Eicosapentaenoic acid-enriched phospholipid ameliorates insulin resistance and lipid metabolism in diet-induced-obese mice

Table 5 Serum parameters related to glucose metabolism and inflammation reaction in C57BL/6J mice fed experimental diets ^a

	CT	HF	SOY-PL	EPA-PL
Glucose, mmol/L	5.18 ± 0.72	7.55 ± 0.78^##	4.43 ± 0.34**	3.95 ± 0.29**
Insulin, ng/mL	2.24 ± 0.20	1.97 ± 0.38	1.77 ± 0.34	1.99 ± 0.11
NEFA, μmol/L	146.3 ± 9.3	173.8 ± 15.3^#	113.8 ± 17.3**	131.3 ± 13.3*
Leptin, ng/mL	1.09 ± 0.24	2.56 ± 0.94^#	2.37 ± 0.63	2.08 ± 0.42
Adiponectin, ng/mL	6.71 ± 0.49	8.22 ± 0.78^#	8.90 ± 0.56	9.71 ± 0.66*
TNF-α, pg/mL	33.2 ± 3.7	52.9 ± 9.6^##	42.1 ± 7.5	32.0 ± 6.2*
IL-6, pg/mL	20.5 ± 2.8	27.6 ± 3.1^#	29.1 ± 5.2	19.0 ± 2.2*

Note: ^a Data are presented as mean ± SEM; n = 7 mice per group. ^#P < 0.05, ^##P < 0.01, significant difference compared to the control group determined by Student’s t test. *P < 0.05, **P < 0.01, significant difference compared to the HF group determined by ANOVA (Tukey’s test).

ISSN: 1476-511X