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Figure 3 | Lipids in Health and Disease

Figure 3

From: SR-BI associates with ABCG1 and inhibits ABCG1-mediated cholesterol efflux from cells to high-density lipoprotein 3

Figure 3

SR-BI inhibits ABCG1-mediated cellular cholesterol efflux. CHO cells were transiently transfected with SR-BI alone, ABCG1 alone, and SR-BI plus ABCG1 (co-transfection). 24 h after transfection, cholesterol efflux was initiated by the addition of HDL3 (150 μg protein/ml) to medium for 24 h. The increased FC (A), CE (B) and TC (C) mass in medium were determined. Values are means ± SD of three independent experiments. * p < 0.05, ** p < 0.01. D shows the western blots of SR-BI and ABCG1 protein in vector transfected, SR-BI transfected, ABCG1 transfected and cotransfected cells.

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Lipids in Health and Disease

ISSN: 1476-511X