Table 7 Within sib pair association statistics for seven SNPs with lead lipid traits after stratifying for fat intake
From: Evaluation of seven common lipid associated loci in a large Indian sib pair study
Gene | Trait tested | Low fat intake | Medium fat intake | Interaction effect |
|---|---|---|---|---|
APOA5 | Triglycerides | 0.18 (0.08, 0.29, p=3.4 x 10-4) | 0.19 (0.08, 0.29, p=0.001) | 0.04 (−0.10, 0.19, p=0.55) |
APOB | LDL-Cholesterol | −0.11 (−0.23, 0.02, p=0.09) | −0.07 (−0.18, 0.04, p=0.21) | 0.06 (−0.12, 0.23, p=0.53) |
CETP | HDL-Cholesterol | 0.01 (−0.08, 0.11, p=0.78) | −0.03 (−0.13, 0.07, p=0.61) | −0.03 (−0.18, 0.11, p=0.63) |
GCKR | Triglycerides | 0.11 (0.02, 0.21, p=0.02) | 0.13 (0.03, 0.23, p=0.01) | −0.03 (−0.17, 0.11, p=0.69) |
LDLR | LDL-Cholesterol | 0.02 (−0.15, 0.20, p=0.77) | −0.20 (−0.36, -0.04, p=0.02) | −0.03 (−0.18, 0.11, p=0.63) |
LIPC | HDL-Cholesterol | 0.09 (−0.004, 0.18, p=0.06) | 0.09 (−0.004, 0.19, p=0.06) | 0.05 (−0.09, 0.19, p=0.48) |
LPL | Triglycerides | −0.14 (−0.27, -0.004, p=0.04) | −0.21 (−0.34, -0.07, p=0.002) | −0.01 (−0.20, 0.17, p=0.87) |