Association of the TRIB1 tribbles homolog 1 gene rs17321515 A>G polymorphism and serum lipid levels in the Mulao and Han populations

Aung, Lynn Htet Htet; Yin, Rui-Xing; Wu, Dong-Feng; Li, Qing; Yan, Ting-Ting; Wang, Yi-Ming; Li, Hui; Wei, Dai-Xun; Shi, Yuan-Lu; Yang, De-Zhai

doi:10.1186/1476-511X-10-230

Lipids in Health and Disease

Table 5 Correlative factors for serum lipid parameters between males and females in both ethnic groups

From: Association of the TRIB1 tribbles homolog 1 gene rs17321515 A>G polymorphism and serum lipid levels in the Mulao and Han populations

Lipid parameter	Risk factor	Unstandardized coefficient	Standard error	Standardized coefficient	t	P
Mulao
Male
TC	Body mass index	0.061	0.027	0.128	2.225	0.027
	Alcohol consumption	0.205	0.095	0.124	2.161	0.031
TG	Body mass index	0.165	0.054	0.172	3.044	0.003
	Alcohol consumption	0.468	0.189	0.140	2.475	0.014
	Genotype	0.519	0.246	0.119	2.110	0.036
HDL-C	Body mass index	-0.041	0.009	-0.256	-4.679	0.000
	Alcohol consumption	0.135	0.030	0.244	4.459	0.000
	Genotype	-0.098	0.039	-0.135	-2.485	0.014
ApoA1	Alcohol consumption	0.143	0.026	0.305	5.579	0.000
	Blood glucose level	-0.032	0.013	-0.135	-2.473	0.014
ApoB	Body mass index	0.021	0.011	0.114	1.984	0.048
ApoA1/ApoB	Alcohol consumption	0.167	0.041	0.225	4.094	0.000
	Body mass index	-0.049	0.012	-0.232	-4.228	0.000
	Blood glucose level	-0.057	0.020	-0.152	-2.768	0.006
Female
TC	Body mass index	0.061	0.021	0.157	2.926	0.004
	Age	0.122	0.047	0.138	2.571	0.011
TG	Body mass index	0.053	0.013	0.212	3.970	0.000
HDL-C	Body mass index	-0.036	0.007	-0.267	-5.074	0.000
LDL-C	Body mass index	0.071	0.016	0.235	4.470	0.000
	Age	0.099	0.036	0.144	2.742	0.006
ApoA1	Diastolic blood pressure	0.004	0.002	0.120	2.213	0.028
ApoB	Body mass index	0.031	0.008	0.210	3.956	0.000
	Age	0.036	0.018	0.108	2.039	0.042
ApoA1/ApoB	Body mass index	-0.042	0.012	-0.182	-3.420	0.001
	Age	-0.075	0.028	-0.144	-2.708	0.007
Han
Male
TC	Alcohol consumption	0.180	0.077	0.132	2.339	0.020
	Diastolic blood pressure	0.027	0.006	0.265	4.697	0.000
	Blood glucose level	0.077	0.037	0.115	2.056	0.041
TG	Body mass index	0.165	0.054	0.172	3.044	0.003
	Alcohol consumption	0.468	0.189	0.140	2.475	0.014
	Genotype	0.519	0.246	0.119	2.110	0.036
HDL-C	Body mass index	-0.027	0.006	-0.261	-4.721	0.000
	Alcohol consumption	0.129	0.027	0.263	4.759	0.000
	Allele	0.176	0.055	0.174	3.180	0.002
	Blood glucose level	-0.028	0.013	-0.117	-2.150	0.032
LDL-C	Allele	0.563	0.118	0.271	4.781	0.000
	Systolic blood pressure	0.005	0.003	0.120	2.106	0.036
	Blood glucose level	0.058	0.028	0.119	2.103	0.036
ApoA1	Alcohol consumption	0.134	0.018	0.405	7.529	0.000
	Body mass index	-0.015	0.004	-0.213	-3.955	0.000
	Genotype	0.063	0.023	0.149	2.796	0.006
ApoB	Body mass index	0.009	0.003	0.185	3.341	0.001
	Diastolic blood pressure	0.004	0.001	0.217	3.920	0.000
	Blood glucose level	0.033	0.006	0.279	5.291	0.000
	Alcohol consumption	0.035	0.013	0.142	2.647	0.009
ApoA1/ApoB	Alcohol consumption	0.098	0.028	0.188	3.479	0.001
	Body mass index	-0.039	0.006	-0.361	-6.708	0.000
	Blood glucose level	-0.057	0.014	-0.223	-4.184	0.000
Female
TC	Body mass index	0.061	0.019	0.174	3.285	0.001
	Age	0.209	0.042	0.266	5.028	0.000
TG	Body mass index	0.083	0.020	0.218	4.117	0.000
	Genotype	-0.184	0.083	-0.118	-2.228	0.027
	Blood glucose level	0.135	0.037	0.190	3.620	0.000
	Diastolic blood pressure	0.016	0.006	0.147	2.800	0.005
LDL-C	Body mass index	0.062	0.016	0.205	3.859	0.000
	Age	0.204	0.036	0.303	5.725	0.000
	Alcohol consumption	-0.533	0.199	-0.144	-2.675	0.008
ApoA1	Genotype	-0.047	0.019	-0.136	-2.471	0.014
ApoA1/ApoB	Alcohol consumption	0.305	0.107	0.153	2.851	0.005
	Body mass index	-0.047	0.009	-0.292	-5.510	0.000
	Age	-0.082	0.019	-0.227	-4.287	0.000

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B.

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ISSN: 1476-511X

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