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Table 2 Effect of Simvastatin on plasma lipoprotein lipids and apoA-I concentrations in apoE-/- mice

From: Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet

  Model (apoE-/-) Simvastatin (5 mg/kg)
Animal number (n) 11 10
TC(mmol/L) 24.69 ± 5.34 22.07 ± 4.12
TG(mmol/L) 1.13 ± 0.37 1.24 ± 0.47
Non-HDL-C (mmol/L) 22.06 ± 4.87 18.93 ± 3.89
HDL-C (mmol/L) 2.63 ± 0.35 3.14 ± 0.34**
apo-AI(mg/dl) 4.24 ± 1.01 11.58 ± 2.03**
  1. Values are the means ± SD. *compared with model, p < 0.05. **compared with model, p < 0.01