Table 6 Microarray analyses of RNA of livers of chickens after treatment with various compounds.
Genes up-regulated by the first four lipid-lowering compounds, | ||||||||
|---|---|---|---|---|---|---|---|---|
and down-regulated by dexamethasone | ||||||||
# | Genes | Control | δ-T3 | Quer | Ribo | Co lac | Dexa | Description |
1 | CR353609 | 4.47 | 7.23 | 7.13 | 6.67 | 7.12 | 3.95 | Finished cDNA, clone CHEST110e20 |
2 | AJ720605 | 3.07 | 5.39 | 5.65 | 5.23 | 5.04 | 2.66 | Ornithine aminotransferase |
3 | BX265212 | 2.81 | 4.72 | 5.12 | 4.54 | 5.14 | 2.38 | Similar to L-Kynurenine hydrrlase |
4 | CR405837 | 2.76 | 4.89 | 5.27 | 4.49 | 4.95 | 1.89 | Finished cDNA, clone CHEST884a21 |
5 | BU250153 | 3.57 | 5.25 | 5.97 | 5.13 | 5.77 | 3.27 | Selenoprotein P, plasma, 1 |
6 | AJ720030 | 3.29 | 5.00 | 5.62 | 5.35 | 5.13 | 1.62 | Squalene epoxidase |
7 | ENSGALT10 | 2.97 | 4.76 | 5.19 | 4.00 | 4.83 | 3.86 | Assembly = WASHUC1ǀchr = 20ǀstrand = forwardǀcdna |
8 | L07842 | 2.48 | 3.90 | 4.80 | 3.18 | 5.70 | 1.48 | Antithrombin III |
Genes | Genes down-regulated by the first four lipid-lowering compounds, | |||||||
and up-regulated by dexamethasone | ||||||||
1 | CR389189 | 4.60 | 2.35 | 3.26 | 1.90 | 3.68 | 8.02 | Finshed cDNA, clone CHEST613j 16 |
2 | NM204114 | 3.82 | 0.66 | 2.35 | 1.33 | 2.22 | 5.97 | Deiodenase, iodothyronine, type II |
3 | NM_205155 | 4.73 | 5.52 | 6.87 | 5.48 | 5.79 | 9.09 | Fatty acid synthase |
Genes | Genes up-regulated only by dexamethasone | |||||||
1 | BU359098 | 0.84 | 1.08 | 1.04 | 1.25 | 0.88 | 3.69 | BUB 1 uninhibited by benzimidazoles 1 homolog |
Genes | Genes down-regulated only by dexamethasone | |||||||
1 | BU384885 | 2.11 | 3.48 | 4.56 | 2.90 | 3.43 | 1.23 | Hypothetical LOC771662 |