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Figure 1 | Lipids in Health and Disease

Figure 1

From: Native low density lipoprotein induces pancreatic β cell apoptosis through generating excess reactive oxygen species

Figure 1

LDLs induce the apoptosis of MIN6sThe MIN6 cells were exposed to LDLs with indicated concentrations for 48 hours. The cell images were obtained with a phase-contrast microscope at 48 hours after the exposure. Bar, 25 μm (a). The numbers of adherent cells were expressed as percentage of the number of control cells (b). Mean ± SD (n = 3). *: p < 0.05 vs. the levels of control cells (b and c). DNA fragmentation was analyzed by the TUNEL method at 24 h after LDLs exposure. Representative images are shown. Bar, 25 μm (d). The fold increase in TUNEL positive cells above the control (LDLs-unloaded cells is shown in Figure e. *: p < 0.05.

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