Table 1 Baseline demographics and clinical characteristics
EZ/Simva 10/40 mg n (%) | Atorvastatin 40 mg n (%) | Total | |
|---|---|---|---|
N = 120 | N = 130 | N = 250 | |
Male | 63 (52.5) | 65 (50.0) | 128 (51.2) |
Mean age (SD) | 58.9 (10.0) | 59.7 (8.4) | 59.3 (9.2) |
Age ≥ 65 years | 36 (30.0) | 36 (27.7) | 72 (28.8) |
Race | |||
White | 89 (74.2) | 90 (69.2) | 179 (71.6) |
Asian | 21 (17.5) | 24 (18.5) | 45 (18) |
Multi-Racial | 10 (8.3) | 14 (10.8) | 24 (9.6) |
American Indian or Alaska Native | 0 | 1 (0.8) | 1 (0.4) |
Black or African American | 0 | 1 (0.8) | 1 (0.4) |
Ethnicity--Hispanic or Latino | 25 (20.8) | 29 (22.3) | 54 (21.6) |
Baseline LDL-C Stratum | |||
Stratum 1: ≥ 2.59 mmol/L (100 mg/dL) to < 3.36 mmol/L (130 mg/dL) | 81 (67.5) | 97 (74.6) | 178 (71.2) |
Stratum 2: ≥ 3.36 mmol/L (130 mg/dL) to < 4.14 mmol/L (160 mg/dL) | 39 (32.5) | 33 (25.4) | 72 (28.8) |
BMI ≥ 30 kg/m2 | 43 (37.1) | 41 (32.3) | 84 (34.6) |
History of Diabetes | 42 (35.0) | 45 (34.6) | 87 (34.8) |
Clinical Characteristics, mean (SD) | |||
LDL-C, mmol/L mg/dL | 3.16 (0.43) 122.00 (16.5) | 3.08 (0.40) 119.01 (15.52) | 3.12 (0.42) 120.44 (16.04) |
Total Cholesterol, mmol/L mg/dL | 5.25 (0.55) 202.54 (21.1) | 5.14 (0.60) 198.60 (23.11) | 5.19 (0.59) 200.49 (22.21) |
Triglycerides*, mmol/L mg/dL | 1.53 (0.76) 135.00 (66.98) | 1.49 (0.76) 131.50 (66.98) | 1.49 (0.76) 132.00 (66.98) |
HDL-C, mmol/L mg/dL | 1.33 (0.33) 51.54 (12.87) | 1.33 (0.35) 51.18 (13.28) | 1.33 (0.34) 51.36 (13.06) |
non-HDL-C, mmol/L mg/dL | 3.91 (0.51) 151.00 (19.56) | 3.82 (0.51) 147.42 (19.68) | 3.86 (0.51) 149.14 (19.67) |
Apo B, g/L (mg/dL) | 1.20 (0.16) 119.87 (16.06) | 1.17 (0.16) 117.32 (15.83) | 1.19 (0.16) 118.54 (15.96) |
Apo A-I, g/L (mg/dL) | 1.15 (0.25) 155.15 (24.78) | 1.58 (0.28) 157.69 (28.28) | 1.60 (0.27) 156.47 (26.63) |
LDL-C/HDL-C | 2.50 (0.64) | 2.46 (0.65) | 2.48 (0.64) |
Total C/HDL-C | 4.12 (0.89) | 4.07 (0.91) | 4.09 (0.9) |
non-HDL-C/HDL-C | 3.12 (0.89) | 3.07 (0.91) | 3.09 (0.90) |
Apo B/Apo A-I | 0.80 (0.17) | 0.77 (0.18) | 0.78 (0.18) |
hs-CRP*, mg/L | 2.15 (2.7) | 2.10 (2.7) | 2.10 (2.7) |