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Table 1 Plasma parameters in the fed state of the Mgat2 -deficient mice

From: MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

  ND HFD
Parameter Mgat2 +/+ Mgat2 +/− Mgat2 −/− Mgat2 +/+ Mgat2 +/− Mgat2 −/−
Glucose (mg/dL) 132 ± 4 130 ± 3 135 ± 5 168 ± 6### 168 ± 5 151 ± 7
Insulin (ng/mL) 1.4 ± 0.2 1.7 ± 0.4 2.0 ± 1.0 35.8 ± 10.4## 14.6 ± 3.0* 5.7 ± 1.8*
Triglyceride (mg/dL) 114.5 ± 12.5 123.2 ± 12.7 90.5 ± 5.6 102.7 ± 6.5 119.3 ± 7.4 94.4 ± 7.9
Total cholesterol (mg/dL) 81 ± 5 89 ± 4 94 ± 7 196 ± 14### 137 ± 6*** 118 ± 6***
NEFA (mEq/L) 0.45 ± 0.03 0.43 ± 0.04 0.36 ± 0.04 0.46 ± 0.02 0.45 ± 0.02 0.46 ± 0.03
  1. Data are expressed as mean ± SEM. n = 6–15 per group. *P < 0.05, ***P < 0.001 vs. HFD +/+. ##P < 0.01, ###P < 0.001 vs. ND +/+.