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  1. Research

    Caryocar brasiliense oil improves cardiac function by increasing Serca2a/PLB ratio despite no significant changes in cardiovascular risk factors in rats

    Caryocar brasiliense (pequi) oil is high in monounsaturated fat acids (MUFA), especially oleic, and in carotenoids, which have been associated with protection against cardiovascular di...

    Lidiane Guedes Oliveira, Lauane Gomes Moreno, Dirceu Sousa Melo, Liliane Vanessa Costa-Pereira, Mayara Medeiros de Freitas Carvalho, Paulo Henrique Evangelista Silva, Ana Maria Alves, Flávio de Castro Magalhães, Marco Fabrício Dias-Peixoto and Elizabethe Adriana Esteves

    Lipids in Health and Disease 2017 16:37

    Published on: 8 February 2017

  2. Review

    The potential role of mitochondrial ATP synthase inhibitory factor 1 (IF1) in coronary heart disease: a literature review

    Cardiovascular disease (CVD) is the leading cause of death worldwide, and so the search for innovative and accurate biomarkers for guiding prevention, diagnosis, and treatment is a valuable clinical and econom...

    Serban Maierean, Maria-Corina Serban, Manfredi Rizzo, Giuseppe Lippi, Amirhossein Sahebkar and Maciej Banach

    Lipids in Health and Disease 2017 16:35

    Published on: 7 February 2017

  3. Research

    Docosahexaenoic acid increases accumulation of adipocyte triacylglycerol through up-regulation of lipogenic gene expression in pigs

    Changing dietary fatty acid composition in modern diet influences the prevalence of obesity. Increasing evidences suggest favorable effects of n-3 PUFA for protecting against obesity and the metabolic syndrome...

    Chao-Wei Huang, Yu-Jen Chen, Jui-Ting Yang, Ching-Yi Chen, Kolapo M. Ajuwon, Shuen-Ei Chen, Nan-Wei Su, Yu-Shan Chen, Harry J. Mersmann and Shih-Torng Ding

    Lipids in Health and Disease 2017 16:33

    Published on: 7 February 2017

  4. Research

    Opuntia ficus-indica cladodes as a functional ingredient: bioactive compounds profile and their effect on antioxidant quality of bread

    In the context of a balanced diet, the antioxidant-rich food consumption is a preventive way of many degenerative diseases. Consequently, improving the nutraceutical quality of traditional foods such as bakery...

    Lotfi Msaddak, Ola Abdelhedi, Amani Kridene, Mostafa Rateb, Lassaâd Belbahri, Emna Ammar, Moncef Nasri and Nacim Zouari

    Lipids in Health and Disease 2017 16:32

    Published on: 7 February 2017

  5. Research

    The effects of short-term high-fat feeding on exercise capacity: multi-tissue transcriptome changes by RNA sequencing analysis

    The effects of short-term high fat diets on physiology are elusive and the molecular changes following fat overconsumption remain largely unknown. In this study, we aimed to evaluate exercise capacity in mice ...

    Ya Xiao, Wanshan Wang, Liguo Chen, Jieyu Chen, Pingping Jiang, Xiuqiong Fu, Xiaoli Nie, Hiuyee Kwan, Yanyan Liu and Xiaoshan Zhao

    Lipids in Health and Disease 2017 16:28

    Published on: 2 February 2017

  6. Research

    Oxidative stability and lipid oxidation flavoring volatiles in antioxidants treated chicken meat patties during storage

    Chicken meat contains higher percentage of polyunsaturated fatty acids that are susceptible to oxidative deterioration ultimately leading towards lower consumer acceptability for chicken meat products. Accordi...

    Muhammad Sohaib, Faqir Muhammad Anjum, Muhammad Sajid Arshad, Muhammad Imran, Ali Imran and Shahzad Hussain

    Lipids in Health and Disease 2017 16:27

    Published on: 1 February 2017

  7. Research

    Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress

    Progranulin (PGRN) has recently emerged as an important regulator for insulin resistance. However, the direct effect of progranulin in adipose insulin resistance associated with the autophagy mechanism is not ...

    Qinyue Guo, Lin Xu, Huixia Li, Hongzhi Sun, Jiali Liu, Shufang Wu and Bo Zhou

    Lipids in Health and Disease 2017 16:25

    Published on: 31 January 2017

  8. Research

    Common variants in the genes of triglyceride and HDL-C metabolism lack association with coronary artery disease in the Pakistani subjects

    Serum Triglyceride (TG) and High Density Lipoprotein (HDL-C) levels are modifiable coronary artery disease (CAD) risk factors. Polymorphisms in the genes regulating TG and HDL-C levels contribute to the develo...

    Saleem Ullah Shahid, N.A. Shabana, Jackie A. Cooper, Abdul Rehman and Steve E. Humphries

    Lipids in Health and Disease 2017 16:24

    Published on: 31 January 2017

  9. Research

    Non-high-density lipoprotein cholesterol predicts nonfatal recurrent myocardial infarction in patients with ST segment elevation myocardial infarction

    Lipids, which are associated with atherogenesis, clotting, and the fibrinolytic pathway, may be important prognostic indicators of recurrent myocardial infarction. The aim of this study was to determine the pr...

    Ming Gao, Yang Zheng, Weihua Zhang, Yi Cheng, Lin Wang and Ling Qin

    Lipids in Health and Disease 2017 16:20

    Published on: 23 January 2017

  10. Research

    Efficacy, safety, Low density lipoprotein cholesterol lowering, and calculated 10-year cardiovascular risk reduction of alirocumab and evolocumab in addition to maximal tolerated cholesterol lowering therapy: a post-commercialization study

    Efficacy and safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab (ALI) and evolocumab (EVO) have previously been evaluated through controlled clinical trials with selective p...

    Parth Shah, Charles J. Glueck, Naila Goldenberg, Sarah Min, Chris Mahida, Ilana Schlam, Matan Rothschild, Ali Huda and Ping Wang

    Lipids in Health and Disease 2017 16:19

    Published on: 23 January 2017

  11. Research

    The role of fatty acids on ICSI outcomes: a prospective cohort study

    Our objective was to determine the effect of fatty acids (FAs) in serum and follicular fluid (FF) on fertilization and intracytoplasmic sperm injection (ICSI) outcomes.

    Parvaneh Mirabi, Mohammad Javad Chaichi, Sedighe Esmaeilzadeh, Seyed Gholam Ali Jorsaraei, Ali Bijani, Mahjoobeh Ehsani and Seyedeh Fezzeh hashemi Karooee

    Lipids in Health and Disease 2017 16:18

    Published on: 21 January 2017

  12. Research

    The time course of erythrocyte membrane fatty acid concentrations during and after treatment of non-human primates with increasing doses of an omega-3 rich phospholipid preparation derived from krill-oil

    A commonly used measure to reflect the intake of the long-chain omega-3 fatty acids EPA and DHA is the omega-3 index, defined as the sum of EPA + DHA as % of total fatty acids in erythrocyte membrane. When the...

    Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo and Yong-Fu Xiao

    Lipids in Health and Disease 2017 16:16

    Published on: 21 January 2017

  13. Research

    Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties

    PPARγ is an isoform of peroxisome proliferator-activated receptor (PPAR) belonging to a super family of nuclear receptors. PPARγ receptor is found to play a crucial role in the modulation of lipid and glucose ...

    Shalini Muralikumar, Umashankar Vetrivel, Angayarkanni Narayanasamy and Undurti N. Das

    Lipids in Health and Disease 2017 16:17

    Published on: 21 January 2017

  14. Research

    The triglyceride and glucose index (TyG) is an effective biomarker to identify nonalcoholic fatty liver disease

    The triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. We aimed to investigate the ability of TyG, through comparing with the predictive value of alanine aminotransferase...

    Shujun Zhang, Tingting Du, Jianhua Zhang, Huiming Lu, Xuan Lin, Junhui Xie, Yan Yang and Xuefeng Yu

    Lipids in Health and Disease 2017 16:15

    Published on: 19 January 2017

  15. Research

    Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion

    The transient global cerebral hypoperfusion/reperfusion achieved by induction of Bilateral Common Carotid Artery Occlusion followed by Reperfusion (BCCAO/R) may trigger a physiological response in an attempt t...

    Marina Quartu, Laura Poddighe, Tiziana Melis, Maria Pina Serra, Marianna Boi, Sara Lisai, Gianfranca Carta, Elisabetta Murru, Laura Muredda, Maria Collu and Sebastiano Banni

    Lipids in Health and Disease 2017 16:14

    Published on: 19 January 2017

  16. Research

    Dietary intake of n-3 PUFAs modifies the absorption, distribution and bioavailability of fatty acids in the mouse gastrointestinal tract

    Dietary polyunsaturated fatty acids (PUFAs), especially n-3 PUFAs, are important for human health. The intestinal tract, a location that is heavily colonized by microorganisms, is the main organ for absorbing ...

    Qin Yang, Shunhe Wang, Yunqi Ji, Haiqin Chen, Hao Zhang, Wei Chen, Zhennan Gu and Yong Q. Chen

    Lipids in Health and Disease 2017 16:10

    Published on: 17 January 2017

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