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Table 1 Pearson's correlation coefficient (age vs mRNA levels of selected genes)

From: Changes in cholesterol metabolism-related gene expression in peripheral blood mononuclear cells from Alzheimer patients

 

C1 + C2 (n.25)

AD + FDR-AD (n.25)

Neprilysin

r = -0,8992

r = -0,2233

 

p = 0,000

p = 0,283

ABCA-1

r = -0,3503

r = 0,2457

 

p = 0,086

p = 0,236

ACAT-1

r = -0,7171

r = -03421

 

p = 0,000

p = 0,094

APP

r = -0,5171

r = 0,4477

 

p = 0,008

p = 0,025

BACE-1

r = -0,5849

r = -0,3629

 

p = 0,002

p = 0,075

Cav-1

r = -0,6192

r = 0,0718

 

p = 0,001

p = 0,733

HMGCoA-R

r = -0,4843

r = -0,4748

 

p = 0,014

p = 0,016

LDL-R

r = -0,8361

r = -0,6829

 

p = 0,000

p = 0,000

nCEH

r = -0,7544

r = -0,0151

 

p = 0,000

p = 0,943

SREBP-2

r = -0,7633

r = -0,2629

 

p = 0,000

p = 0,204

  1. Significant statistical differences were indicated in bold