Table 1 Characteristics of n = 1402 National Heart, Lung, and Blood, Institute Family Heart Study participants, by apolipoprotein ε4 carrier status.
Carriers of ε4 | Non-carriers of ε4 | p-value | |
|---|---|---|---|
Characteristic | n = 397 (28.3%) | n = 1005 (71.7%) | |
Age, mean (SD)* | 54.9(10.9) | 57.0(11.0) | 0.001 |
Male, no. (%)* | 193(48.6) | 472(47.0) | 0.58 |
BMI, kg/m2, mean (SD)* | 28.3(5.3) | 28.4(5.6) | 0.89 |
Current smoker, no. (%) | 45(11.3) | 138(13.7) | 0.23 |
≥ 2 alcoholic drinks daily, no. (%) | 197(49.6) | 497 (49.5) | 0.95 |
Monounsaturated fat intake, g/day, mean (SD) | 24.7(13.9) | 23.3(12.5) | 0.06 |
Polyunsaturated fat intake, g/day, mean (SD) | 9.1(5.1) | 8.7(4.6) | 0.17 |
Exercise in minutes/day, mean (SD) | 26.8(37.3) | 28.2(34.7) | 0.51 |
HDL, mg/dL, mean (SD)* | 45.8(14.1) | 49.1(15.8) | 0.0003 |
LDL, mg/dL, mean (SD) | 132.8(37.0) | 128.8(35.5) | 0.06 |
Triglycerides, mg/dL, mean (SD) | 178.7(102.0) | 164.4(109.3) | 0.03 |
Diabetes mellitus, no. (%) | 27(6.8) | 95(9.5) | 0.11 |
Hypertension, no. (%) | 116(29.2) | 364(36.2) | 0.01 |
Coronary heart disease, no. (%) | 72(18.1) | 176(17.5) | 0.78 |
Angina, no. (%) | 46(11.6) | 150(14.9) | 0.10 |
Stroke, no. (%) | 13(3.3) | 35(3.5) | 0.85 |
Cancer, no. (%) | 45(11.3) | 111(11.0) | 0.88 |