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Figure 4 | Lipids in Health and Disease

Figure 4

From: M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

Figure 4

oxLDL-induced upregulation of the UPR target genes BiP and CHOP in THP1-derived monocyte-macrophage cell-types. Semi-quantitative determination of BiP (A) and CHOP (B) mRNA levels in THP1-Mon (white bars), THP1-M2Mon (light grey bars), dTHP1-MΦ (dark grey bars) and dTHP1-M2MΦ (black bars), after treatment with oxLDL (1 μg/ml or 40 μg/ml; 24 h) as indicated. n ≥ 3 in all cases; P < 0.05 where indicated.

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Lipids in Health and Disease

ISSN: 1476-511X