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Table 2 Effects of dietary supplementation of AqFSC, EtFSC, or fenofibrate on body weight gain and food/drug intake in the normal and hypercholesterolemic mice

From: Dietary Fructus Schisandrae extracts and fenofibrate regulate the serum/hepatic lipid-profile in normal and hypercholesterolemic mice, with attention to hepatotoxicity

Groups Body weight gain (g) Body-liver weight (g) Food intake (g/mouse/day) Drug intake (g/kg/day)
Normal diet for 13 days
Normal diet 8.55 ± 0.11 24.64 ± 0.36 4.20  
1% AqFSC/normal diet 8.11 ± 0.19 24.63 ± 0.63 4.55 1.45
4% AqFSC/normal diet 8.05 ± 0.34 24.15 ± 0.58 4.32 5.56
1% EtFSC/normal diet 8.31 ± 0.15 24.53 ± 0.43 4.43 1.35
4% EtFSC/normal diet 8.45 ± 0.25 24.38 ± 0.43 4.21 5.43
0.1% Fenofibrate/normal diet 5.09 ± 0.08* 20.40 ± 0.28* 4.53 0.18
HFCB diet for 13 days
Normal diet 8.00 ± 0.43 25.72 ± 0.63 4.31 -
HFCB diet 7.52 ± 0.25 24.96 ± 0.54 3.85 -
1% AqFSC/HFCB diet 8.23 ± 0.67 24.76 ± 0.59 4.56 1.59
4% AqFSC/HFCB diet 7.96 ± 0.42 25.49 ± 0.63 4.89 6.68
1% EtFSC/HFCB diet 8.80 ± 0.35 25.29 ± 0.76 5.50 1.99
4% EtFSC/HFCB diet 8.71 ± 0.52 25.25 ± 0.72 4.23 6.13
0.1% Fenofibrate/HFCB diet 7.33 ± 0.32 22.51 ± 0.72 4.31 0.17
  1. Experimental details were described in Table1. The dosages (g/kg/day) based on crude herbal material were determined with respect to the amount of ingested diet (g/day/kg) and drug concentrations in the diet. Values given are the mean ± S.E.M., with n = 10. *Significantly different from the normal diet group (p < 0.01); significantly different from the hypercholesterolemic mice (p < 0.01).