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Table 8 The effect of feeding growing female rats different sources of omega-3 fatty acids on oxidative stability and eicosanoid metabolism

From: Different sources of omega-3 polyunsaturated fatty acids affects apparent digestibility, tissue deposition, and tissue oxidative stability in growing female rats

  

Treatments

 

Measurements1

CO

FO

KO

MO

SO

TO

Eicosanoids

      

PGE2 metabolite (μg/d)

2.2 ± 1.5

1.7 ± 1.1

4.6 ± 2.1

0.9 ± 0.04

1.3 ± 1.0

1.1 ± 0.3

TXB2 metabolite (μg/d)

1474 ± 665

991 ± 393

1653 ± 447

807 ± 248

1972 ± 808

1359 ± 431

Oxidative Stability

      

RBC TBARS (μM MDA/mL)

9.5 ± 0.6

9.2 ± 0.60

8.5 ± 0.2

9.4 ± 0.5

10.0 ± 0.6

9.6 ± 0.2

Serum TBARS (μM MDA/mL)

6.9 ± 0.4a

5.9 ± 0.2ab

6.5 ± 0.3a

6.8 ± 0.3a

5.1 ± 0.3b

5.2 ± 0.2b

Serum TAC(mM Trolox)

1.5 ± 0.2

1.1 ± 0.1

1.3 ± 0.1

1.5 ± 0.2

1.1 ± 0.2

1.2 ± 0.2

Liver TBARS (μM MDA/g Tissue)

220.3 ± 23.8b

235.6 ± 21.7b

265.1 ± 46.4b

435.0 ± 68.8a

198.3 ± 23.3b

177.5 ± 14.7b

Liver TAC (mM Trolox)

3832 ± 421ab

4203 ± 207ab

3542 ± 726b

5695 ± 727a

2726 ± 250b

2493 ± 195b

  1. 1Values are expressed as the mean ± SEM of n = 7 rats/group. Different superscript letters a, b within the same rows indicate significant differences at P < 0.05 by one-way ANOVA followed by Tukey's test. Abbreviations are CO, corn oil; FO, flaxseed oil; KO, krill oil; MO, menhaden oil; SO, salmon oil; TO, tuna oil; PGE2 , prostaglandin E2; TXB2, thromboxane B2; RBC, red blood cells; TBARS, thiobarbituric acid reactive substances; MDA, malondialdehyde; TAC, total antioxidant capacity.