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  1. Research

    Non-high-density lipoprotein cholesterol predicts nonfatal recurrent myocardial infarction in patients with ST segment elevation myocardial infarction

    Lipids, which are associated with atherogenesis, clotting, and the fibrinolytic pathway, may be important prognostic indicators of recurrent myocardial infarction. The aim of this study was to determine the pr...

    Ming Gao, Yang Zheng, Weihua Zhang, Yi Cheng, Lin Wang and Ling Qin

    Lipids in Health and Disease 2017 16:20

    Published on: 23 January 2017

  2. Research

    Efficacy, safety, Low density lipoprotein cholesterol lowering, and calculated 10-year cardiovascular risk reduction of alirocumab and evolocumab in addition to maximal tolerated cholesterol lowering therapy: a post-commercialization study

    Efficacy and safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab (ALI) and evolocumab (EVO) have previously been evaluated through controlled clinical trials with selective p...

    Parth Shah, Charles J. Glueck, Naila Goldenberg, Sarah Min, Chris Mahida, Ilana Schlam, Matan Rothschild, Ali Huda and Ping Wang

    Lipids in Health and Disease 2017 16:19

    Published on: 23 January 2017

  3. Research

    The role of fatty acids on ICSI outcomes: a prospective cohort study

    Our objective was to determine the effect of fatty acids (FAs) in serum and follicular fluid (FF) on fertilization and intracytoplasmic sperm injection (ICSI) outcomes.

    Parvaneh Mirabi, Mohammad Javad Chaichi, Sedighe Esmaeilzadeh, Seyed Gholam Ali Jorsaraei, Ali Bijani, Mahjoobeh Ehsani and Seyedeh Fezzeh hashemi Karooee

    Lipids in Health and Disease 2017 16:18

    Published on: 21 January 2017

  4. Research

    The time course of erythrocyte membrane fatty acid concentrations during and after treatment of non-human primates with increasing doses of an omega-3 rich phospholipid preparation derived from krill-oil

    A commonly used measure to reflect the intake of the long-chain omega-3 fatty acids EPA and DHA is the omega-3 index, defined as the sum of EPA + DHA as % of total fatty acids in erythrocyte membrane. When the...

    Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo and Yong-Fu Xiao

    Lipids in Health and Disease 2017 16:16

    Published on: 21 January 2017

  5. Research

    Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties

    PPARγ is an isoform of peroxisome proliferator-activated receptor (PPAR) belonging to a super family of nuclear receptors. PPARγ receptor is found to play a crucial role in the modulation of lipid and glucose ...

    Shalini Muralikumar, Umashankar Vetrivel, Angayarkanni Narayanasamy and Undurti N. Das

    Lipids in Health and Disease 2017 16:17

    Published on: 21 January 2017

  6. Research

    The triglyceride and glucose index (TyG) is an effective biomarker to identify nonalcoholic fatty liver disease

    The triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. We aimed to investigate the ability of TyG, through comparing with the predictive value of alanine aminotransferase...

    Shujun Zhang, Tingting Du, Jianhua Zhang, Huiming Lu, Xuan Lin, Junhui Xie, Yan Yang and Xuefeng Yu

    Lipids in Health and Disease 2017 16:15

    Published on: 19 January 2017

  7. Research

    Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion

    The transient global cerebral hypoperfusion/reperfusion achieved by induction of Bilateral Common Carotid Artery Occlusion followed by Reperfusion (BCCAO/R) may trigger a physiological response in an attempt t...

    Marina Quartu, Laura Poddighe, Tiziana Melis, Maria Pina Serra, Marianna Boi, Sara Lisai, Gianfranca Carta, Elisabetta Murru, Laura Muredda, Maria Collu and Sebastiano Banni

    Lipids in Health and Disease 2017 16:14

    Published on: 19 January 2017

  8. Research

    Dietary intake of n-3 PUFAs modifies the absorption, distribution and bioavailability of fatty acids in the mouse gastrointestinal tract

    Dietary polyunsaturated fatty acids (PUFAs), especially n-3 PUFAs, are important for human health. The intestinal tract, a location that is heavily colonized by microorganisms, is the main organ for absorbing ...

    Qin Yang, Shunhe Wang, Yunqi Ji, Haiqin Chen, Hao Zhang, Wei Chen, Zhennan Gu and Yong Q. Chen

    Lipids in Health and Disease 2017 16:10

    Published on: 17 January 2017

  9. Research

    The effects of detraining and training on adipose tissue lipid droplet in obese mice after chronic high-fat diet

    It is well known that exercise promotes lipolysis by stimulating the lipid droplet (LD) signaling pathway. However, few studies have been conducted to examine the effect of detraining with high fat diet (HFD) ...

    Ju Yong Bae, Jinhee Woo, Hee Tae Roh, Yul Hyo Lee, Kangeun Ko, Sunghwun Kang and Ki Ok Shin

    Lipids in Health and Disease 2017 16:13

    Published on: 17 January 2017

  10. Review

    Mouse models of atherosclerosis: a historical perspective and recent advances

    Atherosclerosis represents a significant cause of morbidity and mortality in both the developed and developing countries. Animal models of atherosclerosis have served as valuable tools for providing insights o...

    Yee Ting Lee, Hiu Yu Lin, Yin Wah Fiona Chan, Ka Hou Christien Li, Olivia Tsz Ling To, Bryan P Yan, Tong Liu, Guangping Li, Wing Tak Wong, Wendy Keung and Gary Tse

    Lipids in Health and Disease 2017 16:12

    Published on: 17 January 2017

  11. Research

    Effects of a purified krill oil phospholipid rich in long-chain omega-3 fatty acids on cardiovascular disease risk factors in non-human primates with naturally occurring diabetes type-2 and dyslipidemia

    High serum levels of cholesterol, in particular low-density lipoprotein cholesterol, are considered a significant risk factor for development of cardiovascular disease. Therefore, rigorous treatment regimens w...

    Petter-Arnt Hals, Xiaoli Wang and Yong-Fu Xiao

    Lipids in Health and Disease 2017 16:11

    Published on: 17 January 2017

  12. Research

    Quercetin improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice fed a high-fat diet

    Quercetin, one of the most widely distributed flavonoids in plants, has been demonstrated to reduce hyperlipidaemia and atherosclerotic lesion formation. Reverse cholesterol transport (RCT) plays a crucial rol...

    Yingjie Cui, Pengbo Hou, Fahui Li, Qinghua Liu, Shucun Qin, Guanghai Zhou, Xuelian Xu, Yanhong Si and Shoudong Guo

    Lipids in Health and Disease 2017 16:9

    Published on: 14 January 2017

  13. Research

    Biochemical mechanism underlying hypertriglyceridemia and hepatic steatosis/hepatomegaly induced by acute schisandrin B treatment in mice

    It has been demonstrated that acute oral administration of schisandrin B (Sch B), an active dibenzocyclooctadiene isolated from Schisandrae Fructus (a commonly used traditional Chinese herb), increased serum a...

    Yi Zhang, Jing Zhao, Shu-Feng Zhou, Zhi-Ling Yu, Xiao-Yan Wang, Pei-Li Zhu, Zhu-Sheng Chu, Si-Yuan Pan, Ming Xie and Kam-Ming Ko

    Lipids in Health and Disease 2017 16:8

    Published on: 13 January 2017

  14. Research

    Elevated levels of preβ1-high-density lipoprotein are associated with cholesterol ester transfer protein, the presence and severity of coronary artery disease

    Preβ1-high-density lipoprotein (preβ1-HDL), plays an important role in reverse cholesterol transport and exhibits potent risk for coronary artery disease (CAD). However, the association of plasma preβ1-HDL and...

    Xiao-min Bu, Dong-mei Niu, Jia Wu, Yun-long Yuan, Jia-xi Song and Jun-jun Wang

    Lipids in Health and Disease 2017 16:4

    Published on: 10 January 2017

  15. Research

    Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

    High density lipoprotein (HDL) has been proved to be a protective factor for coronary heart disease. Notably, HDL in atherosclerotic plaques can be nitrated (NO2-oxHDL) and chlorinated (Cl-oxHDL) by myeloperoxida...

    Boda Zhou, Lingyun Zu, Yong Chen, Xilong Zheng, Yuhui Wang, Bing Pan, Min Dong, Enchen Zhou, Mingming Zhao, Youyi Zhang, Lemin Zheng and Wei Gao

    Lipids in Health and Disease 2017 16:3

    Published on: 10 January 2017

  16. Research

    Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups

    Little is known about the association of the single nucleotide polymorphism (SNP) of rs364585 near serine palmitoyl-transferase long-chain base subunit 3 gene (SPTLC3) and serum lipid profiles. The present study ...

    Qing-Hui Zhang, Rui-Xing Yin, Hui Gao, Feng Huang, Jin-Zhen Wu, Shang-Ling Pan, Wei-Xiong Lin and De-Zhai Yang

    Lipids in Health and Disease 2017 16:1

    Published on: 5 January 2017

  17. Research

    Differential effects of palmitoleic acid on human lymphocyte proliferation and function

    Palmitoleic acid (PA) is a n-7 monounsaturated fatty acid (MUFA) secreted by adipose tissue and related to decreased insulin resistance in peripheral tissues. Evidences have been shown that PA also decreased p...

    M. E. P. Passos, H. H. O. Alves, C. M. Momesso, F. G. Faria, G. Murata, M. F. Cury-Boaventura, E. Hatanaka, S. Massao-Hirabara and R. Gorjão

    Lipids in Health and Disease 2016 15:217

    Published on: 13 December 2016

  18. Research

    The effect of marine n-3 polyunsaturated fatty acids on cardiac autonomic and hemodynamic function in patients with psoriatic arthritis: a randomised, double-blind, placebo-controlled trial

    The aim of this study was to investigate the effect of marine n-3 polyunsaturated fatty acids (PUFA) on cardiac autonomic function and vascular function in patients with psoriatic arthritis.

    Salome Kristensen, Erik Berg Schmidt, Annette Schlemmer, Claus Rasmussen, Esther Lindgreen, Martin Berg Johansen and Jeppe Hagstrup Christensen

    Lipids in Health and Disease 2016 15:216

    Published on: 12 December 2016

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