Figure 2
From: The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit
The effect of isolated rabbit HDL on adhesion molecule expression and NF-κB activation in HCAECs. HCAECs were pre-incubated for 24 hrs with rHDL or HDL isolated from the plasma of rabbits injected with either saline, rHDL or ETC-642 (n = 10), then stimulated with TNF-α (1 ng/ml) for 5 hrs. ICAM-1, VCAM-1 and p65 mRNA levels were quantified as described in "Materials and Methods". Results expressed as mean ± SEM from triplicate in vitro experiments. *p < 0.05 and **p < 0.01, compared to TNF-α stimulated control cells.