Figure 1From: Hypercholesterolemia promotes early renal dysfunction in apolipoprotein E-deficient miceRenal functional parameters in young and adult C57 and ApoE mice. Creatinine clearance (A) and serum urea (B) were used to determine the renal function in young (2-month-old) and adult (8-month-old) C57BL/6 (C57) and apolipoprotein E-deficient (ApoE) mice. Values indicate means ± SEM of the number of animals in parentheses. *p < 0.05 and **p < 0.01 vs C57 and †p < 0.05 vs 2-month-old (2-way ANOVA).Back to article page