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Table 2 Oxidative stress and inflammatory markers in patients with different LDL levels

From: Imbalance in superoxide dismutase/thioredoxin reductase activities in hypercholesterolemic subjects: relationship with low density lipoprotein oxidation

  Groups (LDL-cholesterol levels)
  Low-LDL Intermediate-LDL High-LDL
  (<100 mg/dL) (100–160 mg/dL) (>160 mg/dL)
TBARS (nmol MDA/mL) 4.9+ 0.3b 5.1+ 0.2b 6.3+ 0.3a
  (2.5-8.5) (2.4-8.0) (4.0-13.3)
Protein carbonyl content 1.2+ 0.1b 1.4+ 0.1a 1.9+ 0.2a
(nmol/mg of protein) (0.2-2.9) (0.7-4.9) (0.5-6.7)
LDLox (mg/L) 0.27+ 0.06b 0.39+ 0.04b 0.73+ 0.06a
  (0.0-1.0) (0.0-1.7) (0.03-1.9)
LDLoxAB (mg/L) 10.3+ 2.1c 22.4+ 1.5b 32.1+ 1.4a
  (0.7-36.0) (0.8-46.4) (9.2-54.7)
hs-CRP (mg/L) 0.42+ 0.07b 0.81+ 0.16b 1.55+ 0.26a
  (0.1-1.2) (0.1-7.9) (0.1-7.9)
  1. Results are expressed as mean + SEM (minimum – maximum). N = 23–50, as shown in Table 1. a,b,c Values within the same line that do not share a common superscript letter are significantly different from each other (p < 0.05). TBARS = thiobarbituric acid reactive substances; MDA = malondialdehyde; LDLox = oxidized LDL; LDLoxAB = LDLox autoantibodies; hs-CRP = highly sensitive C-reactive protein.