Figure 1From: Native low density lipoprotein induces pancreatic β cell apoptosis through generating excess reactive oxygen speciesLDLs induce the apoptosis of MIN6sThe MIN6 cells were exposed to LDLs with indicated concentrations for 48 hours. The cell images were obtained with a phase-contrast microscope at 48 hours after the exposure. Bar, 25 μm (a). The numbers of adherent cells were expressed as percentage of the number of control cells (b). Mean ± SD (n = 3). *: p < 0.05 vs. the levels of control cells (b and c). DNA fragmentation was analyzed by the TUNEL method at 24 h after LDLs exposure. Representative images are shown. Bar, 25 μm (d). The fold increase in TUNEL positive cells above the control (LDLs-unloaded cells is shown in Figure e. *: p < 0.05.Back to article page