Figure 2
From: A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells
Effects of WS070117 on hepatic lipids accumulation in HFD fed hamsters. A: Representative frozen tissue sections of liver taken from hamsters fed chow diet, HDF diet, HFD+ simvastatin (2 mg/kg) and HFD+WS070117 (18 mg/kg) were stained with Oil Red-O to demonstrate the reduction in lipid droplets. B: Hepatic TC and TAG were measured in liver samples of control (n = 5), HFD, 8-weeks WS070117 (2, 6, 18 mg/kg) or simvastatin (positive control; 2 mg/kg) treated HFD fed hamsters (n = 8). **P < 0.01, *P < 0.05 as compared with HFD model. ##P < 0.01 as compared with control.