Table 4 Microarray analyses of RNA of livers of chickens after treatment with various compounds.
Genes down-regulated | ||||||||
|---|---|---|---|---|---|---|---|---|
# | Genes | Control | δ-T3 | Quer | Ribo | Co lac | Dexa | Description |
Inflammation | ||||||||
1 | AJ719859 | 3.33 | 2.03 | 2.42 | 1.74 | 1.93 | 1.18 | Proteasome (prosome, macropain) activator subunit 4 |
2 | BX950555 | 4.01 | 4.11 | 4.38 | 3.78 | 3.38 | 1.64 | Tumor necrosis factor superfamily, # 5-induced protein |
3 | BU397996 | 4.53 | 2.82 | 2.18 | 2.74 | 2.20 | 2.87 | Protein Kinase |
Ageing | ||||||||
4 | CR353144 | 4.03 | 1.66 | 3.57 | 3.12 | 2.92 | 3.18 | Nuclear DNA-binding protein |
5 | BU426315 | 4.50 | 2.20 | 2.42 | 2.14 | 1.70 | 1.33 | Carnitine palmitoyltransferase 1A (liver) |
6 | CR523285 | 4.60 | 2.35 | 3.26 | 1.90 | 3.68 | 8.02 | Finshed cDNA clone ChEST613j16 |
7 | CD735693 | 6.05 | 4.25 | 5.44 | 4.66 | 3.68 | 3.39 | Heat shock protein 25 |
8 | BU123548 | 6.47 | 6.16 | 7.31 | 6.30 | 6.14 | 4.20 | Finshed cDNA clone ChEST495e19 |
9 | NM_205471 | 8.73 | 6.99 | 8.76 | 7.69 | 7.42 | 6.28 | Phosphoenolpyruvate carboxykinase 1 |
10 | CR523582 | 6.79 | 5.31 | 4.78 | 5.19 | 4.66 | 4.84 | B-cell CLL/lymphoma 9 |
Cardiovascular | ||||||||
11 | M64990 | 3.94 | 1.69 | 1.51 | 2.10 | 1.02 | 1.25 | Prostaglandin-endoperoxide synthase 2 |
12 | CR522967 | 4.42 | 3.41 | 2.18 | 3.20 | 2.53 | 3.67 | KIAA1285 protein |
13 | ENSGAL T24 | 5.31 | 3.93 | 5.00 | 4.42 | 4.60 | 3.05 | Aproteindipose differentiation-related |
14 | BX935098 | 5.79 | 4.45 | 5.41 | 4.35 | 4.52 | 3.09 | Glutathione S-transferase theta 1 |
15 | BU422942 | 5.84 | 4.14 | 3.65 | 4.09 | 3.79 | 4.41 | Glycogen synthase kinase 3 beta |
16 | BU272340 | 6.58 | 5.63 | 4.23 | 5.47 | 5.39 | 5.81 | Inositol hexaphosphate kinase 2 |
Cancer | ||||||||
17 | AJ447153 | 2.19 | 0.83 | 2.06 | 1.56 | 1.21 | 0.01 | Protein tyrosine phosphate, non-receptor type 2 |
18 | BU463093 | 3.63 | 2.67 | 4.07 | 2.78 | 3.28 | 0.90 | Amino acid transporter system A1 |
19 | AL585963 | 3.95 | 2.15 | 1.74 | 1.20 | 2.07 | 1.67 | RAS guanyl releasing protein 3 |
20 | ENSGAL T0 | 4.24 | 3.18 | 1.62 | 2.42 | 1.85 | 2.97 | Breast cancer-associated antigen BRCAA 1 |
21 | BU131710 | 4.47 | 4.36 | 5.24 | 5.28 | 4.35 | 2.31 | Isopentenyl-diphosphate delta isomerase 1 |
22 | BU111042 | 6.54 | 5.46 | 4.39 | 4.81 | 4.98 | 5.95 | Chrosome 6 open reading frame 111; SR rich protein |
23 | BU458470 | 7.84 | 5.78 | 7.08 | 6.96 | 5.90 | 5.90 | Jun oncogene |