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Table 2 Effect of Simvastatin on plasma lipoprotein lipids and apoA-I concentrations in apoE-/- mice

From: Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet

 

Model (apoE-/-)

Simvastatin (5 mg/kg)

Animal number (n)

11

10

TC(mmol/L)

24.69 ± 5.34

22.07 ± 4.12

TG(mmol/L)

1.13 ± 0.37

1.24 ± 0.47

Non-HDL-C (mmol/L)

22.06 ± 4.87

18.93 ± 3.89

HDL-C (mmol/L)

2.63 ± 0.35

3.14 ± 0.34**

apo-AI(mg/dl)

4.24 ± 1.01

11.58 ± 2.03**

  1. Values are the means ± SD. *compared with model, p < 0.05. **compared with model, p < 0.01
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Lipids in Health and Disease

ISSN: 1476-511X