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Table 1 Comparison of general characteristics and serum lipids between AD patients and controls

From: Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer’s disease

Variable Cases Controls t-value or χ2 P
N 104 104   
Age(years) 77.8±6.74 76.5±6.14 −1.495 0.137
Male/female 57/47 56/48 0.019 0.889
Systolic blood pressure(mmHg) 138.1±19.5 134.7±19.5 −1.239 0.217
Diastolic blood pressure(mmHg) 79.6±9.56 76.6±9.65 −2.256 0.025
Cigarette smoking[n(%)] 27(26.0) 40(38.8) 3.918 0.048
Alcohol consumption[n(%)] 8(7.7) 6(5.8) 0.286 0.593
History of hypertension[n(%)] 58(56.3) 64(64.6) 1.466 0.226
History of hyperlipidemia[n(%)] 44(42.3) 27(26.0) 6.180 0.013
History of diabetes[n(%)] 26(25.0) 15(15.2) 3.052 0.081
History of CHD[n(%)] 46(44.7) 41(41.4) 0.217 0.641
Education(proportion of high school and above level) 17(16.3) 36(34.6) 9.140 0.003
TG(mmol/L) 1.36±0.62 1.32±0.71 −0.909 0.364
TC(mmol/L) 4.48±0.89 4.10±1.04 −2.826 0.005
HDL-C(mmol/L) 1.33±0.31 1.44±0.31 2.450 0.015
LDL-C(mmol/L) 2.46±0.66 2.40±0.82 −0.848 0.397
ApoA-I(g/L) 1.17±0.28 1.21±0.22 1.162 0.247
ApoB(g/L) 0.79±0.22 0.80±0.22 0.089 0.929
  1. TC, Total cholesterol; TG, Triglycerides; HDL-C, highdensity lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Apo, Apolipoproteins.