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Table 2 Body weights, food intakes, organ weights and plasma lipid levels.

From: Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes

 

Control

C16:0

C16:1

Initial body weight (g)

30.0 ± 0.3

30.1 ± 0.3

30.8 ± 0.4

Final body weight (g)

36.7 ± 0.5a

35.3 ± 0.7a

32.1 ± 1.1b

Food intake (g/day)

6.1 ± 0.1a

5.8 ± 0.2a

5.1 ± 0.3b

Organ weights

   

   Liver (mg/g BW)

46.9 ± 1.3a

46.3 ± 1.3a

40.2 ± 0.9b

   Pancreas (mg/g BW)

9.6 ± 0.2a

10.2 ± 0.2a

11.2 ± 0.3b

   Mesenteric WAT (mg/g BW)

21.2 ± 0.9

21.1 ± 0.4

19.1 ± 1.2

   BAT (mg/g BW)

7.2 ± 0.5

7.1 ± 0.4

7.6 ± 0.4

   Skeletal muscle (mg/g BW)

8.8 ± 0.3

8.6 ± 0.3

9.1 ± 0.5

Plasma lipid parameters

   

   Triglyceride (mg/dL)

259.2 ± 21.1a

237.3 ± 15.7a

129.1 ± 23.7b

   Total cholesterol (mg/dL)

112.7 ± 8.2

99.4 ± 5.9

109.7 ± 4.6

   Free fatty acid (mEq/L)

0.49 ± 0.03

0.48 ± 0.02

0.48 ± 0.03

  1. KK-Ay mice were orally administrated vehicle (control), 300 mg/kg of palmitic acid, or 300 mg/kg palmitoleic acid on a daily basis for 4 weeks. Values are means ± SE, n = 10. Means in a row with superscripts without common letter are different, p < 0.05. C16:0, palmitic acid; C16:1, palmitoleic acid; BW, body weight; WAT, white adipose tissue; BAT, brown adipose tissue.