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Table 1 Summary of findings outlining significant differences in food transit time and fecal output for mice exposed to a HF diet with or without phytosterol or ascorbic acid supplement for 72 hours (ACUTE) or a 17-20 week exposure (CHRONIC)

From: Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model

 

HF

AA

PS

PSAA

 

FOOD TRANSIT TIME

FECAL OUTPUT

FOOD TRANSIT TIME

FECAL OUTPUT

FOOD TRANSIT TIME

FECAL OUTPUT

FOOD TRANSIT TIME

FECAL OUTPUT

ACUTE to HF control

n/a

n/a

NSD

↑

NSD

↑

NSD

↑

CHRONIC to HF control

Did not test

n/a

Did not test

NSD

Did not test

NSD

Did not test

NSD

CHRONIC on HF to HF control

n/a

n/a

NSD

NSD

↓

↓

↓

↓

CHRONIC on HF to ACUTE (paired)

NSD

NSD

NSD

NSD

↓

↓

↓

↓

  1. Animals in the chronic exposure group were switched to a HF control diet for 72 hours; these animals are referred to as "CHRONIC on HF". Dietary groups with supplements were compared to the HF control within each exposure experiment and assessed for statistically significant differences. To evaluate long-term changes to digestive efficiency, all dietary groups in the "CHRONIC on HF" exposure were compared values obtained from animals acutely exposed to the same dietary groups ("ACUTE"). HF control comparisons to HF control are deemed not applicable (n/a); arrows indicate values are statistically lower or higher than HF control or dietary pair group. NSD = non-significant difference.