The relation of high fat diet, metabolic disturbances and brain oxidative dysfunction: modulation by hydroxy citric acid

Table 3 Correlation coeffecient between parameters in different groups of rats.

	BChE	TG	TC	Glucose	Abdomin Fat	Final BW	Brain Catalase	Brain NO
BChE	----	P < 0.033 r = 0.96	P < 0.001 r = 0.99	NS	P < 0.007 r = 0. 99	NS	NS	P < 0.04 r = -0. 96
TG	-----	____	P < 0.048 r = 0.95	P < 0.02 r = 0.97	P < 0.021 r = 0.98	-------	P < 0.04 r = 0.90	P < 0.004 r = -0.99
Brain MDA	NS	P < 0.05 r = 0.95	NS	P < 0.007 r = 0.99	NS	P < 0.03 r = 0.91	P < 0.005 r = 0.97	P < 0.05 r = -0.95
Brain Catalase	NS	-----	NS	P < 0.006 r = 0.99	NS	P < 0.03 r = 0.91	____	P < 0.04 r = -0.95
Brain NO	------	------	P < 0.05 r = -0.94	P < 0.024 r = -0.97	P < 0.02 r = -0.98	NS	P < 0.05 r = -0.94	____
Final BW	NS	P < 0.008 r = 0.99	NS	P < 0.013 r = 0.98	P < 0.035 r = 0.96	-----	P < 0.03 r = 0.97	P < 0.002 r = -0. 99

r = Value of correlation coefficient. P ≤ 0.05 indicate significant variation.
Significant positive correlation was detected between BChE activity and serum TG level (P < 0.03 and r = 0.96), TC (P < 0.001 and r = 0.99) and abdominal fat weight (P < 0.007 and r = 0.99), while serum BChE activity had a negative correlation with Brain NO concentration (P < 0.04 and r = -0.96) (Table 3).
Brain MDA positively correlated with TG (P < 0.05 and r = 0.95), blood glucose (P < 0.007 and r = 0.99) and final BW (P < 0.03 and r = 0.91) while, negatively correlated with NO (P < 0.05 and r = -0.95). There were negative correlation between blood glucose and brain NO (P < 0.024 and r = -0.9) (Table 3) in rats group. Also the data showed negative correlation between brain NO and MDA levels (P = 0.05 and r = -0.95), (Table 3).

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