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  1. Content type: Research

    The interaction between folate pathway gene polymorphisms and homocysteine, serum lipid leverls are poorly understood in patients with recurrent spontaneous abortion (RSA). The aim of this study is to explore ...

    Authors: Zhong Lin, Qianxi Li, Yifan Sun, Jingchun Huang, Wan Wang, Jinjian Fu, Jianhua Xu and Dingyuan Zeng

    Citation: Lipids in Health and Disease 2019 18:143

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  2. Content type: Research

    Insulin resistance (IR) and fat accumulation in visceral adipose tissue are key players in developing type 2 diabetes (T2D). Several adipose tissue derived-gene polymorphisms are related to higher body mass in...

    Authors: Amirhosein Khoshi, Mehdi Kaffash Bajestani, Habibesadat Shakeri, Golnaz Goodarzi and Fatemeh Azizi

    Citation: Lipids in Health and Disease 2019 18:142

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  3. Content type: Research

    The adipocyte expansion is a critical process with implications in the pathogenesis of obesity associated metabolic syndrome. Impaired adipogenesis leads to dysfunctional, hypertrophic adipocytes, local inflam...

    Authors: Ioana Hristov, Veronica Mocanu, Florin Zugun-Eloae, Luminita Labusca, Iustina Cretu-Silivestru, Teodor Oboroceanu, Crina Tiron, Adrian Tiron, Alexandrina Burlacu, Alin Constantin Pinzariu, Ioana Armasu, Radu Mircea Neagoe, Adrian Covic, Viorel Scripcariu and Daniel Vasile Timofte

    Citation: Lipids in Health and Disease 2019 18:141

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  4. Content type: Research

    The aim of this study was to assess the prognostic value of red blood cell distribution width (RDW) in patients with coronary artery disease undergoing percutaneous coronary intervention (PCI).

    Authors: Ting-Ting Wu, Ying-Ying Zheng, Xian-Geng Hou, Yi Yang, Xiang Ma, Yi-Tong Ma and Xiang Xie

    Citation: Lipids in Health and Disease 2019 18:140

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  5. Content type: Review

    Breast fat necrosis (FN) originates from aseptic fat saponification, which is a typical lipid cyst or a spiculated lesion called mammographic presentation which mimics malignancy. In order to avoid biopsy, it ...

    Authors: Narges Vasei, Azita Shishegar, Forouzan Ghalkhani and Mohammad Darvishi

    Citation: Lipids in Health and Disease 2019 18:139

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  6. Content type: Research

    Hepatitis B virus (HBV) infection remains a global health issue associated with substantial morbidity and mortality. Serum apolipoprotein C3 (ApoC3) and apolipoprotein A5 (ApoA5) levels were decreased in chron...

    Authors: Yu Cui, Xiang-Dan Cui, Meng Xu, Min Fang and Mei-Juan Cai

    Citation: Lipids in Health and Disease 2019 18:138

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  7. Content type: Review

    Breast cancer is a heterogeneous disease with increasing incidence and mortality and represents one of the most common cancer types worldwide. Low-density lipoprotein (LDL) is a complex particle composed of se...

    Authors: Xuefeng Guan, Zhuo Liu, Zhen Zhao, Xuefeng Zhang, Siteng Tao, Bao Yuan, Jiabao Zhang, Dawei Wang, Qing Liu and Yu Ding

    Citation: Lipids in Health and Disease 2019 18:137

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  8. Content type: Research

    Bone marrow-derived endothelial progenitor cells (EPCs) are shown to attenuate lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in animal models. However, the molecular mechanism is largely unknown.

    Authors: Yan Jin, Chen Yang, Xintong Sui, Quan Cai, Liang Guo and Zhi Liu

    Citation: Lipids in Health and Disease 2019 18:136

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  9. Content type: Short report

    Heat induced by infrared (IR) radiation from sun exposure increases skin temperature and can lead to thermal and photo-aging. However, little is known about the relationship between heat induced by IR radiatio...

    Authors: Hyuk Chul Kwon, Tae Yang Kim, Chun Mong Lee, Kwang Sik Lee and Kun Kook Lee

    Citation: Lipids in Health and Disease 2019 18:135

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  10. Content type: Research

    Lecithin-cholesterol acyltransferase (LCAT) is a plasma enzyme that esterifies cholesterol in high- and low-density lipoproteins (HDL and LDL). Mutations in LCAT gene causes familial LCAT deficiency, which is ...

    Authors: Hugo E. Tobar, Luis R. Cataldo, Trinidad González, Ricardo Rodríguez, Valentina Serrano, Antonio Arteaga, Ana Álvarez-Mercado, Carlos F. Lagos, Lucas Vicuña, José P. Miranda, Ana Pereira, Carolina Bravo, Concepción M. Aguilera, Susana Eyheramendy, Ricardo Uauy, Álvaro Martínez…

    Citation: Lipids in Health and Disease 2019 18:132

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  11. Content type: Research

    Familial hypercholesterolemia (FH) is an important cause of premature coronary artery disease (CAD). Prognosis data are lacking in patients with FH and coronary artery disease particularly in the era of widesp...

    Authors: Xu Wang, Gaojun Cai, Yingying Wang, Ran Liu, Ziwei Xi, Gexuan Li, Wenhui Wen, Yue Wu, Chenggang Wang, Qingwei Ji, Xinguo Wang, Qian Zhang, Yujie Zeng, Luya Wang, Wei Liu and Yujie Zhou

    Citation: Lipids in Health and Disease 2019 18:131

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  12. Content type: Research

    Lipid ratios, for example total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C), are associated with type 2 diabetes mellitus (T2DM)...

    Authors: Wen Guo, Pei Qin, Jing Lu, Xiaona Li, Wenfang Zhu, Nianzhen Xu, Jianming Wang and Qun Zhang

    Citation: Lipids in Health and Disease 2019 18:130

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  13. Content type: Research

    Apolipoprotein E (ApoE) plays an important role in lipid metabolism and clearance. Statins are the most common drugs used to modulate the lipid profile in the clinic therapy; the associations between ApoE poly...

    Authors: Lei Zhang, Siying He, Zuhua Li, Xuedong Gan, Siwei Li, Xiaohuan Cheng, Na Yang and Fang Zheng

    Citation: Lipids in Health and Disease 2019 18:129

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  14. Content type: Research

    Polygonum Multiflorum Thunb(PMT) has multiple biological effects, such as anti-inflammatory, lipid-lowering, anti-aging and so on. Therefore, D-galactose-induced aging mice were used to study the effect of PMT on...

    Authors: Jiangquan Yang, Yuqi He, Jiayi Zou, Lin Xu, Fang Fan and Zhenglong Ge

    Citation: Lipids in Health and Disease 2019 18:128

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  15. Content type: Research

    Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a recently emerged measure of inflammation and oxidative stress and has been used to predict multiple cardiovascular abnormalities, but data rela...

    Authors: Hao-Yu Wang, Wen-Rui Shi, Xin Yi, Ya-Ping Zhou, Zhi-Qin Wang and Ying-Xian Sun

    Citation: Lipids in Health and Disease 2019 18:127

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  16. Content type: Research

    Doxorubicin (DOX) is an anthracycline agent mostly prescribed for various cancers. However, its treatment is contiguous with toxic effects. Acacia hydaspica prevented drug-induced hepatic-toxicity in animals with...

    Authors: Tayyaba Afsar, Suhail Razak and Ali Almajwal

    Citation: Lipids in Health and Disease 2019 18:126

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  17. Content type: Research

    Exercise has proved effective in attenuating the unfavourable response normally associated with postprandial hypertriglyceridemia (PHTG) and accompanying oxidative stress. Yet, the acute effects of prior exerc...

    Authors: Malcolm Brown, Conor M. McClean, Gareth W. Davison, John C. W. Brown and Marie H. Murphy

    Citation: Lipids in Health and Disease 2019 18:125

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  18. Content type: Research

    Lipid profiles are believed to play an important role in the tumorigenesis and progression of prostate cancer (PCa), but research combining those data is lacking. Therefore, this meta-analysis aims to assess t...

    Authors: Xiaonan Zheng, Xin Han, Hang Xu, Jianzhong Ai, Lu Yang and Qiang Wei

    Citation: Lipids in Health and Disease 2019 18:124

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  19. Content type: Research

    Since oleic acid (OA, 18:1 c9) and arachidonic acid (AA, 20:4 n6) may have antagonistic actions, it is of interest to assess their relative abundances. We previously reported an inverse correlation between % O...

    Authors: Arne Torbjørn Høstmark and Anna Haug

    Citation: Lipids in Health and Disease 2019 18:123

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  20. Content type: Research

    Melanocortin 3 receptor (MC3R), a rhodopsin-like G protein-coupled receptor, is an important regulator of metabolism. Although MC3R knock-out (KO) mice and rats were generated in earlier studies, the function ...

    Authors: Yajun Yin, Haiyang Hao, Xingbin Xu, Liangcai Shen, Wenjing Wu, Jin Zhang and Qiuyan Li

    Citation: Lipids in Health and Disease 2019 18:122

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  21. Content type: Research

    Combination of statins and clopidogrel is frequently administered in patients with coronary artery disease (CAD). They are mainly activated and eliminated in the liver by cytochrome P450 isoenzyme 3A4 (CYP3A4)...

    Authors: Ke An, Rong Huang, Sai Tian, Dan Guo, Jiaqi Wang, Hongyan Lin and Shaohua Wang

    Citation: Lipids in Health and Disease 2019 18:121

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  22. Content type: Research

    Elevated low-density lipoprotein cholesterol (LDL-C) levels in childhood have recently been found to be the strongest predictive risk factor for coronary artery disease in adulthood. There is an increased leve...

    Authors: Qianqian Zhao, Yingzhe Jiang, Mei Zhang, Yuntian Chu, Baolan Ji, Hui Pan and Bo Ban

    Citation: Lipids in Health and Disease 2019 18:120

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  23. Content type: Research

    The study sought to assess the impact of statin therapy on survival in patients presenting with ventricular tachyarrhythmias.

    Authors: Jonas Rusnak, Michael Behnes, Tobias Schupp, Siegfried Lang, Linda Reiser, Gabriel Taton, Armin Bollow, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Uzair Ansari, Ibrahim El-Battrawy, Thomas Bertsch, Christoph A. Nienaber, Muharrem Akin, Kambis Mashayekhi…

    Citation: Lipids in Health and Disease 2019 18:119

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  24. Content type: Research

    Fatty acid synthase (FASN) is overexpressed in most human carcinomas, including non-small cell lung cancer (NSCLC), and contributes to poor prognosis. An increasing number of studies have highlighted the poten...

    Authors: Ligong Chang, Surong Fang, Yubao Chen, Zhenhua Yang, Yuan Yuan, Jing Zhang, Liang Ye and Wei Gu

    Citation: Lipids in Health and Disease 2019 18:118

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  25. Content type: Research

    Oxidized low-density lipoprotein (ox-LDL) is crucial in cardiac injury. Apolipoprotein-J (ApoJ) contributes to antiapoptotic effects in the heart. We aimed to evaluate the protective effects of ApoJ against ox...

    Authors: Yanzhuo Ma, Zhi Gong, Kai Nan, Shuying Qi, Yu Chen, Chao Ding, Dongmei Wang and Leisheng Ru

    Citation: Lipids in Health and Disease 2019 18:117

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  26. Content type: Research

    Angiopoietin-like protein 3(ANGPTL3) is well acknowledged as a key regulator of lipid metabolism. Now, there have not been enough data to explain the mechanism of hyperlipidemia related proteinuria. In this st...

    Authors: Xia Gao, Yanhong Suo, Min Zhang, Yan Wang, Xin Gao, Qiu Bing and Qingju Liu

    Citation: Lipids in Health and Disease 2019 18:116

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  27. Content type: Research

    Experimental and epidemiological studies show that bergamot polyphenolic fraction (BPF) ameliorates the serum lipemic profile, normalizes blood pressure and improves non alcoholic fatty liver disease in patien...

    Authors: Vincenzo Musolino, Micaela Gliozzi, Saverio Nucera, Cristina Carresi, Jessica Maiuolo, Rocco Mollace, Sara Paone, Francesca Bosco, Federica Scarano, Miriam Scicchitano, Stefano Ruga, Maria Caterina Zito, Carmen Colica, Roberta Macrì, Ernesto Palma, Salvatore Ragusa…

    Citation: Lipids in Health and Disease 2019 18:115

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  28. Content type: Review

    Vision disorders are one of the most serious complications of diabetes mellitus (DM) affecting the quality of life of patients and eventually cause blindness. The ocular lesions in diabetes mellitus are locate...

    Authors: Aldo R. Eynard and Gaston Repossi

    Citation: Lipids in Health and Disease 2019 18:114

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  29. Content type: Research

    Smoking is a major risk factor for dyslipidemia. However, it remains to be clarified whether light smoking in Asian women affects lipid profiles and lipid-related indices. The aim of this study was to determin...

    Authors: Yuri Chimura, Takashi Daimon and Ichiro Wakabayashi

    Citation: Lipids in Health and Disease 2019 18:113

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  30. Content type: Research

    Hyperuricemia as a metabolic disease is usually associated with lipid metabolic disorder. The purpose of this study is to identify potential lipid biomarkers and provide the evidence for the relationship betwe...

    Authors: Fei Yang, Mingyu Liu, Nankun Qin, Shuangshuang Li, Mengqi Yu, Chengxiang Wang and Qun Ma

    Citation: Lipids in Health and Disease 2019 18:112

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  31. Content type: Research

    Hepatic lipase (HL, encoded by LIPC) is a glycoprotein primarily synthesized and secreted by hepatocytes. Previous studies had demonstrated that HL is crucial for reverse cholesterol transport and affects the met...

    Authors: Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su and Yu-Lin Ko

    Citation: Lipids in Health and Disease 2019 18:111

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  32. Content type: Research

    Genome-wide association study (GWAS) identified chromosome 12p13 rs12425791 and rs11833579 as susceptibility loci of ischemic stroke (IS) in a European population. However, conflicting results were obtained in...

    Authors: Zhi-Neng Zeng, Ling-Ling Liu, Yong-Ling He, Xiang Shi and Ye-Sheng Wei

    Citation: Lipids in Health and Disease 2019 18:110

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  33. Content type: Research

    Atrial lipid metabolic remodeling is critical for the process of atrial fibrillation (AF). Abnormal Fatty acid (FA) metabolism in cardiomyocytes is involved in the pathogenesis of AF. MET (Metformin), an AMPK ...

    Authors: Fan Bai, Yaozhong Liu, Tao Tu, Biao Li, Yichao Xiao, Yingxu Ma, Fen Qin, Jing Xie, Shenghua Zhou and Qiming Liu

    Citation: Lipids in Health and Disease 2019 18:109

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  34. Content type: Research

    This study aims to investigate the effect of lipid metabolism disorder on liver function in patients with malignant tumors after chemotherapy.

    Authors: Yan Sun, Nie Zhang, Yun-Long Ding, Li-Jiang Yu, Jun Cai, De Ma, Wu Yang, Wang-Kun Lu and Jia-Li Niu

    Citation: Lipids in Health and Disease 2019 18:108

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  35. Content type: Research

    Atherosclerotic cardiovascular disease (ASCVD) refers to a series of diseases caused by atherosclerosis (AS). It is one of the most important causes of death worldwide. According to the inflammatory response t...

    Authors: He-ming Huang, Xin Jiang, Meng-lei Hao, Meng-jie Shan, Yong Qiu, Gai-feng Hu, Quan Wang, Zi-qing Yu, Ling-bing Meng and Yun-yun Zou

    Citation: Lipids in Health and Disease 2019 18:107

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  36. Content type: Research

    Lipid metabolism imbalance has been recognized as one of the major drivers of impaired glucose metabolism in the context of type 2 diabetes mellitus (T2DM), the rates of which are steadily increasing worldwide...

    Authors: Ji-fang Wang, Hai-ming Zhang, Yan-yan Li, Song Xia, Yin Wei, Ling Yang, Dong Wang, Jing-jing Ye, Hao-xiang Li, Jing Yuan and Rui-rong Pan

    Citation: Lipids in Health and Disease 2019 18:106

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  37. Content type: Review

    Studies had investigated the associations between proprotein convertase subtilisin/kexin type 9 SNP rs562556 and serum lipids levels and response to statin treatment, however, the results remained inconclusive...

    Authors: Junlan Chuan, Zhengxu Qian, Yuan Zhang, Rongsheng Tong and Min Peng

    Citation: Lipids in Health and Disease 2019 18:105

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  38. Content type: Research

    In recent years, an increasing number of studies have proved that circulating miRNAs could be used for the early diagnosis of cardiovascular diseases and even play vital roles in the evaluation of therapeutic ...

    Authors: Jiang Xu, Zixuan Chen, Yingge Wang, Xiaohong Wang, Lu Chen, Tingting Yuan, Xiangming Tang, Yaoyao Lu, Hongmei Chen, Miaolei Chen, Zuowei Duan, Jianglin Fan, Jingyan Liang and Xinjiang Zhang

    Citation: Lipids in Health and Disease 2019 18:104

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  39. Content type: Research

    Patients with diabetes mellitus were often accompanied with hyperlipidemia. ATP-binding cassette sub-family A member1 (ABCA1) promotes the efflux of lipids and thereby mediates the metabolism of cholesterol. T...

    Authors: Huili Yan, Lei Cheng, Ruoshuang Jia, Huiqian Yao, Hongxia Wu, Yaqian Shen, Ying Zhang, Panpan Hao and Zhongwen Zhang

    Citation: Lipids in Health and Disease 2019 18:103

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  40. Content type: Research

    We previously reported that the consumption of 8 g of protein per day in the form of lactic-fermented egg white (LAFEW) improves visceral fat obesity. In this study, we investigated the minimum effective intak...

    Authors: Ryosuke Matsuoka, Keiko Kamachi, Mika Usuda, Yasunobu Masuda, Masaaki Kunou, Akira Tanaka and Kazunori Utsunomiya

    Citation: Lipids in Health and Disease 2019 18:102

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  41. Content type: Review

    Growing evidence suggests that ethanolamine plasmalogens (PlsEtns), a subtype of phospholipids, have a close association with Alzheimer’s disease (AD). Decreased levels of PlsEtns have been commonly found in A...

    Authors: Xiao Q. Su, Junming Wang and Andrew J. Sinclair

    Citation: Lipids in Health and Disease 2019 18:100

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  42. Content type: Research

    The value of atherogenic index of plasma (AIP) as a predictive biomarker for coronary artery disease (CAD) remains controversial. In addition, whether AIP is associated with the risk of acute coronary syndrome...

    Authors: Gaojun Cai, Wei Liu, Sai Lv, Xu Wang, Yonghe Guo, Zhenxian Yan, Yu Du and Yujie Zhou

    Citation: Lipids in Health and Disease 2019 18:99

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  43. Content type: Research

    Essential hypertension can cause many kinds of cardiovascular diseases. The pathogenesis of essential hypertension is very complex, and the mechanism is still unclear. The microRNAs have been identified as nov...

    Authors: Yuanzheng Ye, Jianzhong Yang, Wenkui Lv, Yanmei Lu, Ling Zhang, Ying Zhang, Zulifeiya Musha, Ping Fan, Bin Yang, Xianhui Zhou and Baopeng Tang

    Citation: Lipids in Health and Disease 2019 18:98

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  44. Content type: Research

    Evidence shows that low serum vitamin D concentrations account for an increased risk of obesity by inducing vitamin D receptor (VDR) hypofunction. Although the correlation between single nucleotide polymorphisms ...

    Authors: Fang Shen, Yan Wang, Hualei Sun, Dongdong Zhang, Fei Yu, Songcheng Yu, Han Han, Jun Wang, Yue Ba, Chongjian Wang, Wenjie Li and Xing Li

    Citation: Lipids in Health and Disease 2019 18:97

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  45. Content type: Research

    The majority of pregnant women present an increase in lipids. To investigate the influence of the non-fasting state in the lipid and lipoprotein profile in pregnancy, we have aimed to assess the dynamic change...

    Authors: Yulong Li, Jianxun He, Xiaoli Zeng, Song Zhao, Xuebing Wang and Hui Yuan

    Citation: Lipids in Health and Disease 2019 18:96

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  46. Content type: Research

    The incidence of premature myocardial infarction (PMI) has gradually increased in recent years. Genetics plays a central role in the development of PMI. Familial hypercholesterolemia (FH) is one of the most co...

    Authors: Chongyou Lee, Yuxia Cui, Junxian Song, Sufang Li, Feng Zhang, Manyan Wu, Long Li, Dan Hu and Hong Chen

    Citation: Lipids in Health and Disease 2019 18:95

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  47. Content type: Research

    Obesity, widely recognized as a serious health concern, is characterized by profoundly altered metabolism. However, the intermediate metabolites involved in this change remain largely unknown.

    Authors: Minoo Bagheri, Abolghasem Djazayery, Farshad Farzadfar, Lu Qi, Mir Saeed Yekaninejad, Stella Aslibekyan, Maryam Chamari, Hossein Hassani, Berthold Koletzko and Olaf Uhl

    Citation: Lipids in Health and Disease 2019 18:94

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