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Table 1 Summary of findings outlining significant differences in food transit time and fecal output for mice exposed to a HF diet with or without phytosterol or ascorbic acid supplement for 72 hours (ACUTE) or a 17-20 week exposure (CHRONIC)

From: Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model

  HF AA PS PSAA
  FOOD TRANSIT TIME FECAL OUTPUT FOOD TRANSIT TIME FECAL OUTPUT FOOD TRANSIT TIME FECAL OUTPUT FOOD TRANSIT TIME FECAL OUTPUT
ACUTE to HF control n/a n/a NSD ↑ NSD ↑ NSD ↑
CHRONIC to HF control Did not test n/a Did not test NSD Did not test NSD Did not test NSD
CHRONIC on HF to HF control n/a n/a NSD NSD ↓ ↓ ↓ ↓
CHRONIC on HF to ACUTE (paired) NSD NSD NSD NSD ↓ ↓ ↓ ↓
  1. Animals in the chronic exposure group were switched to a HF control diet for 72 hours; these animals are referred to as "CHRONIC on HF". Dietary groups with supplements were compared to the HF control within each exposure experiment and assessed for statistically significant differences. To evaluate long-term changes to digestive efficiency, all dietary groups in the "CHRONIC on HF" exposure were compared values obtained from animals acutely exposed to the same dietary groups ("ACUTE"). HF control comparisons to HF control are deemed not applicable (n/a); arrows indicate values are statistically lower or higher than HF control or dietary pair group. NSD = non-significant difference.
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