li, Jie-ping Mao, Xiao-ying Yang and Na-mu Dila

    Lipids in Health and Disease 2017 16:120

    Published on: 17 June 2017

  19. Research

    Efficacy and safety of alirocumab in patients with hypercholesterolemia not adequately controlled with non-statin lipid-lowering therapy or the lowest strength of statin: ODYSSEY NIPPON study design and rationale

    Statins are generally well-tolerated and serious side effects are infrequent, but some patients experience adverse events and reduce their statin dose or discontinue treatment altogether. Alirocumab is a highl...

    Tamio Teramoto, Akira Kondo, Arihiro Kiyosue, Mariko Harada-Shiba, Yasushi Ishigaki, Kimimasa Tobita, Yumiko Kawabata, Asuka Ozaki, Marie T. Baccara-Dinet and Masataka Sata

    Lipids in Health and Disease 2017 16:121

    Published on: 17 June 2017

  20. Research

    The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels

    Previous studies have reported high plasma concentrations of both intestinal apolipoprotein (apo) B-48-containing lipoproteins and PCSK9 in subjects with familial hypercholesterolemia (FH). However, the extent...

    Jean-Philippe Drouin-Chartier, Jean-Charles Hogue, André J. Tremblay, Jean Bergeron, Benoît Lamarche and Patrick Couture

    Lipids in Health and Disease 2017 16:119

    Published on: 15 June 2017

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