Increased LDL susceptibility to oxidation accelerates future carotid artery atherosclerosis

Table 2 Multivariable odds ratios of risk factors at baseline for future increase in IMT

Characteristic^a	Age-adjusted model^b		Multivariate model^c
	OR (95% CI)^d	P	OR (95% CI)	P
Age			1.035 (1.009 - 1.062)	0.009
Sex (male/female) (n)	0.744 (0.491 - 1.129)	0.165	0.732 (0.454 - 1.179)	0.199
LDL cholesterol (mmol/L)	1.005 (0.998 - 1.012)	0.147	1.006 (0.998 - 1.014)	0.144
HDL cholesterol (mmol/L)	1.000 (0.987 - 1.013)	0.998	1.010 (0.994 - 1.026)	0.234
Triglyceride (mmol/L)	1.002 (0.998 - 1.005)	0.371	1.001 (0.997 - 1.005)	0.670
Fasting plasma glucose (mmol/L)	1.012 (0.996 - 1.027)	0.137	1.001 (0.983 - 1.021)	0.877
HbA1c (%)	1.440 (0.960 - 2.160)	0.078	1.421 (0.878 - 2.298)	0.153
Fasting insulin (pmol/L)	1.017 (0.996 - 1.070)	0.531	1.013 (0.958 - 1.071)	0.646
Systolic blood pressure (mmHg)	1.000 (0.989 - 1.011)	0.985	0.995 (0.979 - 1.012)	0.589
Diastolic blood pressure (mmHg)	1.006 (0.985 - 1.027)	0.596	1.009 (0.978 - 1.041)	0.574
Body mass index (kg/m²)	1.035 (0.959 - 1.119)	0.376	1.026 (0.937 - 1.123)	0.584
Photometric O/N	1.919 (0.959 - 3.838)	0.065	1.943 (0.931 - 4.056)	0.077
Electrophoretic O/N	1.031 (0.479 - 2.220)	0.937	0.908 (0.386 - 2.135)	0.825

^aData at 1996-1997. ^bData adjusted for age. ^cVariables in model were age, sex, LDL-cholesterol, HDL-cholesterol, triglyceride, fasting plasma glucose, HbA1c, fasting insulin, systolic blood pressure, diastolic blood pressure, BMI, photometric O/N, and electrophoretic O/N. ^dOR, odds ratio; CI, 95% confidence interval.

ISSN: 1476-511X