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  1. Although imbalanced intestinal flora contributes to the pathogenesis of nonalcoholic fatty liver disease (NAFLD), conflicting results have been obtained for patient-derived microbiome composition analyses. A m...

    Authors: Fuxi Li, Junzhao Ye, Congxiang Shao and Bihui Zhong

    Citation: Lipids in Health and Disease 2021 20:22

    Content type: Research

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  2. PCSK9 monoclonal antibody lowers plasma PCSK9 and LDL-cholesterol levels. The manufacturers recommend drug storage at 2–8 °C, and not above 25 °C. This study aimed to investigate drug stability at various temp...

    Authors: Tanawan Kongmalai, Nalinee Chuanchaiyakul, Chattip Sripatumtong, Tunsuda Tansit, Yuttana Srinoulprasert, Nareerak Klinsukon and Nuntakorn Thongtang

    Citation: Lipids in Health and Disease 2021 20:21

    Content type: Research

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  3. High-density lipoprotein cholesterol (HDL-C) hypolipidemia, a major type of dyslipidemia, has been associated with many kinds of diseases, such as stroke, coronary heart disease, obesity and diabetes, and has ...

    Authors: Fang Tang, Jian Wang, Stephen Nicholas, Dongfu Qian and Rugang Liu

    Citation: Lipids in Health and Disease 2021 20:20

    Content type: Research

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  4. Poor cholesterol efflux capacity (CEC) has been proposed to be an independent risk factor for cardiovascular diseases. However, current evidence is inconsistent, especially in rheumatoid arthritis (RA) patient...

    Authors: Binbin Xie, Jiang He, Yong Liu, Ting Liu and Chaoqun Liu

    Citation: Lipids in Health and Disease 2021 20:18

    Content type: Research

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  5. Pemafibrate, a selective PPARα modulator, has the beneficial effects on serum triglycerides (TGs) and very low density lipoprotein (VLDL), especially in patients with diabetes mellitus or metabolic syndrome. H...

    Authors: Ichiro Komiya, Akira Yamamoto, Suguru Sunakawa and Tamio Wakugami

    Citation: Lipids in Health and Disease 2021 20:17

    Content type: Research

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  6. Psoriasis is a common chronic inflammatory skin disease associated with overproduction of interleukin-17A (IL-17A). IL-17A monoclonal antibodies (mAbs) have shown clinical efficacy in psoriasis patients. Altho...

    Authors: Han Cao, Shengmin Su, Qi Yang, Yunchen Le, Lihong Chen, Mengyan Hu, Xiaoyu Guo, Jie Zheng, Xia Li and Yunqiu Yu

    Citation: Lipids in Health and Disease 2021 20:16

    Content type: Research

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  7. The association of circulating lipids with clinical outcomes of drug-resistant castration-resistant prostate cancer (DR-CRPC) is not fully understood. While it is known that increases in select lipids correlat...

    Authors: Lishann M. Ingram, Morgan C. Finnerty, Maryam Mansoura, Chau-Wen Chou and Brian S. Cummings

    Citation: Lipids in Health and Disease 2021 20:15

    Content type: Research

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  8. Familial hypertriglyceridemia (FHTG) is a partially characterized primary dyslipidemia which is frequently confused with other forms hypertriglyceridemia. The aim of this work is to search for specific feature...

    Authors: Ivette Cruz-Bautista, Alicia Huerta-Chagoya, Hortensia Moreno-Macías, Rosario Rodríguez-Guillén, María Luisa Ordóñez-Sánchez, Yayoi Segura-Kato, Roopa Mehta, Paloma Almeda-Valdés, Lizeth Gómez-Munguía, Ximena Ruiz-De Chávez, Ximena Rosas-Flota, Arali Andrade-Amado, Bárbara Bernal-Barroeta, María Guadalupe López-Carrasco, Luz Elizabeth Guillén-Pineda, Angelina López-Estrada…

    Citation: Lipids in Health and Disease 2021 20:14

    Content type: Research

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  9. Dyslipidemia contributes to the pathogenesis of renal dysfunction. Previous research demonstrated that triglycerides (TG), instead of other individual lipid indexes, has a significant link with elevated urinar...

    Authors: Jing Xue, Yuxia Wang, Bing Li, Songyan Yu, Anping Wang, Weiqing Wang, Zhengnan Gao, Xulei Tang, Li Yan, Qin Wan, Guijun Qin, Lulu Chen, Guang Ning and Yiming Mu

    Citation: Lipids in Health and Disease 2021 20:13

    Content type: Research

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  10. Lipoprotein-associated Phospholipase A2 (Lp-PLA2), can exert proinflammatory as well as proatherogenic properties on the vascular wall. The current study sought to evaluate the influence of high Lp-PLA2 levels...

    Authors: Konstantinos Mourouzis, Gerasimos Siasos, Evangelos Oikonomou, Marina Zaromitidou, Vicky Tsigkou, Alexis Antonopoulos, Evanthia Bletsa, Panagiota Stampouloglou, Konstantinos Vlasis, Manolis Vavuranakis and Dimitris Tousoulis

    Citation: Lipids in Health and Disease 2021 20:12

    Content type: Research

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  11. Few studies have developed risk models for dyslipidaemia, especially for rural populations. Furthermore, the performance of genetic factors in predicting dyslipidaemia has not been explored. The purpose of thi...

    Authors: Miaomiao Niu, Liying Zhang, Yikang Wang, Runqi Tu, Xiaotian Liu, Jian Hou, Wenqian Huo, Zhenxing Mao, Zhenfei Wang and Chongjian Wang

    Citation: Lipids in Health and Disease 2021 20:11

    Content type: Research

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  12. Hypertriglyceridemia has arisen as the third leading cause of acute pancreatitis. This study aimed at exploring the association between the severity of hypertriglyceridemia-induced pancreatitis (HTGP) and comp...

    Authors: Lifang Chen, Yingbao Huang, Huajun Yu, Kehua Pan, Zhao Zhang, Yi Man and Dingyuan Hu

    Citation: Lipids in Health and Disease 2021 20:9

    Content type: Research

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  13. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Xiaoli Li, Guilong Li, Tiantian Cheng, Jing Liu, Guangyao Song and Huijuan Ma

    Citation: Lipids in Health and Disease 2021 20:8

    Content type: Correction

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    The original article was published in Lipids in Health and Disease 2020 19:236

  14. Polycystic Ovarian Syndrome (PCOS) is one of the most common endocrinopathies and metabolic disorders in women during their reproductive years. It is often associated with dyslipidemia and other risk factors o...

    Authors: Maryam Yahay, Zahra Heidari, Zahra Allameh and Reza Amani

    Citation: Lipids in Health and Disease 2021 20:7

    Content type: Research

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  15. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is of particular importance in cholesterol metabolism with high levels contributing to hypercholesterolemia. Cholesterol and sphingolipids are low in patie...

    Authors: Susanne Feder, Reiner Wiest, Thomas S. Weiss, Charalampos Aslanidis, Doris Schacherer, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler

    Citation: Lipids in Health and Disease 2021 20:6

    Content type: Research

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  16. Several large clinical trials have confirmed the cardioprotective role of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 2 diabetes. However, whether empagliflozin, as an SGLT2i, coul...

    Authors: Yihai Liu, Jiamin Xu, Mingyue Wu, Biao Xu and Lina Kang

    Citation: Lipids in Health and Disease 2021 20:5

    Content type: Research

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  17. Familial hypercholesterolemia(FH) is one of the most frequent and important monogenic cholesterol pathologies. Traditional and non-traditional cardiovascular risk factors increase the prevalence of atheroscler...

    Authors: Cristiana-Elena Vlad, Liliana Foia, Laura Florea, Irina-Iuliana Costache, Andreea Covic, Roxana Popescu, Delia Reurean-Pintilei and Adrian Covic

    Citation: Lipids in Health and Disease 2021 20:4

    Content type: Research

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  18. Dyslipidemia is considered an independent health risk factor of cardiovascular disease (CVD), a leading cause of mortality in older adults. Despite its importance, there have been few reports on the associatio...

    Authors: Seung Hee Kim and Ki Young Son

    Citation: Lipids in Health and Disease 2021 20:3

    Content type: Research

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  19. Clinical trials have demonstrated that either initiating or up-titrating a statin dose substantially reduce Low-Density Lipoprotein-Cholesterol (LDL-C) levels. However, statin adherence in actual practice tend...

    Authors: Hao Sen Andrew Fang, Qiao Gao, Mong Li Lee, Wynne Hsu and Ngiap Chuan Tan

    Citation: Lipids in Health and Disease 2021 20:2

    Content type: Research

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  20. Elevated triglyceride (TG) levels are a biomarker for cardiovascular disease (CVD) risk. The correlation between serum uric acid (SUA) and TG concentrations in adults or obese children is well established. How...

    Authors: Yuntian Chu, Qianqian Zhao, Mei Zhang, Bo Ban and Hongbing Tao

    Citation: Lipids in Health and Disease 2021 20:1

    Content type: Research

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  21. Nonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have focused on reducing the intake of trans ...

    Authors: Noriko Suzuki-Kemuriyama, Akari Abe, Kiniko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima and Dai Nakae

    Citation: Lipids in Health and Disease 2020 19:251

    Content type: Research

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  22. Emerging data support a role for lipids in non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC) in humans. With experimental models such data can be challenged or validated. Mice fed a low-m...

    Authors: Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler

    Citation: Lipids in Health and Disease 2020 19:250

    Content type: Research

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  23. Lipoproteins at aberrant levels are known to play a role in cardiovascular disease. The metabolite of the insecticide dichlorodiphenyltrichloroethane (DDT), p,p’-dichlorodiphenyldichloroethylene (p,p’-DDE), ph...

    Authors: Juliann Jugan, P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Kärrman, Lars Lind and Michele A. La Merrill

    Citation: Lipids in Health and Disease 2020 19:249

    Content type: Research

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  24. A study conducted on elderly Korean men showed that a high serum triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio was associated with a high risk of developing sarcopenia. We aimed to dete...

    Authors: Na Wang, Mengjun Chen and Danhong Fang

    Citation: Lipids in Health and Disease 2020 19:248

    Content type: Research

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  25. Standard lipid panel assays employing chemical/enzymatic methods measure total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C), from which are calculated estimates of low...

    Authors: Erwin Garcia, Dennis W. Bennett, Margery A. Connelly, Elias J. Jeyarajah, Franklin C. Warf, Irina Shalaurova, Steven P. Matyus, Justyna Wolak-Dinsmore, David N. Oskardmay, Randolph M. Young, Maureen Sampson, Alan T. Remaley and James D. Otvos

    Citation: Lipids in Health and Disease 2020 19:247

    Content type: Research

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  26. This article has been retracted. Please see the Retraction Notice for more detail: https://​doi.​org/​10.​1186/​s12944-020-01416-2

    Authors: Yan-Guo Qin, Lan-Yu Zhu, Chen-Yu Wang, Bo-Yan Zhang, Qing-Yu Wang, Rui-Yan Li and Zhen Liu

    Citation: Lipids in Health and Disease 2020 19:246

    Content type: Retraction Note

    Published on:

    The original article was published in Lipids in Health and Disease 2015 14:70

  27. The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio has been considered an alternative marker for hepatic steatosis. However, few studies have investigated the association of the ALT/AST ...

    Authors: Yang Zou, Ling Zhong, Chong Hu and Guotai Sheng

    Citation: Lipids in Health and Disease 2020 19:245

    Content type: Research

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  28. Since sarcopenia is an important risk factor for falls or cardiovascular disease, early detection and prevention of sarcopenia are being increasingly emphasized. Emerging evidence has indicated relationships b...

    Authors: Sung-Ho Ahn, Jun-Hyuk Lee and Ji-Won Lee

    Citation: Lipids in Health and Disease 2020 19:243

    Content type: Research

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  29. The non-HDL-cholesterol to HDL-cholesterol (NHDLC/HDLC) ratio is closely related to a variety of dyslipidemia-related diseases. This study examined the relationship between the NHDLC/HDLC ratio and non-alcohol...

    Authors: Shouxing Yang, Jinwei Zhong, Mengsi Ye, Lei Miao, Guangrong Lu, Changlong Xu, Zhanxiong Xue and Xinhe Zhou

    Citation: Lipids in Health and Disease 2020 19:242

    Content type: Research

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  30. The association of the atherogenic index of plasma (AIP), an emerging lipid index that can predict the risk for cardiovascular disease, with adverse outcomes in type 2 diabetes mellitus (T2DM) patients with ac...

    Authors: Xiaoteng Ma, Yan Sun, Yujing Cheng, Hua Shen, Fei Gao, Jing Qi, Lixia Yang, Zhijian Wang, Dongmei Shi, Yuyang Liu, Xiaoli Liu and Yujie Zhou

    Citation: Lipids in Health and Disease 2020 19:240

    Content type: Research

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  31. Reduction in elevated serum cholesterol concentrations is important in the management of individuals at risk of atherosclerotic cardiovascular disease (ASCVD), such as myocardial infarction and thrombotic stro...

    Authors: Adrian M. Di Bisceglie, Gerald F. Watts, Philip Lavin, Meng Yu, Ru Bai and Liping Liu

    Citation: Lipids in Health and Disease 2020 19:239

    Content type: Research

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  32. The low-density lipoprotein cholesterol/high-density lipoprotein- cholesterol (LDL-C/HDL-C) ratio is an excellent predictor of cardiovascular disease (CVD). However, previous studies linking the LDL-C/HDL-C ra...

    Authors: Yu Yu, Minghui Li, Xiao Huang, Wei Zhou, Tao Wang, Lingjuan Zhu, Congcong Ding, Yu Tao, Huihui Bao and Xiaoshu Cheng

    Citation: Lipids in Health and Disease 2020 19:238

    Content type: Research

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  33. Attaining acceptable levels of LDL Cholesterol (LDL-C) significantly improves cardiovascular (CV) outcomes in patients with type 2 diabetes mellitus (T2DM). The LDL-C target attainment and the characteristics ...

    Authors: Fahri Bayram, Alper Sonmez, Cem Haymana, Tevfik Sabuncu, Oguzhan Sitki Dizdar, Eren Gurkan, Ayse Kargili Carlioglu, Kemal Agbaht, Didem Ozdemir, Ibrahim Demirci, Cem Barcin, Serpil Salman, Tamer Tetiker, Mustafa Kemal Balci, Nur Kebapci, Canan Ersoy…

    Citation: Lipids in Health and Disease 2020 19:237

    Content type: Research

    Published on:

  34. Recent studies have suggested the triglyceride-glucose index (TyG index) may serve as a suitable substitute for insulin resistance. However, evidence for the relationship between TyG index and risk of diabetes...

    Authors: Xiaoli Li, Guilong Li, Tiantian Cheng, Jing Liu, Guangyao Song and Huijuan Ma

    Citation: Lipids in Health and Disease 2020 19:236

    Content type: Research

    Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2021 20:8

  35. Insulin resistance has a vital role in the pathophysiology of polycystic ovary syndrome (PCOS). Previous investigations have shown that some lipid ratios could be a simple clinical indicator of insulin resista...

    Authors: Asma Kheirollahi, Maryam Teimouri, Mehrdad Karimi, Akram Vatannejad, Nariman Moradi, Nasrin Borumandnia and Asie Sadeghi

    Citation: Lipids in Health and Disease 2020 19:235

    Content type: Research

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  36. Previous studies have shown that serum carcinoembryonic antigen (CEA) is independently associated with metabolic syndrome (MetS). However, these studies were mainly cross-sectional analyses, and cause was not ...

    Authors: Yafei Liu, Zhaohui Du, Jiadong Ji, Jingru Li, Deming Bi and Fang Tang

    Citation: Lipids in Health and Disease 2020 19:233

    Content type: Research

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  37. In the recent years, chronic obstructive pulmonary disease (COPD) has been found to be associated with a higher risk of new-onset osteoporotic fracture (NOF). However, the existence of such an association in t...

    Authors: Hung-Yi Chen, Pei-Yu Su, Tsung-Kun Lin and Gwo-Ping Jong

    Citation: Lipids in Health and Disease 2020 19:232

    Content type: Research

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  38. Data on the relationship between nontraditional lipid profiles [total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio, triglyceride (TG)/HDL-C ratio, low-density lipoprotein cholesterol (LD...

    Authors: Congcong Ding, Yang Chen, Yumeng Shi, Minghui Li, Lihua Hu, Wei Zhou, Tao Wang, Lingjuan Zhu, Xiao Huang, Huihui Bao and Xiaoshu Cheng

    Citation: Lipids in Health and Disease 2020 19:231

    Content type: Research

    Published on:

  39. Meteorin-like (Metrnl) is an adipokine with insulin sensitizing and anti-inflammatory properties that has been discovered recently. The relation among Metrnl, Inflammatory Bowel Disease (IBD), and obesity has ...

    Authors: Afsane Gholamrezayi, Maryam Mohamadinarab, Pegah Rahbarinejad, Soudabeh Fallah, Shekufe Rezghi Barez, Leila Setayesh, Nariman Moradi, Reza Fadaei, Elham Chamani and Tahmine Tavakoli

    Citation: Lipids in Health and Disease 2020 19:230

    Content type: Research

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  40. Both triglyceride glucose-body mass index (TyG-BMI) and non-alcoholic fatty liver disease (NAFLD) are linked to insulin resistance (IR). Prospective studies linking TyG-BMI to NAFLD have been limited by short ...

    Authors: Yaling Li, Rui Zheng, Jie Li, Shuyi Feng, Li Wang and Zhiming Huang

    Citation: Lipids in Health and Disease 2020 19:229

    Content type: Research

    Published on:

  41. Despite the fact that the majority of gallstones formed in the gallbladder are mainly composed of cholesterol, as they are formed from cholesterol-supersaturated bile, and hypercholesterolemia is a common meta...

    Authors: Binwu Sheng, Qingbin Zhao, Mao Ma and Jianqin Zhang

    Citation: Lipids in Health and Disease 2020 19:228

    Content type: Research

    Published on:

  42. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Anahita Izadi, Leila Khedmat, Reza Tavakolizadeh and Sayed Yousef Mojtahedi

    Citation: Lipids in Health and Disease 2020 19:227

    Content type: Correction

    Published on:

    The original article was published in Lipids in Health and Disease 2020 19:65

  43. Prediabetes has become a pandemic. This study aimed to identify a better predictor for the incidence of prediabetes, which we hypothesize to be the triglyceride-glucose (TyG) index, a simplified insulin resist...

    Authors: Jing Wen, Anping Wang, Guangxu Liu, Meiping Wang, Yingting Zuo, Wei Li, Qi Zhai, Yiming Mu, Herbert Y. Gaisano, Yan He and Jingtao Dou

    Citation: Lipids in Health and Disease 2020 19:226

    Content type: Research

    Published on:

  44. The receptors for advanced glycation end products (RAGE) are increased in atherosclerotic plaques. Soluble (s)RAGE decreases, whereas the extracellular newly identified receptor for advanced glycation end prod...

    Authors: Eva O. Melin, Jonatan Dereke and Magnus Hillman

    Citation: Lipids in Health and Disease 2020 19:223

    Content type: Research

    Published on:

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