Association of gender, ABCA1 gene polymorphisms and lipid profile in Greek young nurses

Table 5 Blood lipid levels according to ABCA1 polymorphisms in women

*WOMEN (n = 360)*	Genotype	Median	IQR	P^†
*R219K*
*Total cholesterol (mg/dl)*	RR	200	[160 – 238]	0.64
	RK	193	[155 – 238]
	KK	204	[163 – 249]
*Triglycerides (mg/dl)*	RR	89	[57 – 152]	0.88
	RK	87	[61 – 159]
	KK	94	[70 – 134]
*HDL cholesterol (mg/dl)*	RR	66	[52 – 82]	0.84
	RK	65	[55 – 85]
	KK	66	[55 – 85]
*LDL cholesterol (mg/dl)*	RR	105	[79 – 127]	0.18
	RK	104	[70 – 126]
	KK	117	[93 – 141]
*Apo A1 (mg/dl)*	RR	145	[111 – 187]	0.16
	RK	155	[110 – 194]
	KK	164	[122 – 204]
*R1587K*
*Total cholesterol (mg/dl)*	RR	189	[145 – 231]	0.09
	RK	203	[172 – 240]
	KK	203	[163 – 224]
*Triglycerides (mg/dl)*	RR	87	[57 – 146]	0.61
	RK	96	[61 – 160]
	KK	81	[69 – 136]
*HDL cholesterol (mg/dl)*	RR	66	[51 – 82]	0.82
	RK	67	[55 – 84]
	KK	64	[52 – 86]
*LDL cholesterol (mg/dl)*	RR	100	[66 – 121]	0.0053
	RK	112	[85 – 132]
	KK	106	[83 – 133]
*Apo A1 (mg/dl)*	RR	152	[109 – 189]	0.59
	RK	155	[114 – 188]
	KK	153	[116 – 194]
*I883M*
*Total cholesterol (mg/dl)*	II	198	[156 – 237]	0.54
	IM	196	[160 – 238]
	MM	214	[181 – 273]
*Triglycerides (mg/dl)*	II	90	[61–155]	0.45
	IM	86	[58 – 148]
	MM	188	[73 – 274]
*HDL cholesterol (mg/dl)*	II	66	[52–82.5]	0.61
	IM	66	[53 – 83]
	MM	73	[60 – 111]
*LDL cholesterol (mg/dl)*	II	104	[74 – 125]	0.34
	IM	109	[83 – 132]
	MM	124	[66 – 134]
*Apo A1 (mg/dl)*	II	154	[111–189]	0.86
	IM	149	[110 – 188]
	MM	166	[110 – 226]

HDL: high density lipoprotein, LDL: low density lipoprotein, Apo A1: apolipoprotein A1. ^† P values among genotypes from Kruskal Wallis test performance.

ISSN: 1476-511X