Association of rs5888 SNP in the scavenger receptor class B type 1 gene and serum lipid levels

Wu, Dong-Feng; Yin, Rui-Xing; Hu, Xi-Jiang; Aung, Lynn Htet Htet; Cao, Xiao-Li; Miao, Lin; Li, Qing; Yan, Ting-Ting; Wu, Jin-Zhen; Pan, Shang-Ling

doi:10.1186/1476-511X-11-50

Lipids in Health and Disease

Table 4 Correlative factors for serum lipid parameters between males and females

From: Association of rs5888 SNP in the scavenger receptor class B type 1 gene and serum lipid levels

Lipid parameter	Relative factor	Unstandardized coefficient	Std. error	Standardized coefficient	t	P
Bai Ku Yao/male
TC	Body mass index	0.120	0.028	0.245	4.268	0.000
TG	Body mass index	0.112	0.033	0.200	3.436	0.001
HDL-C	Alcohol consumption	0.192	0.036	0.304	5.274	0.000
	Age	0.006	0.002	0.189	3.302	0.001
	Genotype	−0.416	0.137	−0.166	−3.036	0.003
	Body mass index	−0.026	0.012	−0.116	−2.116	0.035
LDL-C	Body mass index	0.098	0.024	0.236	4.092	0.000
ApoAI	Alcohol consumption	0.170	0.028	0.342	6.048	0.000
	Age	0.004	0.001	0.155	2.743	0.006
	Genotype	−0.287	0.107	−0.145	−2.690	0.008
ApoB	Body mass index	0.029	0.006	0.267	4.677	0.000
ApoAI/ApoB	Alcohol consumption	0.376	0.071	0.301	5.274	0.000
	Body mass index	−0.069	0.025	−0.157	−2.752	0.006
Bai Ku Yao/female
TC	Systolic blood pressure	0.007	0.003	0.145	2.602	0.010
	Body mass index	0.036	0.017	0.120	2.138	0.033
	Genotype	0.165	0.078	0.118	2.118	0.035
TG	Alcohol consumption	0.311	0.079	0.219	3.961	0.000
LDL-C	Genotype	0.151	0.061	0.135	2.465	0.014
	Body mass index	0.034	0.014	0.141	2.519	0.012
	Age	0.005	0.003	0.122	1.997	0.047
ApoAI	Age	0.002	0.001	0.141	2.509	0.013
ApoB	Systolic blood pressure	0.002	0.001	0.175	3.134	0.002
	Body mass index	0.012	0.005	0.143	2.572	0.011
ApoAI/ApoB	Diastolic blood pressure	−0.007	0.003	−0.139	−2.466	0.014
Han/male
TC	Diastolic blood pressure	0.019	0.005	0.227	3.783	0.000
	Age	0.013	0.003	0.239	4.243	0.000
	Alcohol consumption	0.249	0.071	0.186	3.494	0.001
	Body mass index	0.031	0.015	0.120	2.108	0.036
TG	Body mass index	0.119	0.021	0.320	5.729	0.000
	Cigarette smoking	0.282	0.092	0.172	3.069	0.002
	Genotype	0.292	0.132	0.125	2.216	0.027
HDL-C	Alcohol consumption	0.177	0.034	0.287	5.223	0.000
	Age	0.006	0.001	0.237	4.082	0.000
	Body mass index	−0.029	0.007	−0.243	−4.147	0.000
	Diastolic blood pressure	0.006	0.002	0.156	2.523	0.012
	Genotype	−0.082	0.041	−0.108	−2.011	0.045
LDL-C	Age	0.009	0.003	0.210	3.450	0.001
	Diastolic blood pressure	0.009	0.004	0.142	2.181	0.030
	Body mass index	0.026	0.013	0.128	2.082	0.038
ApoAI	Alcohol consumption	0.161	0.023	0.369	6.960	0.000
	Age	0.005	0.001	0.281	5.301	0.000
ApoB	Body mass index	0.015	0.003	0.283	5.122	0.000
	Age	0.003	0.001	0.245	4.418	0.000
	Alcohol consumption	0.035	0.015	0.132	2.384	0.018
ApoAI/ApoB	Body mass index	−0.036	0.008	−0.272	−4.721	0.000
	Alcohol consumption	0.161	0.039	0.240	4.150	0.000
Han/female
TC	Age	0.020	0.004	0.292	5.413	0.000
	Body mass index	0.074	0.017	0.232	4.308	0.000
TG	Body mass index	0.057	0.016	0.196	3.499	0.001
HDL-C	Cigarette smoking	0.479	0.198	0.137	2.425	0.016
LDL-C	Age	0.016	0.003	0.299	5.612	0.000
	Body mass index	0.066	0.014	0.254	4.769	0.000
ApoAI	Age	0.004	0.001	0.209	3.761	0.000
	Cigarette smoking	0.316	0.124	0.142	2.559	0.011
ApoB	Body mass index	0.022	0.003	0.344	6.530	0.000
	Age	0.003	0.001	0.223	4.228	0.000
ApoAI/ApoB	Body mass index	−0.042	0.010	−0.236	−4.335	0.000
	Cigarette smoking	0.883	0.232	0.207	3.810	0.000

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B.

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ISSN: 1476-511X

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