Figure 1

Carriers of APOC3 variant alleles (-482T, -455C or both) were compared with homozygous for the wild-type alleles at both SNPs (-482C and -455T alleles) for glucose and insulin measurements during oral glucose tolerance test (OGTT). The study cohort underwent OGTT (75 g) test and glucose and insulin were measured baseline (0) and at 30, 60, 90 and 120 min after the administration of glucose. (A) Median glucose and (B) insulin in individuals stratified by the genotypes. No statistical differences were found in either insulin or glucose at different time points in the two groups. P-values were calculated by linear regression (all P-values = NS), including age, gender and body mass index (BMI) as covariates in the model.