Skip to main content

Table 3 Subject fatty acid profiles.

From: Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders

  Group
  Control (n = 6) DD (n = 6) FML (n = 8) MSL (n = 5)
  Saturated and Monounsaturated Fatty Acids Percent of Total (SEM)
14:0 (myristic) 1.22 (1.17-1.38) 1.74 (1.52-1.78)**† 1.30 (1.08-1.47) 1.53 (1.12-2.29)
16:0 (palmitic) 27.4 (24.8-28.5) 27.3 (26.0-29.2) 25.4 (25.2-28.3) 26.3 (23.0-31.6)
16:1n-7 (palmitoleic) 3.68 (2.90-4.04) 2.78 (2.18-3.43) 2.71 (2.27-3.28) 4.04 (3.24-4.95)
18:0 (stearic) 4.15 (3.93-5.52) 6.07 (5.81-7.92) 5.80 (5.59-7.21) 3.88 (2.21-7.72)
18:1X ¥ 1.95 (1.87-2.54) 1.52 (1.12-1.92) 1.91 (1.43-2.01) 1.71 (1.27-2.14)
18:1n-9 (oleic) 47.8 (46.1-48.9) 48.5 (47.5-49.0) 48.2 (46.9-48.7) 46.6 (43.3-51.9)
18:1n-7 (vaccenic) 3.22 (2.72-5.70) 2.01 (1.72-2.61)†‡ 5.85 (4.09-6.25) 2.95 (2.64-6.31)
18:1Y ¥ 0.82 (0.75-0.94) not detected 2.22 (2.05-2.38) 0.82 (N/A)
20:1n-9
(eicosenoic) ¥
0.65 (0.60-0.73) 0.60 (0.52-0.72) 0.70 (0.62-0.79) 0.50 (0.49-0.54)
Total percent SFA 33.4 (29.1-34.8) 36.2 (35.7-38.6) 33.0 (31.1-35.5) 31.3 (26.6-41.7)
Total percent MUFA 57.9 (54.8-59.8) 54.4 (53.5-56.2) 57.0 (55.2-60.2) 56.4 (53.1-61.0)
  Polyunsaturated Fatty Acids Percent of Total (SEM)
18:2n-6
(linoleic, LA)
9.12 (8.31-10.4) 8.34 (8.10-8.89) 9.65 (8.07-9.94) 5.64 (4.61-8.50)
18:3n-3
(α-linolenic, ALA)
0.23 (0.17-0.26) 0.24 (0.18-0.32) 0.21 (0.17-0.26) 0.15 (0.12-0.17)‡†
20:4n-6 (arachidonic, AA) 0.13 (0.10-0.16) 0.10 (0.09-0.13) 0.13 (0.11-0.20) 0.14 (0.13-0.41)#
Total percent PUFA (LA+ALA+AA) 9.49 (8.58-10.8) 8.61 (8.31-9.29) 10.0 (8.35-10.3) 6.21 (5.07-8.80)*
n-6/n-3 ratio (LA+AA)/ALA
(arbitrary units)
43.3 (40.1-50.4) 36.8 (29.2-47.1) 44.6 (37.7-51.4) 40.1(30.5-50.3)
  1. The median percent of total is presented with the 25-75% interquartile range in parentheses. In DD, myristic acid percent of total is increased compared to Controls and FML. Vaccenic acid percent of total trends toward a decrease compared to Controls, but is significantly lower compared to FML
  2. DD Dercum's disease, FML Familial multiple lipomatosis, MSL Multiple symmetric lipomatosis
  3. *p < 0.05 vs. Control; **p < 0.01 vs. Control; †p < 0.05 vs. FML; ‡ trended lower vs. Control (see text);
  4. #trended higher vs.DD; ¥no comparison between groups made due to low prevalence in the groups; N/A non-applicable because not detected in enough subjects to provide a value