Table 1 Body weight, fasting plasma glucose and lipid metabolites in Chinese Bama minipigs

Body weight (kg)

CD

6.04 ± 1.24

9.22 ± 1.29

10.28 ± 1.51

12.34 ± 1.73

14.35 ± 2.14

16.85 ± 3.74

HSFD

6.04 ± 2.12

8.90 ± 2.68

10.76 ± 2.61

14.18 ± 4.25

18.50 ± 5.31 *

23.55 ± 7.46 **

HSFD+Ibrolipim

6.02 ± 1.10

8.48 ± 1.65

10.08 ± 1.84

13.02 ± 2.50

14.40 ± 2.51 ^#

16.56 ± 3.83 ^##

Glucose (mmol/l)

CD

4.71 ± 0.39

4.24 ± 0.90

4.83 ± 0.87

5.24 ± 1.00

4.65 ± 0.71

4.77 ± 0.57

HSFD

5.12 ± 0.84

5.97 ± 0.73 *

6.88 ± 0.57 *

8.89 ± 2.05 **

9.54 ± 2.12 **

10.27 ± 2.25 **

HSFD+Ibrolipim

4.78 ± 0.62

4.41 ± 1.45

4.96 ± 1.09 ^#

5.89 ± 0.50 ^#

4.85 ± 1.10 ^##

4.75 ± 0.45 ^##

Insulin (U/l)

CD

6.97 ± 0.33

7.31 ± 0.94

7.50 ± 0.93

8.68 ± 0.82

7.25 ± 0.80

7.65 ± 1.33

HSFD

7.47 ± 1.16

9.12 ± 1.63

15.12 ± 3.22 *

21.16 ± 5.08 *

24.43 ± 3.55 **

17.43 ± 3.80 **

HSFD+Ibrolipim

7.65 ± 0.91

8.73 ± 1.52

9.43 ± 0.84 ^#

10.95 ± 2.95 ^#

10.30 ± 3.57 ^##

10.34 ± 2.71 ^#

Homeostatic model assessment

CD

1.38 ± 0.18

1.54 ± 0.50

1.63 ± 0.47

1.97 ± 0.63

1.51 ± 0.32

1.64 ± 0.45

HSFD

1.59 ± 0.26

2.29 ± 0.39

4.38 ± 1.05 **

7.04 ± 1.05 **

10.40 ± 1.75 **

7.83 ± 1.63 **

HSFD+Ibrolipim

1.56 ± 0.26

1.87 ± 0.56

2.11 ± 0.59 ^##

2.89 ± 0.51 ^##

2.16 ± 0.45 ^##

2.62 ± 0.70 ^##

Triglyceride (mmol/l)

CD

0.59 ± 0.04

0.59 ± 0.06

0.63 ± 0.10

0.69 ± 0.16

0.71 ± 0.15

0.73 ± 0.13

HSFD

0.59 ± 0.05

0.94 ± 0.07 **

1.50 ± 0.18 **

1.87 ± 0.14 **

2.03 ± 0.42 **

2.10 ± 0.32 **

HSFD+Ibrolipim

0.58 ± 0.04

0.60 ± 0.01 ^#

0.78 ± 0.08 ^##

0.87 ± 0.17 ^##

1.03 ± 0.25 ^##

1.10 ± 0.35 ^##

Total cholesterol (mmol/l)

CD

2.06 ± 0.34

1.99 ± 0.33

2.01 ± 0.35

1.68 ± 0.21

1.82 ± 0.49

2.07 ± 0.46

HSFD

2.31 ± 0.44

6.24 ± 1.77 **

9.06 ± 1.44 **

11.20 ± 2.02 **

15.23 ± 2.00 **

20.45 ± 2.83 **

HSFD+Ibrolipim

2.29 ± 0.55

8.02 ± 2.15 ^#

11.99 ± 2.15 ^#

13.55 ± 3.12 ^#

16.39 ± 4.23

22.14 ± 4.59

HDL cholesterol (mmol/l)

CD

0.78 ± 0.14

0.76 ± 0.18

0.85 ± 0.17

1.02 ± 0.12

0.81 ± 0.16

0.96 ± 0.29

HSFD

0.89 ± 0.12

1.09 ± 0.18 *

1.37 ± 0.28 *

1.82 ± 0.53 *

2.00 ± 0.39 **

1.83 ± 0.36 **

HSFD+Ibrolipim

0.79 ± 0.15

1.23 ± 0.21

2.29 ± 0.43 ^##

2.85 ± 0.47 ^##

2.92 ± 0.54 ^##

2.86 ± 0.46 ^##