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Table 3 Genotypes of the rs2072183 SNP and serum lipid levels between the Mulao and Han populations

From: Association of rs2072183 SNP and serum lipid levels in the Mulao and Han populations

Genotype

n

TC (mmol/L)

TG (mmol/L)

HDL-C (mmol/L)

LDL-C (mmol/L)

ApoAI (g/L)

ApoB (g/L)

ApoAI/ApoB

Han

        

CC

290

4.90 ± 0.97

1.07(0.88)

1.70 ± 0.41

2.74 ± 0.77

1.34 ± 0.26

0.82 ± 0.20

1.72 ± 0.52

CG

346

5.05 ± 1.20

1.12(0.87)

1.74 ± 0.64

2.96 ± 0.92

1.33 ± 0.27

0.86 ± 0.21

1.59 ± 0.46

GG

102

5.14 ± 1.09

0.95(0.99)

1.75 ± 0.44

3.04 ± 0.97

1.32 ± 0.23

0.89 ± 0.22

1.59 ± 0.53

F

–

1.874

1.491

1.059

5.418

0.200

3.430

4.303

P

–

0.154

0.474

0.347

0.005

0.819

0.033

0.014

CC

290

4.90 ± 0.97

1.07(0.88)

1.70 ± 0.41

2.74 ± 0.77

1.34 ± 0.26

0.82 ± 0.20

1.72 ± 0.52

CG/GG

448

5.07 ± 1.18

1.06(0.89)

1.74 ± 0.60

2.98 ± 0.93

1.32 ± 0.26

0.87 ± 0.21

1.60 ± 0.47

F

–

3.650

−0.972

2.080

10.845

0.397

6.741

8.067

P

–

0.056

0.331

0.150

0.001

0.529

0.010

0.005

Male

        

CC

100

5.06 ± 0.92

1.23(1.28)

1.61 ± 0.45

2.75 ± 0.77

1.36 ± 0.30

0.89 ± 0.20

1.59 ± 0.49

CG

138

5.35 ± 1.20

1.18(0.86)

1.73 ± 0.42

3.03 ± 0.86

1.38 ± 0.29

0.92 ± 0.21

1.57 ± 0.44

GG

36

5.39 ± 1.26

1.29(2.12)

1.56 ± 0.34

3.26 ± 0.92

1.24 ± 0.16

1.01 ± 0.23

1.28 ± 0.25

F

–

3.231

0.946

2.388

4.764

2.197

4.664

5.021

P

–

0.041

0.623

0.094

0.009

0.113

0.010

0.007

CC

100

5.01 ± 0.92

1.23(1.28)

1.61 ± 0.45

2.75 ± 0.77

1.36 ± 0.30

0.89 ± 0.20

1.59 ± 0.49

CG/GG

174

5.36 ± 1.20

1.22(0.92)

1.69 ± 0.41

3.08 ± 0.88

1.35 ± 0.27

0.94 ± 0.21

1.51 ± 0.42

F

–

6.460

−0.789

2.775

8.980

0.003

4.269

2.550

P

–

0.012

0.430

0.097

0.003

0.954

0.040

0.111

Female

        

CC

190

4.81 ± 0.98

1.04(0.78)

1.75 ± 0.38

2.73 ± 0.77

1.33 ± 0.24

0.79 ± 0.19

1.79 ± 0.52

CG

208

4.84 ± 1.68

0.97(0.80)

1.75 ± 0.75

2.91 ± 0.96

1.29 ± 0.26

0.83 ± 0.20

1.62 ± 0.45

GG

66

5.01 ± 1.02

0.85(0.82)

1.85 ± 0.45

2.92 ± 0.97

1.37 ± 0.25

0.82 ± 0.18

1.77 ± 0.56

F

–

0.383

2.241

0.913

1.799

2.368

1.676

5.916

P

–

0.682

0.326

0.402

0.167

0.095

0.188

0.003

CC

190

4.81 ± 0.98

1.04(0.78)

1.75 ± 0.38

2.73 ± 0.77

1.33 ± 0.24

0.79 ± 0.19

1.79 ± 0.52

CG/GG

274

4.89 ± 1.13

0.96(0.80)

1.78 ± 0.68

2.91 ± 0.96

1.30 ± 0.26

0.83 ± 0.20

1.65 ± 0.49

F

–

0.201

−1.025

0.380

3.527

1.285

2.910

6.656

P

–

0.654

0.305

0.538

0.061

0.257

0.089

0.010

Mulao

        

CC

343

5.08 ± 1.11

1.07(0.72)

1.76 ± 0.43

2.96 ± 0.87

1.35 ± 0.39

0.99 ± 0.56

1.60 ± 0.71

CG

280

5.10 ± 1.16

1.10(0.88)

1.75 ± 0.44

3.01 ± 0.93

1.32 ± 0.41

1.01 ± 0.60

1.56 ± 0.83

GG

64

4.90 ± 1.10

1.14(0.82)

1.75 ± 0.46

2.88 ± 0.77

1.33 ± 0.39

0.86 ± 0.27

1.63 ± 0.56

F

–

0.521

0.603

0.004

0.324

0.229

1.503

0.040

P

–

0.594

0.740

0.996

0.723

0.742

0.223

0.961

CC

343

5.08 ± 1.11

1.07(0.72)

1.76 ± 0.43

2.96 ± 0.87

1.35 ± 0.39

0.99 ± 0.56

1.60 ± 0.71

CG/GG

344

5.06 ± 1.15

1.10(0.86)

1.75 ± 0.44

2.99 ± 0.90

1.32 ± 0.40

0.98 ± 0.55

1.58 ± 0.79

F

–

0.112

−0.764

0.008

0.008

0.586

0.081

0.010

P

–

0.738

0.445

0.931

0.928

0.444

0.776

0.919

Male

        

CC

146

5.05 ± 1.04

1.17(0.96)

1.71 ± 0.45

2.85 ± 0.75

1.39 ± 0.38

1.09 ± 0.68

1.54 ± 0.66

CG

118

5.34 ± 0.97

1.09(1.05)

1.83 ± 0.43

3.08 ± 0.85

1.36 ± 0.46

1.06 ± 0.61

1.49 ± 0.67

GG

24

4.89 ± 1.20

1.39(1.26)

1.73 ± 0.51

2.80 ± 0.71

1.36 ± 0.40

0.90 ± 0.32

1.62 ± 0.60

F

–

4.185

0.775

2.964

3.065

0.073

0.836

0.614

P

–

0.016

0.679

0.053

0.038

0.930

0.435

0.542

CC

146

5.05 ± 1.04

1.17(0.96)

1.71 ± 0.45

2.85 ± 0.75

1.39 ± 0.38

1.09 ± 0.68

1.54 ± 0.66

CG/GG

142

5.27 ± 1.02

1.12(1.02)

1.82 ± 0.45

3.03 ± 0.84

1.36 ± 0.45

1.03 ± 0.57

1.51 ± 0.66

F

–

3.075

−0.259

4.875

3.186

0.140

0.414

0.185

P

–

0.081

0.796

0.028

0.075

0.709

0.521

0.668

Female

        

CC

197

5.09 ± 1.16

1.02(0.59)

1.80 ± 0.40

3.04 ± 0.94

1.32 ± 0.39

0.92 ± 0.43

1.63 ± 0.75

CG

162

4.92 ± 1.25

1.10(0.66)

1.68 ± 0.43

2.96 ± 0.98

1.29 ± 0.37

0.98 ± 0.59

1.62 ± 0.93

GG

40

4.91 ± 1.04

0.99(0.74)

1.76 ± 0.42

2.93 ± 0.80

1.30 ± 0.38

0.84 ± 0.24

1.64 ± 0.55

F

–

1.215

2.093

2.518

0.546

0.199

1.106

0.056

P

–

2.989

0.351

0.082

0.580

0.820

0.332

0.946

CC

197

5.09 ± 1.16

1.02(0.59)

1.80 ± 0.40

3.04 ± 0.94

1.32 ± 0.39

0.92 ± 0.43

1.63 ± 0.75

CG/GG

202

4.92 ± 1.22

1.09(0.68)

1.70 ± 0.43

2.95 ± 0.95

1.29 ± 0.37

0.95 ± 0.84

1.62 ± 0.87

F

–

2.247

−1.364

4.146

0.963

0.364

0.661

0.020

P

–

0.135

0.172

0.042

0.327

3.547

0.417

0.888

  1. TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B; ApoAI/ApoB, the ratio of apolipoprotein AI to apolipoprotein B. The value of TG was presented as median (interquartile range). The difference among the genotypes was determined by the Kruskal-Wallis test or the Wilcoxon-Mann–Whitney test.
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Lipids in Health and Disease

ISSN: 1476-511X