Figure 5

Effects of HO-1 on hepatic inflammatory factors in MCD diet-induced fibrosing steatohepatitis. (A) Hepatic TNF-α mRNA levels were determined by (A1) RT-PCR and (A2) real-time quantitative PCR; (B) Hepatic interleukin-6 (IL-6) mRNA levels, determined by (B1) RT-PCR and (B2) real-time quantitative PCR; (C) Hepatic SOCS1 mRNA levels were determined by (C1) RT-PCR and (C2) real-time quantitative PCR. Data are expressed as the mean ± SD (n = 6 per group). *P < 0.001, compared with control group; ^#P < 0.05, ^##P < 0.01, compared with MCD group; ^$P < 0.05, ^$$P < 0.01, ^$$$P < 0.001, compared with MCD+ Ad-GFP group.