|
Groups
|
Body weight gain (g)
|
Body-liver weight (g)
|
Food intake (g/mouse/day)
|
Drug intake (g/kg/day)
|
|---|
|
Normal diet for 13 days
|
|
Normal diet
|
8.55 ± 0.11
|
24.64 ± 0.36
|
4.20
| |
|
1% AqFSC/normal diet
|
8.11 ± 0.19
|
24.63 ± 0.63
|
4.55
|
1.45
|
|
4% AqFSC/normal diet
|
8.05 ± 0.34
|
24.15 ± 0.58
|
4.32
|
5.56
|
|
1% EtFSC/normal diet
|
8.31 ± 0.15
|
24.53 ± 0.43
|
4.43
|
1.35
|
|
4% EtFSC/normal diet
|
8.45 ± 0.25
|
24.38 ± 0.43
|
4.21
|
5.43
|
|
0.1% Fenofibrate/normal diet
|
5.09 ± 0.08*
|
20.40 ± 0.28*
|
4.53
|
0.18
|
|
HFCB diet for 13 days
|
|
Normal diet
|
8.00 ± 0.43
|
25.72 ± 0.63
|
4.31
|
-
|
|
HFCB diet
|
7.52 ± 0.25
|
24.96 ± 0.54
|
3.85
|
-
|
|
1% AqFSC/HFCB diet
|
8.23 ± 0.67
|
24.76 ± 0.59
|
4.56
|
1.59
|
|
4% AqFSC/HFCB diet
|
7.96 ± 0.42
|
25.49 ± 0.63
|
4.89
|
6.68
|
|
1% EtFSC/HFCB diet
|
8.80 ± 0.35
|
25.29 ± 0.76
|
5.50
|
1.99
|
|
4% EtFSC/HFCB diet
|
8.71 ± 0.52
|
25.25 ± 0.72
|
4.23
|
6.13
|
|
0.1% Fenofibrate/HFCB diet
|
7.33 ± 0.32
|
22.51 ± 0.72†
|
4.31
|
0.17
|
- Experimental details were described in Table1. The dosages (g/kg/day) based on crude herbal material were determined with respect to the amount of ingested diet (g/day/kg) and drug concentrations in the diet. Values given are the mean ± S.E.M., with n = 10. *Significantly different from the normal diet group (p < 0.01); †significantly different from the hypercholesterolemic mice (p < 0.01).
