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  1. AdipoR1 and AdipoR2 (AdipoRs) are plasma membrane proteins often considered to act as adiponectin receptors with a ceramidase activity. Additionally, the AdipoRs and their yeast and C. elegans orthologs are emerg...

    Authors: Mario Ruiz, Marcus Henricsson, Jan Borén and Marc Pilon

    Citation: Lipids in Health and Disease 2021 20:173

    Content type: Research

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  2. Citation: Lipids in Health and Disease 2021 20:172

    Content type: Correction

    Published on:

    The original article was published in Lipids in Health and Disease 2021 20:155

  3. The effect of comorbid hypertriglyceridemia (HTG) and abdominal obesity (AO) on acute pancreatitis (AP) remains unclear. The aim of this study was to explore the effect of comorbid HTG and AO and discuss which...

    Authors: Xiaoxi Yang, Jiajun He, Shuli Ma, Tingting Wang, Quping Zhu, Fei Cao, Yuanhao Li, Chuting Yang, Chaowu Chen, Guotao Lu, Lianghao Hu, Jun Liu and Weiwei Chen

    Citation: Lipids in Health and Disease 2021 20:171

    Content type: Research

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  4. Dyslipoproteinemias can be classified by their distinct lipoprotein patterns, which helps determine atherosclerotic cardiovascular disease (ASCVD) risk and directs lipid management but this has required advanc...

    Authors: Maureen Sampson, Rami A. Ballout, Daniel Soffer, Anna Wolska, Sierra Wilson, Jeff Meeusen, Leslie J. Donato, Erica Fatica, James D. Otvos, Eliot A. Brinton, Robert S. Rosenson, Peter Wilson, Marcelo Amar, Robert Shamburek, Sotirios K. Karathanasis and Alan T. Remaley

    Citation: Lipids in Health and Disease 2021 20:170

    Content type: Research

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  5. 15-lipoxygenase is one of the key enzymes for the metabolism of unsaturated fatty acids that its manipulation has been proposed recently as a new molecular target for regulating cancer cell growth. Aberrant ex...

    Authors: Mohammad Amin Vaezi, Banafsheh Safizadeh, Amir Reza Eghtedari, Seyedeh Sara Ghorbanhosseini, Mostafa Rastegar, Vahid Salimi and Masoumeh Tavakoli-Yaraki

    Citation: Lipids in Health and Disease 2021 20:169

    Content type: Review

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  6. Serum lipid abnormalities are generally considered as a major risk factor for type 2 diabetes mellitus (T2DM). However, evidence for the effect of long-term serum lipid fluctuations on future T2DM probability ...

    Authors: Qian Sun, Jingchao Liu, Lei Wu, Yue Sun, Jianrong Jin, Sudan Wang, Jing Wu, Yang Jing, Hui Zhou and Chen Dong

    Citation: Lipids in Health and Disease 2021 20:168

    Content type: Research

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  7. Osteonecrosis of the femoral head (ONFH) is a common but intractable disease that appears to involve lipid metabolic disorders. Although numerous studies have demonstrated that high blood levels of low-density...

    Authors: Xin-Yuan Wang, Tian-Le Ma, Kang-Ning Chen, Zhi-Ying Pang, Hao Wang, Jun-Ming Huang, Guo-Bin Qi, Chen-Zhong Wang, Zeng-Xin Jiang, Lin-Jing Gong, Zhe Wang, Chang Jiang and Zuo-Qin Yan

    Citation: Lipids in Health and Disease 2021 20:167

    Content type: Research

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  8. Laparoscopic colorectal surgery causes a lower stress response than open surgery. Adiponectin is mainly derived from adipocytes and has antidiabetic, antioxidative, and anti-inflammatory capabilities. The obje...

    Authors: Wenjiao Shi, Jian Lou, Xiaodan Zhang, Yun Ji, Xiaojian Weng and Jianer Du

    Citation: Lipids in Health and Disease 2021 20:166

    Content type: Research

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  9. Anlotinib, a small molecule for multi-target tyrosine kinase inhibition, is the third or further line of defense for treatment of non-small cell lung cancer (NSCLC). Findings from an ALTER0303 phase III trial ...

    Authors: Mengqiu Tang, Chao Song, Yaowen Zhang, Xiaoyu Xu, Chen Wang, Zhanchun Zhang and Tian Chen

    Citation: Lipids in Health and Disease 2021 20:165

    Content type: Research

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  10. Quercetin (QUE) is a flavonol reported with anti-inflammatory and antioxidant activities, and previous results from the group of this study have demonstrated its neuroprotective effect against lipopolysacchari...

    Authors: Xin-Ran Gao, Zheng Chen, Ke Fang, Jing-Xian Xu and Jin-Fang Ge

    Citation: Lipids in Health and Disease 2021 20:164

    Content type: Research

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  11. The relationship between body mass index (BMI) and low-density lipoprotein cholesterol (LDL-C) has not been clearly elucidated in middle-aged and older adults. This study aimed to evaluate the non-linear dose-...

    Authors: Haibin Li, Jiahui Ma, Deqiang Zheng, Xia Li, Xiuhua Guo, Jing Wang and Pixiong Su

    Citation: Lipids in Health and Disease 2021 20:162

    Content type: Research

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  12. Triglyceride glucose-body mass index (TyG-BMI) has been recommended as an alternative indicator of insulin resistance. However, the association between TyG-BMI and pre-diabetes remains to be elucidated.

    Authors: Chunyuan Jiang, Ruijuan Yang, Maobin Kuang, Meng Yu, Mingchun Zhong and Yang Zou

    Citation: Lipids in Health and Disease 2021 20:161

    Content type: Research

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  13. The high drug resistance and metabolic reprogramming of clear cell renal cell carcinoma (ccRCC) are considered responsible for poor prognosis. In-depth research at multiple levels is urgently warranted to illu...

    Authors: Wen Li, Xiaobin Wang, Xianbin Zhang, Peng Gong, Degang Ding, Ning Wang and Zhifeng Wang

    Citation: Lipids in Health and Disease 2021 20:160

    Content type: Research

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  14. Non-high-density lipoprotein cholesterol (non-HDL-C) may be an independent risk factor for cardio-cerebrovascular disease (CVD); however, the cutoff level in patients on maintenance hemodialysis (MHD) is unknown.

    Authors: Denggui Luo, Yueming Luo, Yanhong Zou, Yuanzhao Xu, Bo Fu, Dong Yang, Jun Yang, Cai Xu, Shuyi Ling, Shunmin Li and Airong Qi

    Citation: Lipids in Health and Disease 2021 20:159

    Content type: Research

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  15. Increased evidence has reported the association of genetic polymorphisms of Apolipoprotein E (APOE) with serum lipids. However, few studies have explored the combined effects of APOE, gender, and age.

    Authors: Xiaofeng Liu, Qingwen Lin, Kengna Fan, Minjie Tang, Weiqing Zhang, Bin Yang and Qishui Ou

    Citation: Lipids in Health and Disease 2021 20:158

    Content type: Research

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  16. To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia.

    Authors: Andrey Sivkov, Natalya Chernus, Roman Gorenkov, Sergey Sivkov, Svetlana Sivkova and Tamara Savina

    Citation: Lipids in Health and Disease 2021 20:157

    Content type: Research

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  17. Rash, photosensitivity, erythema multiforme, and the acute generalized exanthematous pustulosis (AGEP) are relatively uncommon adverse reactions of drugs. To date, the etiology is not well understood and indiv...

    Authors: Markus Blaess, Lars Kaiser, Oliver Sommerfeld, René Csuk and Hans-Peter Deigner

    Citation: Lipids in Health and Disease 2021 20:156

    Content type: Hypothesis

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  18. Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and restricted and repetitive behaviors. Neuroinflammation and abnormal lipid mediators have b...

    Authors: Afaf El-Ansary, Manan Alhakbany, Abeer Aldbass, Hanan Qasem, Sarah Al-Mazidi, Ramesa Shafi Bhat and Laila Al-Ayadhi

    Citation: Lipids in Health and Disease 2021 20:155

    Content type: Research

    Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2021 20:172

  19. We investigated the role of ANGPTL3 and ANGPTL4 in atherosclerosis development and determined whether plasma concentrations of ANGPTL3 and ANGPTL4 are related to the degree of coronary stenosis.

    Authors: Ting Sun, Wanlin Zhan, Lijiang Wei, Zuojun Xu, Li Fan, Yang Zhuo, Changqian Wang and Junfeng Zhang

    Citation: Lipids in Health and Disease 2021 20:154

    Content type: Research

    Published on:

  20. Despite recent advances in recognizing more reliable indicators to estimate the coronary artery disease (CAD) patients’ response to treatment and prognosis, less attention has been paid to evaluating them in c...

    Authors: Marjan Mahdavi-Roshan, Arsalan Salari, Azin Vakilpour, Amir Savar Rakhsh and Zeinab Ghorbani

    Citation: Lipids in Health and Disease 2021 20:153

    Content type: Research

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  21. The prevalence of precocious puberty is increasing. Obesity has been demonstrated to be associated with changes in the adipokine profile and incidence of early puberty in girls. This study assessed the puberta...

    Authors: Elnaz Shokri, Ali Heidarianpour and Zahra Razavi

    Citation: Lipids in Health and Disease 2021 20:152

    Content type: Research

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  22. Acylcarnitine is an intermediate product of fatty acid oxidation. It is reported to be closely associated with the occurrence of diabetic cardiomyopathy (DCM). However, the mechanism of acylcarnitine affecting...

    Authors: Dan-meng Zheng, Zhen-ni An, Ming-hao Ge, Dong-zhuo Wei, Ding-wen Jiang, Xue-jiao Xing, Xiao-lei Shen and Chang Liu

    Citation: Lipids in Health and Disease 2021 20:151

    Content type: Research

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  23. Extremely low levels of high-density lipoprotein cholesterol (HDL-C) are related to high cardiovascular mortality. The underlying mechanism is not well known. This research aims to study the clinical character...

    Authors: Lufan Sun, Lian Duan and Dalin Jia

    Citation: Lipids in Health and Disease 2021 20:149

    Content type: Research

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  24. The prevalence of dyslipidemia in China is increasing annually. Current studies suggest that dyslipidemia affects the antiviral efficacy of hepatitis C virus (HCV) therapies, while recent studies suggest that ...

    Authors: Ziqiang Xia, Juzeng Zheng, Liang Zheng, Endian Zheng, Zhuolin Zou, Xiong Sheng and Jinming Wu

    Citation: Lipids in Health and Disease 2021 20:148

    Content type: Research

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  25. Lipid levels in blood have decreased considerably during the past decades in the general population partly due to use of statins. This study aims to investigate the trends in lipid levels between 2001 and 2018...

    Authors: Anna E. Engell, Henrik L. Jørgensen, Bent S. Lind, Anton Pottegård, Christen L. Andersen, John S. Andersen, Margit Kriegbaum, Mia K. Grand and Lise Bathum

    Citation: Lipids in Health and Disease 2021 20:147

    Content type: Research

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  26. Bladder cancer (BLCA) is a common cancer associated with an unfavorable prognosis. Increasing numbers of studies have demonstrated that lipid metabolism affects the progression and treatment of tumors. Therefo...

    Authors: Ke Zhu, Liu Xiaoqiang, Wen Deng, Gongxian Wang and Bin Fu

    Citation: Lipids in Health and Disease 2021 20:146

    Content type: Research

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  27. Non-alcoholic fatty liver disease (NAFLD) has been entitled as metabolic-dysfunction associated fatty liver disease (MAFLD). Therefore anthropometric indicators of adiposity may provide a non-invasive predicti...

    Authors: Jinwei Cai, Cuiting Lin, Shuiqing Lai, Yingshan Liu, Min Liang, Yingfen Qin, Xinghuan Liang, Aihua Tan, Yong Gao, Zheng Lu, Chunlei Wu, Shengzhu Huang, Xiaobo Yang, Haiying Zhang, Jian Kuang and Zengnan Mo

    Citation: Lipids in Health and Disease 2021 20:145

    Content type: Research

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  28. Evidence on the relationship between the low−/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) and carotid plaques remains limited. This study aimed to examine the association between LDL-C/HDL-C and c...

    Authors: Zhu Li, Qi Cheng, Yijia Liu, Xufeng Cheng, Shuo Wang, Yuanyuan He, Xu Wang, Mengnan Huang, Yue Li, Xiaoxue Xue, Yilan Xu, Lin Li, Yanchao Zheng, Rongrong Yang, Shan Gao and Chunquan Yu

    Citation: Lipids in Health and Disease 2021 20:144

    Content type: Research

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  29. Breast cancer is one of the main leading causes of women death. In recent years, attention has been focused on the role of lipoproteins, alterations of cholesterol metabolism and oxidative stress in the molecu...

    Authors: Gabriele Mazzuferi, Tiziana Bacchetti, Md Obaidul Islam and Gianna Ferretti

    Citation: Lipids in Health and Disease 2021 20:143

    Content type: Review

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  30. Effective and applicable predictors of non-alcoholic fatty liver disease (NAFLD) are needed for the non-obese Chinese population. This study was undertaken to investigate: whether serum gamma-glutamyl transfer...

    Authors: Liling Wu, Man Zhang, Haofei Hu and Qijun Wan

    Citation: Lipids in Health and Disease 2021 20:142

    Content type: Research

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  31. The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus started in March 2020. The conclusions from numerous studies indicate that people with comorbidities, such as arteri...

    Authors: Stanisław Surma, Maciej Banach and Joanna Lewek

    Citation: Lipids in Health and Disease 2021 20:141

    Content type: Review

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  32. Recent studies have substantiated the role of the triglyceride glucose (TyG) index in predicting the prognosis of coronary artery disease (CAD) patients, while no relevant studies have revealed the association...

    Authors: Ang Gao, Jinxing Liu, Chengping Hu, Yan Liu, Yong Zhu, Hongya Han, Yujie Zhou and Yingxin Zhao

    Citation: Lipids in Health and Disease 2021 20:140

    Content type: Research

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  33. Remnant cholesterol (RC) mediates the progression of coronary artery disease, diabetic complications, hypertension, and chronic kidney disease. Limited information is available on the association of RC with no...

    Authors: Yang Zou, Jianyun Lan, Yanjia Zhong, Shuo Yang, Huimin Zhang and Guobo Xie

    Citation: Lipids in Health and Disease 2021 20:139

    Content type: Research

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  34. Lipid management is the first line of treatment for decreasing the incidence of cardiovascular events in patients with coronary heart disease (CHD), and a variety of indicators are used to evaluate lipid manag...

    Authors: Jiacheng Lai, Yongsheng Han, Chongjian Huang, Bin Li, Jingshu Ni, Meili Dong, Yikun Wang and Qingtong Wang

    Citation: Lipids in Health and Disease 2021 20:137

    Content type: Research

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  35. Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and cirrhosis. NAFLD is mediated by changes in lipid metabolism and known risk factors include obesity, metabolic syndrome, ...

    Authors: Yvonne N. Flores, Aryana T. Amoon, Baolong Su, Rafael Velazquez-Cruz, Paula Ramírez-Palacios, Jorge Salmerón, Berenice Rivera-Paredez, Janet S. Sinsheimer, Aldons J. Lusis, Adriana Huertas-Vazquez, Sammy Saab, Beth A. Glenn, Folasade P. May, Kevin J. Williams, Roshan Bastani and Steven J. Bensinger

    Citation: Lipids in Health and Disease 2021 20:136

    Content type: Research

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  36. Dysregulated lipid metabolism is critically involved in the development of hepatocellular carcinoma (HCC). The respective metabolic pathways affected in HCC can be identified using suitable experimental models...

    Authors: Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler

    Citation: Lipids in Health and Disease 2021 20:135

    Content type: Research

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  37. Conicity index, body-shape index, lipid accumulation product (LAP), waist circumference (WC), triglyceride, triglyceride-glucose (TyG) index, hepatic steatosis index (HSI), waist-to-height ratio (WHtR), TyG in...

    Authors: Guotai Sheng, Song Lu, Qiyang Xie, Nan Peng, Maobin Kuang and Yang Zou

    Citation: Lipids in Health and Disease 2021 20:134

    Content type: Research

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  38. Blood lipids are essential components for cellular growth. An inverse association between serum lipid levels and risk of cancer has led to a controversy among previous studies. The aim of this prospective coho...

    Authors: Yu-Chen Chang, Chien-Ju Lin, Tzu-Lin Yeh, Ming-Chieh Tsai, Le-Yin Hsu, Kuo-Liong Chien and Hsin-Yin Hsu

    Citation: Lipids in Health and Disease 2021 20:133

    Content type: Research

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  39. The relationship between nonalcoholic fatty liver disease (NAFLD) and obesity-related indices has been analyzed separately thus far, and evidence comparing these indices together is still lacking, especially i...

    Authors: Fangfei Xie, Yuyu Pei, Quan Zhou, Deli Cao and Yun Wang

    Citation: Lipids in Health and Disease 2021 20:132

    Content type: Research

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  40. Limited studies regarding the correlation of lipid accumulation product (LAP) with a decreased estimated glomerular filtration rate (eGFR) have yielded conflicting findings, and no report has demonstrated the ...

    Authors: Pijun Yan, Yong Xu, Ying Miao, Qian Tang, Yuru Wu, Xue Bai, Zhihong Zhang, Qian Li and Qin Wan

    Citation: Lipids in Health and Disease 2021 20:131

    Content type: Research

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  41. High serum Lipoprotein(a) (Lp(a)) level and Apolipoprotein B/Apolipoprotein AΙ (ApoB/ApoA-Ι) ratio are risk factors for cardiovascular disease and kidney disease and have been found to be correlated with the p...

    Authors: Jun Tao, Wen Dai, Chenglin Ye, Qian Yao, Man Zhou and Yan Li

    Citation: Lipids in Health and Disease 2021 20:130

    Content type: Research

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  42. Mycobacterium tuberculosis (Mtb), the main etiology of tuberculosis (TB), is predominantly an intracellular pathogen that has caused infection, disease and death in humans for centuries. Lipid droplets (LDs) are ...

    Authors: Daniel Mekonnen, Awoke Derbie, Adane Mihret, Solomon Abebe Yimer, Tone Tønjum, Baye Gelaw, Endalkachew Nibret, Abaineh Munshae, Simon J. Waddell and Abraham Aseffa

    Citation: Lipids in Health and Disease 2021 20:129

    Content type: Review

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  43. Evidence suggests that proteins related to lipid metabolism, such as apolipoproteins, play an important role in the maintenance of normal vision. While several members of the apolipoprotein family are abundant...

    Authors: Parth A. Patel, Tae Jin Lee, Sai Karthik Kodeboyina, Garrett Jones, Kathryn Bollinger, Lane Ulrich, David Bogorad, Amy Estes, Wenbo Zhi, Shruti Sharma and Ashok Sharma

    Citation: Lipids in Health and Disease 2021 20:128

    Content type: Research

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  44. Coronary artery disease (CAD) is a common cardiovascular disease, and abnormal blood lipid metabolism is an important risk factor. Transforming growth factor-ß (TGF-ß) and its receptor (TGF-ßR) can inhibit the...

    Authors: Haibin Chen, Yiping Wang, Bing Sun, Xunxia Bao, Yu Tang, Feifei Huang, Sibo Zhu and Jiahong Xu

    Citation: Lipids in Health and Disease 2021 20:127

    Content type: Research

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  45. The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). At present, the COVID-19 has been prevalent worldwide for more than a year and caused...

    Authors: Yanlan Xu, Xinyu Yang, Hua Bian and Mingfeng Xia

    Citation: Lipids in Health and Disease 2021 20:126

    Content type: Review

    Published on:

  46. Abnormalities in serum lipids and lipoproteins have been documented to link to the risk of cancers in recent years, but its prognostic value for cancer is not known. This study retrospectively evaluated the si...

    Authors: Cong Ma, Xiaoyan Wang, Jingjing Guo and Ping Liu

    Citation: Lipids in Health and Disease 2021 20:69

    Content type: Research

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  47. Idiopathic membranous nephropathy (IMN) may have various clinical outcomes. Hyperlipidemia is quite common in IMN. However, the utility of the lipid profile in predicting outcomes remains unknown. This study a...

    Authors: Lei Dong, Wang Wei, Min Han and Gang Xu

    Citation: Lipids in Health and Disease 2021 20:122

    Content type: Research

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