Differences and similarities of postprandial lipemia in rodents and humans

Table 1 Postprandial Triglycerides Responses in Wistar Rats, C57/Bl6 Mice, Men and Women

Groups/Postprandial data	Percentage of baseline (0 h) variation								Areas Under curves (mg/dLh)		Acquisition/removal rates (mg/d/h)
	1 h	2 h	3 h	4 h	5 h	6 h	8 h	10 h	AUC TG	AUIC TG	AR TG	RR TG
Wistar Male (31)	-	86 ^a	-	70 ^a	-	158 ^a	127 ^a	125 ^a	1269 ± 105 ^g	539 ± 97 ^h	18 ± 3	21 ± 3 ^l
Wistar Female (12)	-	35 ^b	-	19 ^b	-	17 ^b	11	15	2085 ± 102 ^g	257 ± 91 ^h	30 ± 8	201 ± 21 ^l
CL57BL/6 Male (10)	59 ^c	96 ^c	118 ^c	105	54	76	-	-	619 ± 84 ⁱ	249 ± 92	68 ± 10	50 ± 14
CL57BL/6 Female (9)	91 ^d	108 ^d	51	30	31	38	-	-	839 ± 54 ⁱ	107 ± 88	86 ± 15	46 ± 6
Men (31)	-	79 ^e	-	87 ^e	-	66 ^e	32 ^e	-	1051 ± 74 ^j	402 ± 46 ^k	24 ± 3	19 ± 3
Women (29)	-	57 ^f	-	78 ^f	-	44 ^f	26 ^f	-	734 ± 46 ^j	238 ± 29 ^k	16 ± 2	12 ± 2

Data as means ± SEM; Groups (n); Diet chow intake: 15 g/day; water intake: 30 mL/day. weight of rats: 190 ± 6 g and mice: 24 ± 0.7 g; Percentage of baseline (0 h) variation, areas under curves (AUC) and incremental areas under curves (AUIC); Wilcoxon test: a, b, c and d: differences from 0 h. a < 0.000; b < 0.03, c < 0.008, d < 0.02, e < 0.001, f < 0.003. Mann-Whitney test; g < 0.0001, h < 0.04, i < 0.003, j < 0.002, k < 0.004, l < 0.0001.

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