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  1. Research

    DbcAMP regulates adipogenesis in sheep inguinal preadipocytes

    The cyclic adenosine-monophosphate (cAMP) pathway is generally recognized as one of the essential pathways for the adipose conversion of rodent preadipocytes in vitro. However, divergent effects of cAMP on adi...

    Delin Kong, Jingjing Cui and Juncai Fu

    Lipids in Health and Disease 2017 16:93

    Published on: 19 May 2017

  2. Review

    Abundance of active ingredients in sea-buckthorn oil

    Vegetable oils are obtained by mechanical extraction or cold pressing of various parts of plants, most often: seeds, fruits, and drupels. Chemically, these oils are compounds of the ester-linked glycerol and h...

    Aleksandra Zielińska and Izabela Nowak

    Lipids in Health and Disease 2017 16:95

    Published on: 19 May 2017

  3. Research

    Liver phospholipids fatty acids composition in response to different types of diets in rats of both sexes

    Dietary intake influence changes in fatty acids (FA) profiles in liver which plays a central role in fatty acid metabolism, triacylglycerol synthesis and energy homeostasis. We investigated the effects of 4-we...

    Slavica Ranković, Tamara Popović, Jasmina Debeljak Martačić, Snježana Petrović, Mirko Tomić, Đurđica Ignjatović, Gordana Tovilović-Kovačević and Maria Glibetić

    Lipids in Health and Disease 2017 16:94

    Published on: 19 May 2017

  4. Research

    Radiotherapy improves serum fatty acids and lipid profile in breast cancer

    Breast cancer is a disease with diverse clinical symptoms, molecular profiles, and its nature to response its therapeutic treatments. Radiotherapy (RT), along with surgery and chemotherapy is a part of treatme...

    Sana Shaikh, Naseem Aslam Channa, Farha Naz Talpur, Muhammad Younis and Naila Tabassum

    Lipids in Health and Disease 2017 16:92

    Published on: 18 May 2017

  5. Research

    Oxidative profiles of LDL and HDL isolated from women with preeclampsia

    Oxidative stress causes biochemical changes in lipids and proteins; these changes can induce damage to the vascular endothelium and create maternal complications that are characteristic of preeclampsia. In thi...

    G. León-Reyes, R. F. Maida-Claros, A. X. Urrutia-Medina, E. Jorge-Galarza, A. M. Guzmán-Grenfell, S. Fuentes-García, R. Medina-Navarro, M. A. Moreno-Eutimio, J. L. Muñoz-Sánchez, J. J. Hicks and Y. D. Torres-Ramos

    Lipids in Health and Disease 2017 16:90

    Published on: 16 May 2017

  6. Research

    Low apolipoprotein M serum levels correlate with Systemic lupus erythematosus disease activity and apolipoprotein M gene polymorphisms with Lupus

    Sequence variation in gene promoters is often associated with disease risk. In this study, we tested the hypothesis that common promoter variation in the APOM gene is associated with systemic lupus erythematosus ...

    Wenhan Du, Ting Shen, Hui Li, Yinyin Liu, Lagu He, Li Tan, Min Hu and Yaping Ren

    Lipids in Health and Disease 2017 16:88

    Published on: 5 May 2017

  7. Review

    The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathway

    Docosahexaenoic acid(DHA) inhibits tumor growth and progression in various cancers, including lung cancer. However, the mechanisms involved remain unclear. The aim of this study was to identify the mechanism o...

    Yuanqin Yin, Chengguang Sui, Fandong Meng, Ping Ma and Youhong Jiang

    Lipids in Health and Disease 2017 16:87

    Published on: 3 May 2017

  8. Review

    Mangiferin: a natural miracle bioactive compound against lifestyle related disorders

    The current review article is an attempt to explain the therapeutic potential of mangiferin, a bioactive compound of the mango, against lifestyle-related disorders. Mangiferin (2-β-D-glucopyranosyl-1,3,6,7-tet...

    Muhammad Imran, Muhammad Sajid Arshad, Masood Sadiq Butt, Joong-Ho Kwon, Muhammad Umair Arshad and Muhammad Tauseef Sultan

    Lipids in Health and Disease 2017 16:84

    Published on: 2 May 2017

  9. Review

    Perilipins: a diversity of intracellular lipid droplet proteins

    Intracellular lipid droplets (LDs) are found in a wide variety of cell types and have been recognized as organelles with unique spherical structures. Although LDs are not stable lipid-depots, they are active s...

    Hiroyuki Itabe, Tomohiro Yamaguchi, Satomi Nimura and Naoko Sasabe

    Lipids in Health and Disease 2017 16:83

    Published on: 28 April 2017

  10. Research

    Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway

    Nonalcoholic fatty liver disease is one of the most common liver diseases in the world and is a typical hepatic manifestation of metabolic syndrome which is characterized with lipid accumulation in liver. Nico...

    Ling-Fang Wang, Xiao-Nv Wang, Cong-Cong Huang, Long Hu, Yun-Fei Xiao, Xiao-Hui Guan, Yi-Song Qian, Ke-Yu Deng and Hong-Bo Xin

    Lipids in Health and Disease 2017 16:82

    Published on: 27 April 2017

  11. Research

    Enhanced status of inflammation and endothelial activation in subjects with familial hypercholesterolaemia and their related unaffected family members: a case control study

    Familial hypercholesterolaemia (FH) leads to premature coronary artery diseases (CAD) which pathophysiologically can be measured by inflammation, endothelial activation and oxidative stress status. However, th...

    Thuhairah Rahman, Nur Suhana Hamzan, Atiqah Mokhsin, Radzi Rahmat, Zubin Othman Ibrahim, Rafezah Razali, Malathi Thevarajah and Hapizah Nawawi

    Lipids in Health and Disease 2017 16:81

    Published on: 24 April 2017

  12. Research

    PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease

    Coronary heart disease (CHD) is an important complication of atherosclerosis. Biomarkers, which associate with CHD development, are potential to predict CHD risk. To determine whether genes showing altered exp...

    Yaowapa Maneerat, Kriengchai Prasongsukarn, Surachet Benjathummarak and Wilanee Dechkhajorn

    Lipids in Health and Disease 2017 16:80

    Published on: 19 April 2017

  13. Research

    Prevalence of overweight and obesity among police officers in Riyadh City and risk factors for cardiovascular disease

    Despite the prevalence of overweight and obesity and increases in associated diseases such as diabetes and heart disease in the Saudi population, no studies have addressed the spread of obesity among Saudi pol...

    Abdullah S. Alghamdi, Mohammed A. Yahya, Ghedeir M. Alshammari and Magdi A. Osman

    Lipids in Health and Disease 2017 16:79

    Published on: 14 April 2017

  14. Research

    Milk protein-based formulas containing different oils affect fatty acids balance in term infants: A randomized blinded crossover clinical trial

    Palm olein is used in infant formula fat blends in order to match the fatty acid profile of human milk. While the effects on fatty acid balance have been evaluated, the use of palm olein in combination with pa...

    Carolina Oliveira de Souza, Maria Efigênia Q. Leite, John Lasekan, Geraldine Baggs, Lorena Silva Pinho, Janice Izabel Druzian, Tereza Cristina M. Ribeiro, Ângela P. Mattos, José A. Menezes-Filho and Hugo Costa-Ribeiro

    Lipids in Health and Disease 2017 16:78

    Published on: 14 April 2017

  15. Research

    A comparison of effects of DPP-4 inhibitor and SGLT2 inhibitor on lipid profile in patients with type 2 diabetes

    Previous studies suggest that dipeptidyl peptidase-4 (DPP-4) inhibitors and sodium glucose cotransporter 2 (SGLT2) inhibitors have different effects on the lipid profile in patients with type 2 diabetes. We in...

    Seon-Ah Cha, Yong-Moon Park, Jae-Seung Yun, Tae-Seok Lim, Ki-Ho Song, Ki-Dong Yoo, Yu-Bae Ahn and Seung-Hyun Ko

    Lipids in Health and Disease 2017 16:58

    Published on: 13 April 2017

  16. Research

    Lipids bearing extruded-spheronized pellets for extended release of poorly soluble antiemetic agent—Meclizine HCl

    Antiemetic agent Meclizine HCl, widely prescribed in vertigo, is available only in immediate release dosage forms. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential...

    Faaiza Qazi, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Muhammad Iqbal Nasiri, Kamran Ahmed and Mansoor Ahmad

    Lipids in Health and Disease 2017 16:75

    Published on: 12 April 2017

  17. Research

    Association of classical markers and establishment of the dyslipidemic sub-phenotype of sickle cell anemia

    Sickle cell anemia (SCA) patients exhibit sub-phenotypes associated to hemolysis and vaso-occlusion. The disease has a chronic inflammatory nature that has been also associated to alterations in the lipid prof...

    Milena Magalhães Aleluia, Caroline Conceição da Guarda, Rayra Pereira Santiago, Teresa Cristina Cardoso Fonseca, Fábia Idalina Neves, Regiana Quinto de Souza, Larissa Alves Farias, Felipe Araújo Pimenta, Luciana Magalhães Fiuza, Thassila Nogueira Pitanga, Júnia Raquel Dutra Ferreira, Elisângela Vitória Adorno, Bruno Antônio Veloso Cerqueira and Marilda de Souza Gonçalves

    Lipids in Health and Disease 2017 16:74

    Published on: 11 April 2017

  18. Research

    Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice

    Eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, C20:4n-6) are long-chain polyunsaturated fatty acids (LCPUFAs) with relevant roles in the organism. EPA and...

    Rodrigo Valenzuela, Francisca Echeverria, Macarena Ortiz, Miguel Ángel Rincón-Cervera, Alejandra Espinosa, María Catalina Hernandez-Rodas, Paola Illesca, Alfonso Valenzuela and Luis A. Videla

    Lipids in Health and Disease 2017 16:64

    Published on: 11 April 2017

  19. Research

    Surface-enhanced Raman spectroscopy of blood serum based on gold nanoparticles for the diagnosis of the oral squamous cell carcinoma

    Oral squamous cell carcinoma (OSCC) is becoming more common across the globe. The prognosis of OSCC is largely dependent on the early detection. But the routine oral cavity examination may delay the diagnosis ...

    Yingyun Tan, Bing Yan, Lili Xue, Yi Li, Xianyang Luo and Ping Ji

    Lipids in Health and Disease 2017 16:73

    Published on: 7 April 2017

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