Table 1 Effects of hydroalcoholic extract of A. caudatus on Selective biochemical parameters in rabbits fed with high cholesterol diets on 0, 45th and 75th days
Biochemical parameters | Duration (days) | GroupI | GroupΙΙ | GroupIII | GroupIV | GroupV |
|---|---|---|---|---|---|---|
0 | 41.4 ± 8.443933 | 47.6 ± 7.436397 | 46.8 ± 7.463243 | 45.4 ± 8.792042 | 45.8 ± 6.723095 | |
45 | 46.8 ± 7.463243 | 898.2 ± 84.3872 | 664 ± 192.3382 | 786.2 ± 180.7836 | 876.8 ± 100.3927 | |
Cholesterol(m g/dl) | 75 | 47.6 ± 7.436397 | ------------- | 1053.2 ± 34.76636 | 1020.8 ± 72.58237 | 575 ± 34.12477ba |
0 | 45.267 ± 11.58879 | 55.8 ± 6.797058 | 58.2 ± 7.823043 | 44.2 ± 12.39758 | 59 ± 10.65364 | |
45 | 45.267 ± 12.39758 | 166.2 ± 30.32656 | 109.4 ± 20.59854 | 156.2 ± 36.46505 | 131.6 ± 7.700649 | |
Triglyceride (mg/dl) | 75 | 46.233 ± 1.16301 | ------------- | 238.4 ± 55.13892 | 195.8 ± 54.29273 | 85.6 ± 7.700649 |
0 | 16.42 ± 1.99925 | 17.42 ± 1.485598 | 15.086 ± 1.117578 | 16.96 ± 1.7358 | 16.98 ± 1.01341 | |
45 | 17.1 ± 1.604681 | 837.2 ± 65.78146 | 839.2 ± 46.21904 | 813.2 ± 73.41117 | 660.62 ± 361.4526 | |
LDL-cholesterol mg/dl) | 75 | 17.38 ± 1.070981 | -------------- | 952.98 ± 50.06078 | 694.88 ± 45.25231b | 426.8 ± 36.0236b |
0 | 23.4 ± 9.607289 | 16.8 ± 3.114482 | 18.6 ± 2.607681 | 17.4 ± 3.130495 | 19.4 ± 6.107373 | |
45 | 20.8 ± 5.630275 | 61.6 ± 12.05404 | 56.8 ± 10.56882 | 82 ± 14.91643 | 70.8 ± 10.84896 | |
HDL- cholesterol (mg/dl) | 75 | 19 ± 5.43139 | -------------- | 81.2 ± 16.42255 | 86.4 ± 17.85497 | 134.2 ± 11.14451ba |
0 | 8.2 ± 1.48324 | 10.2 ± 4.91935 | 13.6 ± 4.037326 | 14.2 ± 3.563706 | 14.4 ± 3.781534 | |
45 | 14 ± 4.52769 | 34.8 ± 10.32957 | 30 ± 9.082951 | 27 ± 5.522681 | 28.8 ± 4.658326 | |
apolipoprotein B (mg/dl) | 75 | 9.8667 ± 1.30384 | ------------- | 58.2 ± 11.43241 | 49.2 ± 11.64903 | 41 ± 8.602325 |
0 | 43 ± 9.823441 | 42.2 ± 9.364828 | 43.6 ± 11.90798 | 41.8 ± 8.757854 | 41.4 ± 12.83745 | |
45 | 47.8 ± 5.215362 | 27.2 ± 7.362065 | 27.6 ± 7.924645 | 28.8 ± 6.648308 | 29.6 ± 6.308724 | |
apolipoprotein A (mg/dl) | 75 | 34.8 ± 8.288546 | -------------- | 22.4 ± 7.765307 | 21 ± 9.66954 | 52.4 ± 8.961027ba |
0 | 0.3 ± 0.141421 | 0.16 ± 0.089443 | 0.2 ± 0.141421 | 0.2 ± 0.141421 | 0.2 ± 0.1 | |
45 | 0.2 ± 1.604681 | 0.7 ± 0.070711 | 0.68 ± 0.164317 | 0.64 ± 0.151658 | 0.7 ± 0.070711 | |
de Malondialdehy (mol/l) | 75 | 0.22 ± 0.130384 | -------------- | 1.7 ± 0.234521 | 0.92 ± 0.204939b | 0.35 ± 0.070711ba |
0 | 3.02 ± 0.141421 | 3.66 ± 1.934683 | 2.26 ± 1.062073 | 2.66 ± 1.825651 | 2.32 ± 1.634625 | |
C-reactive protein (mg/l) | 45 | 2.96 ± 1.564609 | 12.82 ± 3.094673 | 11.36 ± 3.706481 | 14.08 ± 2.259867 | 12.46 ± 3.304996 |
75 | 2.58 ± 1.88202 | -------------- | 23.4 ± 3.361547 | 8.9 ± 0.514782b | 5.1 ± 1.031988ba | |
0 | 15.12 ± 1.41492 | 15.26 ± 1.209545 | 15.22 ± 1.243785 | 15.72 ± 2.667771 | 14.46 ± 1.209545 | |
45 | 16.22 ± 2.615722 | 23.32 ± 2.963444 | 23.32 ± 3.013636 | 25.72 ± 4.130617 | 26.12 ± 3.62519 | |
OX- LDL(ng/ml) | 75 | 15.5 ± 2.382226 | -------------- | 35.12 ± 5.157713 | 25.54 ± 3.72599 | 18.82 ± 1.411382b |
0 | 42.358 ± 8.124376 | 46.554 ± 7.265138 | 45.284 ± 8.458223 | 45.862 ± 12.62378 | 44.846 ± 6.728988 | |
45 | 45.926 ± 7.531051 | 884.204 ± 83.63083 | 729.088 ± 148.0296 | 738.548 ± 148.253 | 867.5016 ± 102.6377 | |
AI | 75 | 46.642 ± 7.538247 | -------------- | 1040.96 ± 33.85897 | 1011.03 ± 26.33166 | 551.062 ± 71.06503b |