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  1. Research

    Association between Low-density lipoprotein cholesterol and occipital periventricular hyperintensities in a group of Chinese patients: an observational study

    While occipital periventricular hyperintensities (OPVHs) are among the most common mild white matter hyperintensities, the clinical factors associated with OPVHs remain unclear. In this study, we investigated ...

    Dazhi Duan, Lin Shen, Chun Cui, Tongsheng Shu and Jian Zheng

    Lipids in Health and Disease 2017 16:48

    Published on: 27 February 2017

  2. Research

    Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice

    Dietary intervention is the cornerstone of non-alcoholic steatohepatitis (NASH) treatment. However, histological evidence of its efficacy is limited and its impact on hepatic pathways involved in NASH is under...

    Jef Verbeek, Pieter Spincemaille, Ilse Vanhorebeek, Greet Van den Berghe, Ingrid Vander Elst, Petra Windmolders, Jos van Pelt, Schalk van der Merwe, Pierre Bedossa, Frederik Nevens, Bruno Cammue, Karin Thevissen and David Cassiman

    Lipids in Health and Disease 2017 16:46

    Published on: 23 February 2017

  3. Research

    Histomorphology, ultrastructure and fatty acid composition of the adipose tissue in pansteatitis, the potentials in understanding the underlying mechanism and diagnosis of pansteatitis in the Nile crocodile

    In an effort to characterize the fat body and other adipose tissue in the Nile crocodile and the effects of pansteatitis on the structure and composition of the adipose tissue, we evaluated the regional variat...

    O. I. Azeez, J. G. Myburgh, R. A. Meintjes, M. C. Oosthuizen and J. P. Chamunorwa

    Lipids in Health and Disease 2017 16:47

    Published on: 23 February 2017

  4. Research

    Assessment of triglyceride and cholesterol in overweight people based on multiple linear regression and artificial intelligence model

    The prevalence of high hyperlipemia is increasing around the world. Our aims are to analyze the relationship of triglyceride (TG) and cholesterol (TC) with indexes of liver function and kidney function, and to...

    Jing Ma, Jiong Yu, Guangshu Hao, Dan Wang, Yanni Sun, Jianxin Lu, Hongcui Cao and Feiyan Lin

    Lipids in Health and Disease 2017 16:42

    Published on: 20 February 2017

  5. Research

    Controlling of growth performance, lipid deposits and fatty acid composition of chicken meat through a probiotic, Lactobacillus johnsonii during subclinical Clostridium perfringens infection

    Meat is considered as a major source of polyunsaturated fatty acid (PUFA) which is essential for humans, therefore its lipid level and fatty acid composition have drawn great attention. As no clinical sign can...

    Hesong Wang, Xueqin Ni, Lei Liu, Dong Zeng, Jing Lai, Xiaodan Qing, Guangyao Li, Kangcheng Pan and Bo Jing

    Lipids in Health and Disease 2017 16:38

    Published on: 10 February 2017

  6. Research

    Does a lack of physical activity explain the rheumatoid arthritis lipid profile?

    In rheumatoid arthritis (RA), cardiovascular risk is associated with paradoxical reductions in total cholesterol, low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C). ...

    Hiba AbouAssi, Margery A. Connelly, Lori A. Bateman, K. Noelle Tune, Janet L. Huebner, Virginia B. Kraus, Deborah A. Winegar, James D. Otvos, William E. Kraus and Kim M. Huffman

    Lipids in Health and Disease 2017 16:39

    Published on: 10 February 2017

  7. Research

    Caryocar brasiliense oil improves cardiac function by increasing Serca2a/PLB ratio despite no significant changes in cardiovascular risk factors in rats

    Caryocar brasiliense (pequi) oil is high in monounsaturated fat acids (MUFA), especially oleic, and in carotenoids, which have been associated with protection against cardiovascular di...

    Lidiane Guedes Oliveira, Lauane Gomes Moreno, Dirceu Sousa Melo, Liliane Vanessa Costa-Pereira, Mayara Medeiros de Freitas Carvalho, Paulo Henrique Evangelista Silva, Ana Maria Alves, Flávio de Castro Magalhães, Marco Fabrício Dias-Peixoto and Elizabethe Adriana Esteves

    Lipids in Health and Disease 2017 16:37

    Published on: 8 February 2017

  8. Research

    Docosahexaenoic acid increases accumulation of adipocyte triacylglycerol through up-regulation of lipogenic gene expression in pigs

    Changing dietary fatty acid composition in modern diet influences the prevalence of obesity. Increasing evidences suggest favorable effects of n-3 PUFA for protecting against obesity and the metabolic syndrome...

    Chao-Wei Huang, Yu-Jen Chen, Jui-Ting Yang, Ching-Yi Chen, Kolapo M. Ajuwon, Shuen-Ei Chen, Nan-Wei Su, Yu-Shan Chen, Harry J. Mersmann and Shih-Torng Ding

    Lipids in Health and Disease 2017 16:33

    Published on: 7 February 2017

  9. Research

    Opuntia ficus-indica cladodes as a functional ingredient: bioactive compounds profile and their effect on antioxidant quality of bread

    In the context of a balanced diet, the antioxidant-rich food consumption is a preventive way of many degenerative diseases. Consequently, improving the nutraceutical quality of traditional foods such as bakery...

    Lotfi Msaddak, Ola Abdelhedi, Amani Kridene, Mostafa Rateb, Lassaâd Belbahri, Emna Ammar, Moncef Nasri and Nacim Zouari

    Lipids in Health and Disease 2017 16:32

    Published on: 7 February 2017

  10. Review

    The potential role of mitochondrial ATP synthase inhibitory factor 1 (IF1) in coronary heart disease: a literature review

    Cardiovascular disease (CVD) is the leading cause of death worldwide, and so the search for innovative and accurate biomarkers for guiding prevention, diagnosis, and treatment is a valuable clinical and econom...

    Serban Maierean, Maria-Corina Serban, Manfredi Rizzo, Giuseppe Lippi, Amirhossein Sahebkar and Maciej Banach

    Lipids in Health and Disease 2017 16:35

    Published on: 7 February 2017

  11. Research

    The effects of short-term high-fat feeding on exercise capacity: multi-tissue transcriptome changes by RNA sequencing analysis

    The effects of short-term high fat diets on physiology are elusive and the molecular changes following fat overconsumption remain largely unknown. In this study, we aimed to evaluate exercise capacity in mice ...

    Ya Xiao, Wanshan Wang, Liguo Chen, Jieyu Chen, Pingping Jiang, Xiuqiong Fu, Xiaoli Nie, Hiuyee Kwan, Yanyan Liu and Xiaoshan Zhao

    Lipids in Health and Disease 2017 16:28

    Published on: 2 February 2017

  12. Research

    Oxidative stability and lipid oxidation flavoring volatiles in antioxidants treated chicken meat patties during storage

    Chicken meat contains higher percentage of polyunsaturated fatty acids that are susceptible to oxidative deterioration ultimately leading towards lower consumer acceptability for chicken meat products. Accordi...

    Muhammad Sohaib, Faqir Muhammad Anjum, Muhammad Sajid Arshad, Muhammad Imran, Ali Imran and Shahzad Hussain

    Lipids in Health and Disease 2017 16:27

    Published on: 1 February 2017

  13. Research

    Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress

    Progranulin (PGRN) has recently emerged as an important regulator for insulin resistance. However, the direct effect of progranulin in adipose insulin resistance associated with the autophagy mechanism is not ...

    Qinyue Guo, Lin Xu, Huixia Li, Hongzhi Sun, Jiali Liu, Shufang Wu and Bo Zhou

    Lipids in Health and Disease 2017 16:25

    Published on: 31 January 2017

  14. Research

    Common variants in the genes of triglyceride and HDL-C metabolism lack association with coronary artery disease in the Pakistani subjects

    Serum Triglyceride (TG) and High Density Lipoprotein (HDL-C) levels are modifiable coronary artery disease (CAD) risk factors. Polymorphisms in the genes regulating TG and HDL-C levels contribute to the develo...

    Saleem Ullah Shahid, N.A. Shabana, Jackie A. Cooper, Abdul Rehman and Steve E. Humphries

    Lipids in Health and Disease 2017 16:24

    Published on: 31 January 2017

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