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Table 3 Mean Concentrations ± SE of the of Various Oxidative and Inflammatory Molecules

From: Fish oil improves hemodynamic stabilization and inflammation after resuscitation in a rat model of hemorrhagic shock

 

30 Minutes Post-resuscitation

4 Hours Post-resuscitation

 

Sham

HS

HS/R

FO

Sham

HS

HS/R

FO

TNF-α (pg/mL)

59.53 ± 15.02

197.59 ± 18.33*

222.02 ± 13.21*

243.0 ± 10.2*

42.00 ± 1.08

197.59 ± 18.33* #

66.07 ± 9.03

43.31 ± 0.084

IL-6 (pg/mL)

21.71 ± 0.78

84.80 ± 5.66* #

122.01 ± 24.72* #

22.26 ± 2.35

22.80 ± 1.06

84.80 ± 5.66*

122.85 ± 31.23* #

54.89 ± 5.22

Endotoxin(EU/mL)

0.22 ± 0.009

0.87 ± 0.056* #

1.26 ± 0.116* #

0.24 ± 0.016

0.29 ± 0.046

0.87 ± 0.056* #

3.60 ± 0.358* #

2.58 ± 0.24*

Total GSH (μmol/L)

703.75 ± 9.64

741.10 ± 31.76

714.96 ± 23.40

719.47 ± 13.0

680.77 ± 31.9

741.1 ± 31.77

719.47 ± 16.65

717.1 ± 16.89

Reduced-GSH (μmol/L)

273.71 ± 15.4

259.00 ± 5.83

255.91 ± 3.87

262.84 ± 21.2

283.31 ± 8.02

259.00 ± 5.83

254.33 ± 8.14

269.42 ± 3.48

Reduced/total GSH

0.78 ± 0.047

0.70 ± 0.033

0.72 ± 0.013

0.73 ± 0.06

0.81 ± 0.073

0.70 ± 0.033

0.70 ± 0.033

0.75 ± 0.060

MDA (μmol/L)

15.72 ± 11.59

43.91 ± 1.96* #

52.55 ± 5.22* #

27.78 ± 4.54*

12.32 ± 5.16

43.91 ± 1.96* #

59.67 ± 12.87* #

17.55 ± 5.14

MPO(μmol/L)

26.55 ± 3.61

199.11 ± 18.06* #

257.74 ± 12.18* #

172.5 ± 58.3*

27.50 ± 8.08

199.11 ± 18.06* #

356.93 ± 9.21* #

61.95 ± 6.26

  1. * P < 0.01 vs sham group (1-way ANOVA); # P < 0.01 shock and resuscitation group vs FO group