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Table 1 Clinical parameters of donors and recipients at baseline, 6 weeks and 6 months after living-donor kidney transplantation (LDKT)#

From: Vitamin A metabolism is changed in donors after living-kidney transplantation: an observational study

  Donors Recipients
N (m/f) 20 (6/14) 20 (14/6)
Age (a) 46 (27-66) 42 (6-77)
  Baseline 6 weeks after LDKT 6 months after LDKT Baseline 6 weeks after LDKT 6 months after LDKT
eGFR (mL/min per 1.73 m2) 84 (68-139)a*** 58 (40-94)b 57 (40-88)b 8 (5-16)A 61 (24-145)B 63 (19-172)B
Proteinuria (mg/L) 47 (40-260) *** 40 (40-92) * 44 (40-105) * 544 (42-1943) 175 (37-762) 73 (45-1238)
UP/UC 0.09 (0.04-0.84) *** 0.10 (0.04-0.27) 0.09 (0.04-0.17) 0.78 (0.05-4.43)A 0.13 (0.06-0.37)B 0.10 (0.03-1.44)B
CRP (mg/dL) 0.17 (0.04-2.13) 0.34 (0.03-1.21) 0.28 (0.04-2.72) 0.21 (0.02-1.45) 0.26 (0.02-3.91) 0.22 (0.02-2.57)
Total cholesterol (mg/dL) 182 (141-279) 177 (142-289) 193 (118-269) 182 (126-353)A 193 (90-291)AB 191 (134-312)B
LDL cholesterol (mg/dL) 116 (67-214) 115 (72-211) 126 (68-188) 120 (76-240) 131 (72-222) 126 (72-204)
HDL cholesterol (mg/dL) 58 (39-94) ** 53 (36-90) 56 (35-92) 46 (29-71)A 52 (36-119)B 50 (30-78)B
Trigylcerides (mg/dL) 94 (46-298) *** 124 (64-292) ** 116 (72-397) * 230 (81-671) 207 (81-443) 179 (81-545)
ROH (μg/mL) 0.61 (0.37-0.84)a*** 0.81 (0.41-1.07)b 0.67 (0.43-1.09)b 1.46 (0.67-2.25)A 0.88 (0.38-1.79)B 1.01 (0.32-1.44)B
RBP4 (μmol/L) 1.76 (1.08-2.13)a*** 2.11 (1.02-3.38)b 2.55 (1.19-3.89)c 6.57 (3.19-8.77)A 2.80 (1.10-6.38)B 3.06 (0.99-5.23)B
TTR (μmol/L) 2.58 (0.96-5.78) *** 3.25 (0.47-5.06) 3.08 (1.91-4.99) 5.60 (2.06-8.37)A 3.51 (1.58-8.24)B 4.53 (1.05-6.38)B
apoRBP4 (%) 0.0 (0.0-8.2)a*** 8.3 (0.6-13.1)b 7.6 (0.3-9.6)b 30.7 (1.2-47.6)A 12.9 (0.8-23.4)B 10.2 (0.6-31.0)B
  1. # Data are presented as median (range). Abbreviations used: CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; HDL, high density lipoprotein; LDL, low density lipoprotein; LDKT, living-donor kidney transplantation; m/f; male/female; UP/UC, urine protein/urine creatinine ratio. Different superscripts a, b and c indicate significant differences between the different time points for donors. Different superscripts A and B indicate significant differences between the different time points for recipients. Superscripts *, ** and *** indicate significant differences between donors and recipients at the particular time point with * p < 0.05, ** p < 0.01 and *** p < 0.001.