Genetic variant of V825I in the ATP-binding cassette transporter A1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Cao, Xiao-Li; Yin, Rui-Xing; Wu, Dong-Feng; Miao, Lin; Aung, Lynn Htet Htet; Hu, Xi-Jiang; Li, Qing; Yan, Ting-Ting; Lin, Wei-Xiong; Pan, Shang-Ling

doi:10.1186/1476-511X-10-14

Lipids in Health and Disease

Table 5 Correlative factors for serum lipid parameters between males and females in both ethnic groups

From: Genetic variant of V825I in the ATP-binding cassette transporter A1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Lipid parameter	Relative factor	Standardized coefficient	Standard error	t	P
Bai Ku Yao
Male
TC	Body mass index	0.268	0.023	5.036	0.000
	Age	0.130	0.007	2.434	0.015
TG	Body mass index	0.216	0.031	3.973	0.000
HDL-C	Alcohol consumption	0.229	0.037	5.033	0.000
	Age	0.275	0.002	4.286	0.000
	Body mass index	-0.116	0.011	-0.201	0.028
LDL-C	Body mass index	0.261	0.021	4.854	0.000
ApoAI	Alcohol consumption	0.313	0.028	5.887	0.000
	Age	0.187	0.001	3.519	0.000
ApoB	Body mass index	0.293	0.006	5.496	0.000
ApoAI/ApoB	Alcohol consumption	0.272	0.068	4.983	0.000
	Body mass index	-0.188	0.022	-3.449	0.001
Female
TC	Body mass index	0.170	0.016	3.253	0.001
	Age	0.148	0.003	2.824	0.005
TG	Alcohol consumption	0.205	0.080	3.919	0.000
LDL-C	Body mass index	0.168	0.013	3.209	0.001
	Age	0.162	0.002	3.012	0.002
ApoAI	Age	0.159	0.001	2.300	0.003
	Body mass index	0.160	0.001	2.030	0.022
ApoB	Systolic blood pressure	0.328	0.008	3.067	0.002
	Body mass index	0.202	0.003	3.321	0.001
	Weight	0.025	0.117	2.053	0.041
ApoAI/ApoB	Diastolic blood pressure	-0.155	0.003	-2.937	0.004
Han Chinese
Male
TC	Weight	0.334	0.006	6.638	0.000
	Age	0.228	0.003	4.424	0.000
	Alcohol consumption	0.152	0.065	2.932	0.004
TG	Weight	0.385	0.009	7.379	0.000
HDL-C	Age	0.336	0.002	6.729	0.000
	Alcohol consumption	0.309	0.031	6.148	0.000
	Weight	-0.016	0.003	-3.278	0.007
	Genotype	-0.131	0.035	-2.711	0.000
LDL-C	Weight	0.287	0.004	5.389	0.000
	Age	0.174	0.007	3.273	0.001
ApoAI	Age	0.377	0.001	7.609	0.000
	Alcohol consumption	0.278	0.017	5.622	0.000
	Genotype	-0.125	0.020	-2.599	0.010
ApoB	Body mass index	0.295	0.004	5.718	0.000
	Age	0.208	0.001	3.930	0.000
	Smoking	0.124	0.014	2.422	0.016
	Alcohol consumption	0.106	0.015	2.005	0.046
ApoAI/ApoB	Age	0.118	0.020	2.100	0.037
	Body mass index	-0.172	0.011	-3.054	0.002
Female
TC	Age	0.278	0.007	5.317	0.000
	Weight	0.210	0.006	4.075	0.000
	Diastolic blood pressure	0.152	0.005	2.855	0.005
TG	Diastolic blood pressure	0.167	0.005	3.072	0.002
HDL-C	Age	0.198	0.002	3.658	0.000
LDL-C	Weight	0.317	0.005	6.462	0.000
	Age	0.327	0.002	6.597	0.000
	Alcohol consumption	-0.167	0.052	-3.375	0.001
ApoAI	Age	0.286	0.001	5.433	0.000
	Weight	0.117	0.002	2.220	0.027
ApoB	Body mass index	0.251	0.004	4.878	0.000
	Age	0.240	0.001	4.625	0.000
	Diastolic blood pressure	0.124	0.001	2.344	0.020
ApoAI/ApoB	Weight	-0.188	0.009	-3.463	0.001

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B.

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com