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  1. Previous studies have demonstrated that nonalcoholic fatty liver disease (NAFLD) is a significant risk factor for diabetes mellitus (DM). However, these studies did not completely determine the relationship be...

    Authors: Xiaodan Zheng, Changchun Cao, Yongcheng He, Xinyu Wang, Jun Wu and Haofei Hu

    Citation: Lipids in Health and Disease 2021 20:59

    Content type: Research

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  2. Pancreatic cancer is the fourth leading cause of cancer deaths in the United States both in females and in males, and is projected to become the second deadliest cancer by 2030. The overall 5-year survival rat...

    Authors: Rubing Bai, Artur Rebelo, Jörg Kleeff and Yoshiaki Sunami

    Citation: Lipids in Health and Disease 2021 20:58

    Content type: Research

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  3. There is a well-documented empirical relationship between lipoprotein (a) [Lp(a)] and cardiovascular disease (CVD); however, causal evidence, especially from the Chinese population, is lacking. Therefore, this...

    Authors: Juan Xia, Chunyue Guo, Kuo Liu, Yunyi Xie, Han Cao, Wenjuan Peng, Yanyan Sun, Xiaohui Liu, Bingxiao Li and Ling Zhang

    Citation: Lipids in Health and Disease 2021 20:57

    Content type: Research

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  4. Proprotein convertase subtilisin/kexin type 9 (Pcsk9) correlated with incidence and prognosis of coronary heart disease. However, it is unclear whether Pcsk9 contributed to coronary artery lesion severity in p...

    Authors: Jing Gao, Ya-Nan Yang, Zhuang Cui, Si-Yuan Feng, Jing Ma, Chang-Ping Li and Yin Liu

    Citation: Lipids in Health and Disease 2021 20:56

    Content type: Research

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  5. Angiopoietin-like proteins (ANGPTLs) are closely related to insulin resistance and lipid metabolism, and may be a key in metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) (newly named metabolic-ass...

    Authors: Yani Ke, Shan Liu, Zheyuan Zhang and Jie Hu

    Citation: Lipids in Health and Disease 2021 20:55

    Content type: Review

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  6. Nonalcoholic fatty liver disease (NAFLD) has become one of the most common chronic liver diseases worldwide. Triglyceride (TG) accumulation is central to NAFLD development. People now spend most of their day i...

    Authors: Xiaoyu Hou, Yunpeng Guan, Yong Tang, An Song, Jiajun Zhao, Luping Ren, Shuchun Chen, Limin Wei, Huijuan Ma and Guangyao Song

    Citation: Lipids in Health and Disease 2021 20:54

    Content type: Research

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  7. The association of circulating lipids with breast cancer is being debated. The objective of this study was to examine the relationship between abnormal plasma lipids and breast cancer risk in Bangladeshi women.

    Authors: Fatama Akter Chowdhury, Md Faridul Islam, Mahnaz Tabassum Prova, Mahbuba Khatun, Iffat Sharmin, Kazi Mazharul Islam, Md. Kamrul Hassan, Md. Abdullah Saeed Khan and Mohammed Mostafizur Rahman

    Citation: Lipids in Health and Disease 2021 20:52

    Content type: Research

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  8. The albumin-to-alkaline phosphatase ratio (AAPR) is a newly developed index of liver function, but its association in patients with non-alcoholic fatty liver disease (NAFLD) has not been established. The aim o...

    Authors: Guotai Sheng, Nan Peng, Chong Hu, Ling Zhong, Mingchun Zhong and Yang Zou

    Citation: Lipids in Health and Disease 2021 20:50

    Content type: Research

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  9. The triglyceride glucose (TyG) index is a noninsulin-based marker for insulin resistance (IR) in general practice. Although smoking and heavy drinking have been regarded as major risk factors for various chron...

    Authors: Wonhee Baek, Ji-Won Lee, Hye Sun Lee, Donghee Han, Su-Yeon Choi, Eun Ju Chun, Hae-Won Han, Sung Hak Park, Jidong Sung, Hae Ok Jung, Hyangkyu Lee and Hyuk-Jae Chang

    Citation: Lipids in Health and Disease 2021 20:49

    Content type: Research

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  10. Numerous studies have revealed the relationship between lipid expression and increased cardiovascular risk in ST-segment elevation myocardial infarction (STEMI) patients. Nevertheless, few investigations have ...

    Authors: Yuzhou Xue, Jian Shen, Weifeng Hong, Wei Zhou, Zhenxian Xiang, Yuansong Zhu, Chuiguo Huang and Suxin Luo

    Citation: Lipids in Health and Disease 2021 20:48

    Content type: Research

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  11. Scleroedema adultorum of Buschke is a rare disorder characterized by fibromucinous thickening of the dermis that manifests mainly at the nape of the neck and on the upper back and shoulders. This study screene...

    Authors: Viktória Csonka, Beáta Bódis, Dániel Kovács, Nelli Farkas, Endre Kálmán, László Czirják and Cecília Varjú

    Citation: Lipids in Health and Disease 2021 20:47

    Content type: Research

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  12. Sampson et al. developed a novel method to estimate very low-density lipoprotein cholesterol (VLDL-C) and low-density lipoprotein cholesterol (LDL-C) in the setting of hypertriglyceridemia. Familial Combined H...

    Authors: Arsenio Vargas-Vázquez, Omar Yaxmehen Bello-Chavolla, Neftali Eduardo Antonio-Villa, Roopa Mehta, Ivette Cruz-Bautista and Carlos A. Aguilar-Salinas

    Citation: Lipids in Health and Disease 2021 20:46

    Content type: Research

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  13. Although patients with familial heterozygous hypercholesterolemia (FH) have a high risk of early myocardial infarction (MI), the coronary artery disease (CAD) burden in FH patients with acute MI remains to be ...

    Authors: Hermann Yao, Michel Farnier, Laura Tribouillard, Frédéric Chague, Philippe Brunel, Maud Maza, Damien Brunet, Luc Rochette, Florence Bichat, Yves Cottin and Marianne Zeller

    Citation: Lipids in Health and Disease 2021 20:45

    Content type: Research

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  14. Johann Ludwig Wilhelm Thudicum described sphingolipids (SLs) in the late nineteenth century, but it was only in the past fifty years that SL research surged in importance and applicability. Currently, sphingol...

    Authors: Muna Abed Rabbo, Yara Khodour, Laurie S. Kaguni and Johnny Stiban

    Citation: Lipids in Health and Disease 2021 20:44

    Content type: Review

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  15. Waist circumference (WC) and uric acid (UA) are significantly related. Still, their temporal sequence and how the sequence works on future risk of triglyceride glucose (TyG) are unknown, especially in the Chin...

    Authors: Jia Zheng, Min Jiang and Yanxia Xie

    Citation: Lipids in Health and Disease 2021 20:42

    Content type: Research

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  16. Recently, several novel scoring systems have been developed to evaluate the severity and outcomes of acute pancreatitis. This study aimed to compare the effectiveness of novel and conventional scoring systems ...

    Authors: Qing Wu, Jie Wang, Mengbin Qin, Huiying Yang, Zhihai Liang and Guodu Tang

    Citation: Lipids in Health and Disease 2021 20:41

    Content type: Research

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  17. Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with mitochondrial damages. However, the exact mechanisms involved in the etiology of the disease are not clear.

    Authors: Yan Jiang, Duankai Chen, Qiming Gong, Qunqing Xu, Dong Pan, Feiyan Lu and Qianli Tang

    Citation: Lipids in Health and Disease 2021 20:40

    Content type: Research

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  18. To investigate the roles of the transcription factors twist family bHLH transcription factor 1 (TWIST1), twist family bHLH transcription factor 2 (TWIST2), and peroxisome proliferator activated receptor gamma ...

    Authors: Yanmei Zhang, Xiaoxiao Ge, Yongqing Li, Bingyang Zhang, Peijun Wang, Mingju Hao, Peng Gao, Yueyi Zhao, Tao Sun, Sumei Lu and Wanshan Ma

    Citation: Lipids in Health and Disease 2021 20:39

    Content type: Research

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  19. Neonatal severe hypertriglyceridemia is rarely reported in the literature and there is no consensus for hypertriglyceridemia management at this age group.

    Authors: Nehal M. El-koofy, Yasmeen A. Abdo, Dina El-Fayoumi, Amanne F. Esmael, Mohamed. A. Elmonem and Zahraa Ezzeldin

    Citation: Lipids in Health and Disease 2021 20:38

    Content type: Research

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  20. Some observational studies have found a significant association between the use of statin and a reduced risk of dementia. However, the results of these studies are unclear in patients with rheumatoid arthritis...

    Authors: Tsung-Kun Lin, Jing-Yang Huang, Lung-Fa Pan and Gwo-Ping Jong

    Citation: Lipids in Health and Disease 2021 20:37

    Content type: Research

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  21. Several studies have found that a low baseline low -density lipoprotein cholesterol (LDL-C) concentration was associated with poor prognosis in patients with acute coronary syndrome (ACS), which is called the ...

    Authors: Bo Wang, Jin Liu, Shiqun Chen, Ming Ying, Guanzhong Chen, Liwei Liu, Zhubin Lun, Huanqiang Li, Haozhang Huang, Qiang Li, Yaren Yu, Mengfei Lin, Wen Wei, Zhidong Huang, Yongquan Yang, Jiyan Chen…

    Citation: Lipids in Health and Disease 2021 20:36

    Content type: Research

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  22. The inflammatory response plays essential roles in the pathological process and prognosis of Parkinson’s disease (PD). This research investigated the predictive value of the neutrophil to high-density lipoprot...

    Authors: Zhu Liu, Qingli Fan, Shizheng Wu, Yaqi Wan and Yancheng Lei

    Citation: Lipids in Health and Disease 2021 20:35

    Content type: Research

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  23. Polycystic ovary syndrome (PCOS) is associated with obesity, diabetes, and insulin resistance. The circulating C1Q/TNF-related proteins (CTRP-2, CTRP-9) and growth differentiation factors (GDF-8, GDF-15) contr...

    Authors: Jayakumar Jerobin, Manjunath Ramanjaneya, Ilham Bettahi, Raihanath Parammal, Kodappully Sivaraman Siveen, Meis Alkasem, Myint Aye, Thozhukat Sathyapalan, Monica Skarulis, Stephen L. Atkin and Abdul Badi Abou-Samra

    Citation: Lipids in Health and Disease 2021 20:34

    Content type: Research

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  24. Cardiovascular disease (CVD) is a major cause of mortality and morbidity within the Asia-Pacific region, with the prevalence of CVD risk factors such as plasma lipid disorders increasing in many Asian countrie...

    Authors: Zhen-Vin Lee, Elmer Jasper Llanes, Renan Sukmawan, Nuntakorn Thongtang, Huynh Quang Tri Ho and Philip Barter

    Citation: Lipids in Health and Disease 2021 20:33

    Content type: Review

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  25. Lysophosphatidic acid (LPA) is a bioactive lysophospholipid that acts through its six cognate G protein-coupled receptors. As a family, lysophospholipids have already produced medicines (e.g., sphingosine 1-phosp...

    Authors: Manisha Ray, Yasuyuki Kihara, Darryl J. Bornhop and Jerold Chun

    Citation: Lipids in Health and Disease 2021 20:32

    Content type: Short report

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  26. Hyperhomocysteinemia (HHcy) is associated with various health problems, but less is known about the gender differences in risk factors for high plasma homocysteine (Hcy) levels.

    Authors: Jing Zhao, Zhihua Li, Chengbei Hou, Fei Sun, Jing Dong, Xi Chu and Yansu Guo

    Citation: Lipids in Health and Disease 2021 20:31

    Content type: Research

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  27. Developing an understanding of the biochemistry of aging in both sexes is critical for managing disease throughout the lifespan. Lipidomic associations with age and sex have been reported, but prior studies ar...

    Authors: Emily Slade, Marguerite R. Irvin, Kevin Xie, Donna K. Arnett, Steven A. Claas, Tobias Kind, David W. Fardo and Gregory A. Graf

    Citation: Lipids in Health and Disease 2021 20:30

    Content type: Research

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  28. This study aimed to investigate the prevalence, awareness, treatment, and control rates of dyslipidemia and identify the predictors of optimal control (low-density lipoprotein cholesterol < 100 mg/dL) among pa...

    Authors: Seung Jae Kim, Oh. Deog Kwon and Kyung-Soo Kim

    Citation: Lipids in Health and Disease 2021 20:29

    Content type: Research

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  29. Low-density lipoprotein to high density lipoprotein (LDL/HDL) cholesterol ratio has been reported to predict the risk of many metabolic diseases. However, the association between the LDL/HDL cholesterol ratio ...

    Authors: Yang Zou, Ling Zhong, Chong Hu, Mingchun Zhong, Nan Peng and Guotai Sheng

    Citation: Lipids in Health and Disease 2021 20:28

    Content type: Research

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  30. The performance of liver stiffness measurements (LSMs) obtained using FibroScan can be affected by several factors, and cut-off values are different for fibrosis caused by various aetiologies. The study aims t...

    Authors: Xinyu Yang, Xinxia Chang, Shengdi Wu, Xiaoyang Sun, Xiaopeng Zhu, Liu Wang, Yushan Xu, Xiuzhong Yao, Shengxiang Rao, Xiqi Hu, Mingfeng Xia, Hua Bian, Hongmei Yan and Xin Gao

    Citation: Lipids in Health and Disease 2021 20:27

    Content type: Research

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  31. To investigate the correlation between the thickness of epicardial adipose tissue (EAT), C-reactive protein (CRP), interleukin (IL) -6, visfatin, juxtaposed with another zinc finger protein 1 (JAZF1) and type ...

    Authors: Yuan-Yuan Gong and Hai-Ying Peng

    Citation: Lipids in Health and Disease 2021 20:25

    Content type: Research

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  32. Dietary sphingolipids have various biofunctions, including skin barrier improvement and anti-inflammatory and anti-carcinoma properties. Long-chain bases (LCBs), the essential backbones of sphingolipids, are e...

    Authors: Daisuke Mikami, Shota Sakai, Megumi Nishimukai, Kohei Yuyama, Katsuyuki Mukai and Yasuyuki Igarashi

    Citation: Lipids in Health and Disease 2021 20:24

    Content type: Research

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  33. Although imbalanced intestinal flora contributes to the pathogenesis of nonalcoholic fatty liver disease (NAFLD), conflicting results have been obtained for patient-derived microbiome composition analyses. A m...

    Authors: Fuxi Li, Junzhao Ye, Congxiang Shao and Bihui Zhong

    Citation: Lipids in Health and Disease 2021 20:22

    Content type: Research

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  34. PCSK9 monoclonal antibody lowers plasma PCSK9 and LDL-cholesterol levels. The manufacturers recommend drug storage at 2–8 °C, and not above 25 °C. This study aimed to investigate drug stability at various temp...

    Authors: Tanawan Kongmalai, Nalinee Chuanchaiyakul, Chattip Sripatumtong, Tunsuda Tansit, Yuttana Srinoulprasert, Nareerak Klinsukon and Nuntakorn Thongtang

    Citation: Lipids in Health and Disease 2021 20:21

    Content type: Research

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  35. High-density lipoprotein cholesterol (HDL-C) hypolipidemia, a major type of dyslipidemia, has been associated with many kinds of diseases, such as stroke, coronary heart disease, obesity and diabetes, and has ...

    Authors: Fang Tang, Jian Wang, Stephen Nicholas, Dongfu Qian and Rugang Liu

    Citation: Lipids in Health and Disease 2021 20:20

    Content type: Research

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  36. Poor cholesterol efflux capacity (CEC) has been proposed to be an independent risk factor for cardiovascular diseases. However, current evidence is inconsistent, especially in rheumatoid arthritis (RA) patient...

    Authors: Binbin Xie, Jiang He, Yong Liu, Ting Liu and Chaoqun Liu

    Citation: Lipids in Health and Disease 2021 20:18

    Content type: Research

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  37. Pemafibrate, a selective PPARα modulator, has the beneficial effects on serum triglycerides (TGs) and very low density lipoprotein (VLDL), especially in patients with diabetes mellitus or metabolic syndrome. H...

    Authors: Ichiro Komiya, Akira Yamamoto, Suguru Sunakawa and Tamio Wakugami

    Citation: Lipids in Health and Disease 2021 20:17

    Content type: Research

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  38. Psoriasis is a common chronic inflammatory skin disease associated with overproduction of interleukin-17A (IL-17A). IL-17A monoclonal antibodies (mAbs) have shown clinical efficacy in psoriasis patients. Altho...

    Authors: Han Cao, Shengmin Su, Qi Yang, Yunchen Le, Lihong Chen, Mengyan Hu, Xiaoyu Guo, Jie Zheng, Xia Li and Yunqiu Yu

    Citation: Lipids in Health and Disease 2021 20:16

    Content type: Research

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  39. The association of circulating lipids with clinical outcomes of drug-resistant castration-resistant prostate cancer (DR-CRPC) is not fully understood. While it is known that increases in select lipids correlat...

    Authors: Lishann M. Ingram, Morgan C. Finnerty, Maryam Mansoura, Chau-Wen Chou and Brian S. Cummings

    Citation: Lipids in Health and Disease 2021 20:15

    Content type: Research

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  40. Familial hypertriglyceridemia (FHTG) is a partially characterized primary dyslipidemia which is frequently confused with other forms hypertriglyceridemia. The aim of this work is to search for specific feature...

    Authors: Ivette Cruz-Bautista, Alicia Huerta-Chagoya, Hortensia Moreno-Macías, Rosario Rodríguez-Guillén, María Luisa Ordóñez-Sánchez, Yayoi Segura-Kato, Roopa Mehta, Paloma Almeda-Valdés, Lizeth Gómez-Munguía, Ximena Ruiz-De Chávez, Ximena Rosas-Flota, Arali Andrade-Amado, Bárbara Bernal-Barroeta, María Guadalupe López-Carrasco, Luz Elizabeth Guillén-Pineda, Angelina López-Estrada…

    Citation: Lipids in Health and Disease 2021 20:14

    Content type: Research

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  41. Dyslipidemia contributes to the pathogenesis of renal dysfunction. Previous research demonstrated that triglycerides (TG), instead of other individual lipid indexes, has a significant link with elevated urinar...

    Authors: Jing Xue, Yuxia Wang, Bing Li, Songyan Yu, Anping Wang, Weiqing Wang, Zhengnan Gao, Xulei Tang, Li Yan, Qin Wan, Guijun Qin, Lulu Chen, Guang Ning and Yiming Mu

    Citation: Lipids in Health and Disease 2021 20:13

    Content type: Research

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  42. Lipoprotein-associated Phospholipase A2 (Lp-PLA2), can exert proinflammatory as well as proatherogenic properties on the vascular wall. The current study sought to evaluate the influence of high Lp-PLA2 levels...

    Authors: Konstantinos Mourouzis, Gerasimos Siasos, Evangelos Oikonomou, Marina Zaromitidou, Vicky Tsigkou, Alexis Antonopoulos, Evanthia Bletsa, Panagiota Stampouloglou, Konstantinos Vlasis, Manolis Vavuranakis and Dimitris Tousoulis

    Citation: Lipids in Health and Disease 2021 20:12

    Content type: Research

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  43. Few studies have developed risk models for dyslipidaemia, especially for rural populations. Furthermore, the performance of genetic factors in predicting dyslipidaemia has not been explored. The purpose of thi...

    Authors: Miaomiao Niu, Liying Zhang, Yikang Wang, Runqi Tu, Xiaotian Liu, Jian Hou, Wenqian Huo, Zhenxing Mao, Zhenfei Wang and Chongjian Wang

    Citation: Lipids in Health and Disease 2021 20:11

    Content type: Research

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