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Table 4 Odds ratios and 95% confidence intervals for predicting CAD in various lipidemic groups and in all subjects

From: Identification of the HDL-ApoCIII to VLDL-ApoCIII ratio as a predictor of coronary artery disease in the general population: The Chin-Shan Community Cardiovascular Cohort (CCCC) study in Taiwan

 

Odds Ratio

95%CI

P value

NL Group a

   

HDL-ApoCIII

1.49

1.12–1.99

0.006

VLDL-ApoCIII

0.74

0.53–1.01

0.06

HDL-ApoCIII/ VLDL-ApoCIII

1.85

1.14–2.89

0.01

Men

2.76

1.57–3.48

0.005

Women

1.65

1.06–2.33

0.02

ApoAI

0.62

0.46–0.84

0.002

HTG Group a

   

HDL-ApoCIII

2.00

1.05–3.80

0.04

VLDL-ApoCIII

0.79

0.45–1.41

0.43

HDL-ApoCIII/ VLDL-ApoCIII

2.52

0.76–5.98

0.02

Men

3.17

1.14–3.94

0.005

Women

1.55

1.04–1.89

0.03

HC Group a

   

HDL-ApoCIII

1.56

1.18–2.05

0.002

VLDL-ApoCIII

0.74

0.61–0.90

0.003

HDL-ApoCIII/ VLDL-ApoCIII

1.78

1.23–2.67

0.003

Men

1.96

1.26–2.67

0.005

Women

1.23

1.06–1.89

0.01

ApoAI

0.72

0.55–0.93

0.01

HLP Group a

   

HDL-ApoCIII

0.90

0.64–1.28

0.57

VLDL-ApoCIII

0.66

0.54–0.81

<0.0001

HDL-ApoCIII/ VLDL-ApoCIII

1.57

1.01–2.24

0.01

Men

1.80

1.26–2.72

0.004

Women

1.25

0.94–1.88

0.02

TG

0.96

0.94–0.99

0.005

TC

1.16

1.04–1.30

0.006

LDL-C

0.83

0.73–0.94

0.004

ApoAI

0.21

0.07–0.68

0.009

All Subjects, Final Modelb

   

HDL-ApoCIII/ VLDL-ApoCIII

2.04

1.46–2.84

<0.0001

Female sex

0.26

0.10–0.66

0.0043

Age

1.06

1.02–1.10

0.0063

TC

1.04

1.01–1.06

0.002

TG

0.99

0.99–1.00

<0.0001

LDL-C

0.99

0.98–1.00

0.01

HDL-C

0.95

0.90–1.00

0.03

ApoB

1.46

1.25–1.70

<0.0001

ApoAI

0.66

0.55–0.80

<0.0001

  1. CAD = coronary artery disease; CI = confidence interval; NL = normolipidemic; HDL = high-density lipoprotein; VLDL = very-low-density lipoprotein; Apo = apolipoprotein; HTG = hypertriglyceridemic; HC = hypercholesterolemic; HLP = hyperlipidemic; TG = triglyceride; TC = total cholesterol; LDL-C = low-density lipoprotein cholesterol.
  2. aThe following co-variables were entered in the multivariate regression model: TG, TC, ApoAI, ApoB, ApoCIII, ApoE, LDL-C, HDL-C, HDL-ApoE, VLDL-ApoE, and forced entry of HDL-ApoCIII and VLDL-ApoCIII.
  3. bThe following co-variables were entered in the multivariate regression model: TG, TC, ApoAI, ApoB, Lp(a), ApoCIII, ApoE, LDL-C, HDL-C, HDL-ApoE, VLDL-ApoE and HDL-ApoCIII/VLDL-ApoCIII ratio.
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Lipids in Health and Disease

ISSN: 1476-511X