The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Aung, Lynn Htet Htet; Yin, Rui-Xing; Miao, Lin; Hu, Xi-Jiang; Yan, Ting-Ting; Cao, Xiao-Li; Wu, Dong-Feng; Li, Qing; Pan, Shang-Ling; Wu, Jin-Zhen

doi:10.1186/1476-511X-10-5

Lipids in Health and Disease

Table 5 Correlative factors for serum lipid parameters between males and females in both ethnic groups

From: The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Lipid parameter	Relative factor	Unstandardized coefficient	Std. error	Standardized coefficient	t	P
Bai Ku Yao
Male
TC	Body mass index	0.130	0.027	0.267	4.869	0.000
	Age	0.105	0.041	0.139	2.539	0.012
TG	Body mass index	0.128	0.036	0.197	3.516	0.001
HDL-C	Age	0.064	0.018	0.204	3.563	0.000
	Body mass index	-0.031	0.011	-0.155	-2.870	0.004
	Alcohol comsumption	0.117	0.027	0.249	4.325	0.000
LDL-C	Body mass index	0.111	0.022	0.276	5.022	0.000
ApoAI	Age	0.047	0.014	0.185	3.281	0.001
	Alcohol comsumption	0.117	0.022	0.304	5.405	0.000
ApoB	Body mass index	0.032	0.006	0.312	5.741	0.000
ApoAI/ApoB	Body mass index	-0.090	0.023	-0.219	-3.947	0.000
	Pulse pressure	0.009	0.004	0.113	2.044	0.042
	Alcohol comsumption	0.223	0.054	0.230	4.107	0.000
Female
TC	Body mass index	0.040	0.018	0.124	2.282	0.023
	Systolic blood pressure	0.009	0.003	0.187	3.435	0.001
TG	Alcohol comsumption	0.297	0.070	0.231	4.261	0.000
HDL-C	Age	0.045	0.013	0.183	3.340	0.001
LDL-C	Body mass index	0.032	0.014	0.126	2.327	0.021
	Age	0.050	0.025	0.119	2.034	0.043
	Systolic blood pressure	0.006	0.002	0.161	2.731	0.007
ApoAI	Age	0.038	0.009	0.217	3.988	0.000
ApoB	Body mass index	0.010	0.004	0.127	2.338	0.020
	Systolic blood pressure	0.002	0.001	0.202	3.716	0.000
Han Chinese
Male
TC	Diastolic blood pressure	0.030	0.005	0.319	5.736	0.000
	Body mass index	0.046	0.014	0.174	3.259	0.001
	Age	0.093	0.031	0.156	2.996	0.003
TG	Body mass index	0.103	0.020	0.293	5.223	0.000
	Diastolic blood pressure	0.016	0.007	0.127	2.230	0.026
	Alcohol comsumption	0.192	0.087	0.116	2.199	0.029
HDL-C	Age	0.046	0.014	0.187	3.198	0.002
	Body mass index	-0.032	0.006	-0.295	-5.471	0.000
	Alcohol comsumption	0.105	0.027	0.202	3.882	0.000
	Systolic blood pressure	0.005	0.002	0.176	2.947	0.003
	Genotype	0.192	0.084	0.117	2.277	0.023
LDL-C	Diastolic blood pressure	0.017	0.004	0.247	4.351	0.000
	Body mass index	0.039	0.011	0.195	3.440	0.001
ApoAI	Age	0.046	0.009	0.288	5.179	0.000
	Alcohol comsumption	0.075	0.017	0.220	4.448	0.000
	Systolic blood pressure	0.004	0.001	0.209	3.682	0.000
	Body mass index	-0.011	0.004	-0.156	-3.030	0.003
	Genotype	0.128	0.052	0.120	2.444	0.015
ApoB	Diastolic blood pressure	0.006	0.001	0.279	5.154	0.000
	Body mass index	0.017	0.003	0.278	5.141	0.000
ApoAI/ApoB	Body mass index	-0.047	0.009	-0.289	-5.378	0.000
	Pulse pressure	0.009	0.003	0.157	2.813	0.005
	Age	0.056	0.021	0.153	2.700	0.007
Female
TC	Diastolic blood pressure	0.025	0.006	0.234	4.267	0.000
	Body mass index	0.056	0.019	0.168	3.018	0.003
	Age	0.115	0.032	0.195	3.623	0.000
TG	Diastolic blood pressure	0.024	0.006	0.225	4.158	0.000
HDL-C	Age	0.071	0.015	0.263	4.906	0.000
LDL-C	Diastolic blood pressure	0.015	0.005	0.178	3.263	0.001
	Body mass index	0.062	0.014	0.239	4.310	0.000
	Age	0.085	0.025	0.185	3.443	0.001
ApoAI	Age	0.067	0.009	0.373	7.253	0.000
	Alcohol comsumption	0.106	0.052	0.105	2.042	0.042
ApoB	Diastolic blood pressure	0.004	0.001	0.200	3.755	0.000
	Body mass index	0.016	0.004	0.223	4.130	0.000
	Age	0.027	0.007	0.219	4.160	0.000
	Genotype	-0.075	0.037	-0.099	-2.036	0.043
ApoAI/ApoB	Body mass index	-0.032	0.010	-0.181	-3.348	0.001
	Genotype	0.249	0.101	0.133	2.457	0.015

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B.

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ISSN: 1476-511X

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