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Table 1 Serum lipid profile in mice fed a high fat diet

From: Effects of simvastatin on apolipoprotein M in vivo and in vitro

Lipids

(mmol/L)

 

Control diet

  

High fat diet

 
 

12 weeks

20 weeks

P

12 weeks

20 weeks

P

TC

2.44 ± 0.22

2.64 ± 0.20

P > 0.05

2.97 ± 0.09

4.89 ± 0.18

P < 0.0001

LDL-C

0.40 ± 0.03

0.40 ± 0.02

P > 0.05

0.47 ± 0.01

0.99 ± 0.05

P < 0.0001

HDL-C

TG

1.53 ± 0.10

1.53 ± 0.10

1.61 ± 0.12

1.67 ± 0.15

P > 0.05

P > 0.05

1.73 ± 0.06

1.57 ± 0.07

1.69 ± 0.06

0.98 ± 0.04

P > 0.05

P < 0.0001

  1. Data are shown as means ± SEM. TC (total cholesterol), HDL-C (high density lipoprotein cholesterol), LDL-C (low density lipoprotein cholesterol), TG (triglyceride).
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Lipids in Health and Disease

ISSN: 1476-511X