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  1. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is of particular importance in cholesterol metabolism with high levels contributing to hypercholesterolemia. Cholesterol and sphingolipids are low in patie...

    Authors: Susanne Feder, Reiner Wiest, Thomas S. Weiss, Charalampos Aslanidis, Doris Schacherer, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler

    Citation: Lipids in Health and Disease 2021 20:6

    Content type: Research

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  2. Several large clinical trials have confirmed the cardioprotective role of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 2 diabetes. However, whether empagliflozin, as an SGLT2i, coul...

    Authors: Yihai Liu, Jiamin Xu, Mingyue Wu, Biao Xu and Lina Kang

    Citation: Lipids in Health and Disease 2021 20:5

    Content type: Research

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  3. Familial hypercholesterolemia(FH) is one of the most frequent and important monogenic cholesterol pathologies. Traditional and non-traditional cardiovascular risk factors increase the prevalence of atheroscler...

    Authors: Cristiana-Elena Vlad, Liliana Foia, Laura Florea, Irina-Iuliana Costache, Andreea Covic, Roxana Popescu, Delia Reurean-Pintilei and Adrian Covic

    Citation: Lipids in Health and Disease 2021 20:4

    Content type: Research

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  4. Dyslipidemia is considered an independent health risk factor of cardiovascular disease (CVD), a leading cause of mortality in older adults. Despite its importance, there have been few reports on the associatio...

    Authors: Seung Hee Kim and Ki Young Son

    Citation: Lipids in Health and Disease 2021 20:3

    Content type: Research

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  5. Clinical trials have demonstrated that either initiating or up-titrating a statin dose substantially reduce Low-Density Lipoprotein-Cholesterol (LDL-C) levels. However, statin adherence in actual practice tend...

    Authors: Hao Sen Andrew Fang, Qiao Gao, Mong Li Lee, Wynne Hsu and Ngiap Chuan Tan

    Citation: Lipids in Health and Disease 2021 20:2

    Content type: Research

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  6. Elevated triglyceride (TG) levels are a biomarker for cardiovascular disease (CVD) risk. The correlation between serum uric acid (SUA) and TG concentrations in adults or obese children is well established. How...

    Authors: Yuntian Chu, Qianqian Zhao, Mei Zhang, Bo Ban and Hongbing Tao

    Citation: Lipids in Health and Disease 2021 20:1

    Content type: Research

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  7. Nonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have focused on reducing the intake of trans ...

    Authors: Noriko Suzuki-Kemuriyama, Akari Abe, Kiniko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima and Dai Nakae

    Citation: Lipids in Health and Disease 2020 19:251

    Content type: Research

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  8. Emerging data support a role for lipids in non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC) in humans. With experimental models such data can be challenged or validated. Mice fed a low-m...

    Authors: Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler

    Citation: Lipids in Health and Disease 2020 19:250

    Content type: Research

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  9. Lipoproteins at aberrant levels are known to play a role in cardiovascular disease. The metabolite of the insecticide dichlorodiphenyltrichloroethane (DDT), p,p’-dichlorodiphenyldichloroethylene (p,p’-DDE), ph...

    Authors: Juliann Jugan, P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Kärrman, Lars Lind and Michele A. La Merrill

    Citation: Lipids in Health and Disease 2020 19:249

    Content type: Research

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  10. A study conducted on elderly Korean men showed that a high serum triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio was associated with a high risk of developing sarcopenia. We aimed to dete...

    Authors: Na Wang, Mengjun Chen and Danhong Fang

    Citation: Lipids in Health and Disease 2020 19:248

    Content type: Research

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  11. Standard lipid panel assays employing chemical/enzymatic methods measure total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C), from which are calculated estimates of low...

    Authors: Erwin Garcia, Dennis W. Bennett, Margery A. Connelly, Elias J. Jeyarajah, Franklin C. Warf, Irina Shalaurova, Steven P. Matyus, Justyna Wolak-Dinsmore, David N. Oskardmay, Randolph M. Young, Maureen Sampson, Alan T. Remaley and James D. Otvos

    Citation: Lipids in Health and Disease 2020 19:247

    Content type: Research

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  12. This article has been retracted. Please see the Retraction Notice for more detail: https://​doi.​org/​10.​1186/​s12944-020-01416-2

    Authors: Yan-Guo Qin, Lan-Yu Zhu, Chen-Yu Wang, Bo-Yan Zhang, Qing-Yu Wang, Rui-Yan Li and Zhen Liu

    Citation: Lipids in Health and Disease 2020 19:246

    Content type: Retraction Note

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    The original article was published in Lipids in Health and Disease 2015 14:70

  13. The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio has been considered an alternative marker for hepatic steatosis. However, few studies have investigated the association of the ALT/AST ...

    Authors: Yang Zou, Ling Zhong, Chong Hu and Guotai Sheng

    Citation: Lipids in Health and Disease 2020 19:245

    Content type: Research

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  14. Since sarcopenia is an important risk factor for falls or cardiovascular disease, early detection and prevention of sarcopenia are being increasingly emphasized. Emerging evidence has indicated relationships b...

    Authors: Sung-Ho Ahn, Jun-Hyuk Lee and Ji-Won Lee

    Citation: Lipids in Health and Disease 2020 19:243

    Content type: Research

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  15. The non-HDL-cholesterol to HDL-cholesterol (NHDLC/HDLC) ratio is closely related to a variety of dyslipidemia-related diseases. This study examined the relationship between the NHDLC/HDLC ratio and non-alcohol...

    Authors: Shouxing Yang, Jinwei Zhong, Mengsi Ye, Lei Miao, Guangrong Lu, Changlong Xu, Zhanxiong Xue and Xinhe Zhou

    Citation: Lipids in Health and Disease 2020 19:242

    Content type: Research

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  16. The association of the atherogenic index of plasma (AIP), an emerging lipid index that can predict the risk for cardiovascular disease, with adverse outcomes in type 2 diabetes mellitus (T2DM) patients with ac...

    Authors: Xiaoteng Ma, Yan Sun, Yujing Cheng, Hua Shen, Fei Gao, Jing Qi, Lixia Yang, Zhijian Wang, Dongmei Shi, Yuyang Liu, Xiaoli Liu and Yujie Zhou

    Citation: Lipids in Health and Disease 2020 19:240

    Content type: Research

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  17. Reduction in elevated serum cholesterol concentrations is important in the management of individuals at risk of atherosclerotic cardiovascular disease (ASCVD), such as myocardial infarction and thrombotic stro...

    Authors: Adrian M. Di Bisceglie, Gerald F. Watts, Philip Lavin, Meng Yu, Ru Bai and Liping Liu

    Citation: Lipids in Health and Disease 2020 19:239

    Content type: Research

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  18. The low-density lipoprotein cholesterol/high-density lipoprotein- cholesterol (LDL-C/HDL-C) ratio is an excellent predictor of cardiovascular disease (CVD). However, previous studies linking the LDL-C/HDL-C ra...

    Authors: Yu Yu, Minghui Li, Xiao Huang, Wei Zhou, Tao Wang, Lingjuan Zhu, Congcong Ding, Yu Tao, Huihui Bao and Xiaoshu Cheng

    Citation: Lipids in Health and Disease 2020 19:238

    Content type: Research

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  19. Attaining acceptable levels of LDL Cholesterol (LDL-C) significantly improves cardiovascular (CV) outcomes in patients with type 2 diabetes mellitus (T2DM). The LDL-C target attainment and the characteristics ...

    Authors: Fahri Bayram, Alper Sonmez, Cem Haymana, Tevfik Sabuncu, Oguzhan Sitki Dizdar, Eren Gurkan, Ayse Kargili Carlioglu, Kemal Agbaht, Didem Ozdemir, Ibrahim Demirci, Cem Barcin, Serpil Salman, Tamer Tetiker, Mustafa Kemal Balci, Nur Kebapci, Canan Ersoy…

    Citation: Lipids in Health and Disease 2020 19:237

    Content type: Research

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  20. Recent studies have suggested the triglyceride-glucose index (TyG index) may serve as a suitable substitute for insulin resistance. However, evidence for the relationship between TyG index and risk of diabetes...

    Authors: Xiaoli Li, Guilong Li, Tiantian Cheng, Jing Liu, Guangyao Song and Huijuan Ma

    Citation: Lipids in Health and Disease 2020 19:236

    Content type: Research

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  21. Insulin resistance has a vital role in the pathophysiology of polycystic ovary syndrome (PCOS). Previous investigations have shown that some lipid ratios could be a simple clinical indicator of insulin resista...

    Authors: Asma Kheirollahi, Maryam Teimouri, Mehrdad Karimi, Akram Vatannejad, Nariman Moradi, Nasrin Borumandnia and Asie Sadeghi

    Citation: Lipids in Health and Disease 2020 19:235

    Content type: Research

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  22. Previous studies have shown that serum carcinoembryonic antigen (CEA) is independently associated with metabolic syndrome (MetS). However, these studies were mainly cross-sectional analyses, and cause was not ...

    Authors: Yafei Liu, Zhaohui Du, Jiadong Ji, Jingru Li, Deming Bi and Fang Tang

    Citation: Lipids in Health and Disease 2020 19:233

    Content type: Research

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  23. In the recent years, chronic obstructive pulmonary disease (COPD) has been found to be associated with a higher risk of new-onset osteoporotic fracture (NOF). However, the existence of such an association in t...

    Authors: Hung-Yi Chen, Pei-Yu Su, Tsung-Kun Lin and Gwo-Ping Jong

    Citation: Lipids in Health and Disease 2020 19:232

    Content type: Research

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  24. Data on the relationship between nontraditional lipid profiles [total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio, triglyceride (TG)/HDL-C ratio, low-density lipoprotein cholesterol (LD...

    Authors: Congcong Ding, Yang Chen, Yumeng Shi, Minghui Li, Lihua Hu, Wei Zhou, Tao Wang, Lingjuan Zhu, Xiao Huang, Huihui Bao and Xiaoshu Cheng

    Citation: Lipids in Health and Disease 2020 19:231

    Content type: Research

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  25. Meteorin-like (Metrnl) is an adipokine with insulin sensitizing and anti-inflammatory properties that has been discovered recently. The relation among Metrnl, Inflammatory Bowel Disease (IBD), and obesity has ...

    Authors: Afsane Gholamrezayi, Maryam Mohamadinarab, Pegah Rahbarinejad, Soudabeh Fallah, Shekufe Rezghi Barez, Leila Setayesh, Nariman Moradi, Reza Fadaei, Elham Chamani and Tahmine Tavakoli

    Citation: Lipids in Health and Disease 2020 19:230

    Content type: Research

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  26. Both triglyceride glucose-body mass index (TyG-BMI) and non-alcoholic fatty liver disease (NAFLD) are linked to insulin resistance (IR). Prospective studies linking TyG-BMI to NAFLD have been limited by short ...

    Authors: Yaling Li, Rui Zheng, Jie Li, Shuyi Feng, Li Wang and Zhiming Huang

    Citation: Lipids in Health and Disease 2020 19:229

    Content type: Research

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  27. Despite the fact that the majority of gallstones formed in the gallbladder are mainly composed of cholesterol, as they are formed from cholesterol-supersaturated bile, and hypercholesterolemia is a common meta...

    Authors: Binwu Sheng, Qingbin Zhao, Mao Ma and Jianqin Zhang

    Citation: Lipids in Health and Disease 2020 19:228

    Content type: Research

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  28. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Anahita Izadi, Leila Khedmat, Reza Tavakolizadeh and Sayed Yousef Mojtahedi

    Citation: Lipids in Health and Disease 2020 19:227

    Content type: Correction

    Published on:

    The original article was published in Lipids in Health and Disease 2020 19:65

  29. Prediabetes has become a pandemic. This study aimed to identify a better predictor for the incidence of prediabetes, which we hypothesize to be the triglyceride-glucose (TyG) index, a simplified insulin resist...

    Authors: Jing Wen, Anping Wang, Guangxu Liu, Meiping Wang, Yingting Zuo, Wei Li, Qi Zhai, Yiming Mu, Herbert Y. Gaisano, Yan He and Jingtao Dou

    Citation: Lipids in Health and Disease 2020 19:226

    Content type: Research

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  30. Congenital hyper-homocysteinemia (HHcy) is caused by a defective cystathionine β-synthase (CBS) gene, and is frequently associated with dyslipdemia. The aim of this study was to further elucidate the effect of mu...

    Authors: Ting Zhang, Rui Lu, Yibing Chen, Yuguo Yuan, Shaozheng Song, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Yong Cheng and Jingyan Liang

    Citation: Lipids in Health and Disease 2020 19:224

    Content type: Research

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  31. The receptors for advanced glycation end products (RAGE) are increased in atherosclerotic plaques. Soluble (s)RAGE decreases, whereas the extracellular newly identified receptor for advanced glycation end prod...

    Authors: Eva O. Melin, Jonatan Dereke and Magnus Hillman

    Citation: Lipids in Health and Disease 2020 19:223

    Content type: Research

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  32. Lung cancer has high morbidity and mortality across the globe, and lung adenocarcinoma (LUAD) is the most common histologic subtype. Disordered lipid metabolism is related to the development of cancer. Analysi...

    Authors: Jinyou Li, Qiang Li, Zhenyu Su, Qi Sun, Yong Zhao, Tienan Feng, Jiayuan Jiang, Feng Zhang and Haitao Ma

    Citation: Lipids in Health and Disease 2020 19:222

    Content type: Research

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  33. Stroke is a sudden disorder of cerebral blood circulation. Many studies have illustrated that dyslipidemia, hypertension, diabetes, smoking and excessive drinking are the traditional risk factors for stroke. T...

    Authors: Yan Mao, Lin Yang, Qian Chen, Guoqing Li, Yao Sun, Jiamin Wu, Zichao Xiong, Yuanwei Liu, Haiyue Li, Jianfeng Liu and Yong Zhang

    Citation: Lipids in Health and Disease 2020 19:221

    Content type: Research

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  34. This study aimed to analyze the incidence of early postpartum dyslipidemia and its potential predictors in women with a history of gestational diabetes mellitus (GDM).

    Authors: Ling Pei, Huangmeng Xiao, Fenghua Lai, Zeting Li, Zhuyu Li, Shufan Yue, Haitian Chen, Yanbing Li and Xiaopei Cao

    Citation: Lipids in Health and Disease 2020 19:220

    Content type: Research

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  35. The content of triacylglycerol (TAG) in the liver is known to rapidly increase after a single bout of exercise followed by recovery to sedentary levels. The response of other hepatic lipids, and acyl chain com...

    Authors: Gregory C. Henderson, Valeria Martinez Tenorio and Marc A. Tuazon

    Citation: Lipids in Health and Disease 2020 19:219

    Content type: Research

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  36. The triglyceride-glucose index (TyG) is a reliable predictor of non-alcoholic fatty liver disease (NAFLD). Its association with the severity of hepatic steatosis and liver fibrosis in NAFLD is poorly understoo...

    Authors: Wen Guo, Jing Lu, Pei Qin, Xiaona Li, Wenfang Zhu, Juan Wu, Nianzhen Xu and Qun Zhang

    Citation: Lipids in Health and Disease 2020 19:218

    Content type: Research

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  37. This study explored the relationships between the low−/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) and other clinical indicators and ischaemic stroke (IS) in patients with non-valvular atrial fibr...

    Authors: Xiao-Xue Zhang, Meng Wei, Lu-Xiang Shang, Yan-Mei Lu, Ling Zhang, Yao-Dong Li, Jiang-Hua Zhang, Qiang Xing, Zu Kela Tu-Erhong, Bao-Peng Tang and Xian-Hui Zhou

    Citation: Lipids in Health and Disease 2020 19:217

    Content type: Research

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  38. Intermittent calorie restriction (ICR) is a novel method of dietary restriction for body weight control with the potential to improve obesity-related cardiometabolic markers, but the impact of this diet on sub...

    Authors: Mahsa Maroofi and Javad Nasrollahzadeh

    Citation: Lipids in Health and Disease 2020 19:216

    Content type: Research

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  39. Leptin is an adipokine, adipocyte-derived compound, which acts both as a hormone and cytokine. It is mainly synthesized by adipocytes of white adipose tissue. Leptin possesses pleiotropic functions including, ...

    Authors: Klaudia Dopytalska, Agnieszka Baranowska-Bik, Marek Roszkiewicz, Wojciech Bik and Irena Walecka

    Citation: Lipids in Health and Disease 2020 19:215

    Content type: Review

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  40. The process of autophagy is integral to cellular function. In this process, proteins, organelles, and metabolites are engulfed in a lipid vesicle and trafficked to a lysosome for degradation. Its central role ...

    Authors: Alejandro Soto-Avellaneda and Brad E. Morrison

    Citation: Lipids in Health and Disease 2020 19:214

    Content type: Review

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  41. Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasm...

    Authors: Maryam Sadat Moussavi Javardi, Zahra Madani, Ariyo Movahedi, Majid Karandish and Behnood Abbasi

    Citation: Lipids in Health and Disease 2020 19:213

    Content type: Research

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  42. Negatively charged very-low-density lipoprotein (VLDL-χ) in metabolic syndrome (MetS) patients exerts cytotoxic effects on endothelial cells and atrial myocytes. Atrial cardiomyopathy, manifested by atrial rem...

    Authors: Hsiang-Chun Lee, Shyi-Jang Shin, Jih-Kai Huang, Ming-Yen Lin, Yu-Hsun Lin, Liang-Yin Ke, He-Jiun Jiang, Wei-Chung Tsai, Min-Fang Chao and Yi-Hsiung Lin

    Citation: Lipids in Health and Disease 2020 19:210

    Content type: Research

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  43. This systematic review and meta-analysis aimed to assess the effects of whey protein on serum lipoproteins and glycemic status in patients with metabolic syndrome (MetS) and related disorders.

    Authors: Elaheh Amirani, Alireza Milajerdi, Željko Reiner, Hamed Mirzaei, Mohammad Ali Mansournia and Zatollah Asemi

    Citation: Lipids in Health and Disease 2020 19:209

    Content type: Review

    Published on:

  44. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Agata Bielecka-Dabrowa, Ibadete Bytyçi, Stephan Von Haehling, Stefan Anker, Jacek Jozwiak, Jacek Rysz, Adrian V. Hernandez, Gani Bajraktari, Dimitri P. Mikhailidis and Maciej Banach

    Citation: Lipids in Health and Disease 2020 19:208

    Content type: Correction

    Published on:

    The original article was published in Lipids in Health and Disease 2019 18:188

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