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Table 1 Plasma parameters in the fed state of the Mgat2 -deficient mice

From: MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

 

ND

HFD

Parameter

Mgat2 +/+

Mgat2 +/−

Mgat2 −/−

Mgat2 +/+

Mgat2 +/−

Mgat2 −/−

Glucose (mg/dL)

132 ± 4

130 ± 3

135 ± 5

168 ± 6###

168 ± 5

151 ± 7

Insulin (ng/mL)

1.4 ± 0.2

1.7 ± 0.4

2.0 ± 1.0

35.8 ± 10.4##

14.6 ± 3.0*

5.7 ± 1.8*

Triglyceride (mg/dL)

114.5 ± 12.5

123.2 ± 12.7

90.5 ± 5.6

102.7 ± 6.5

119.3 ± 7.4

94.4 ± 7.9

Total cholesterol (mg/dL)

81 ± 5

89 ± 4

94 ± 7

196 ± 14###

137 ± 6***

118 ± 6***

NEFA (mEq/L)

0.45 ± 0.03

0.43 ± 0.04

0.36 ± 0.04

0.46 ± 0.02

0.45 ± 0.02

0.46 ± 0.03

  1. Data are expressed as mean ± SEM. n = 6–15 per group. *P < 0.05, ***P < 0.001 vs. HFD +/+. ##P < 0.01, ###P < 0.001 vs. ND +/+.