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Table 5 Serum parameters related to glucose metabolism and inflammation reaction in C57BL/6J mice fed experimental diets a

From: Eicosapentaenoic acid-enriched phospholipid ameliorates insulin resistance and lipid metabolism in diet-induced-obese mice

  CT HF SOY-PL EPA-PL
Glucose, mmol/L 5.18 ± 0.72 7.55 ± 0.78## 4.43 ± 0.34** 3.95 ± 0.29**
Insulin, ng/mL 2.24 ± 0.20 1.97 ± 0.38 1.77 ± 0.34 1.99 ± 0.11
NEFA, μmol/L 146.3 ± 9.3 173.8 ± 15.3# 113.8 ± 17.3** 131.3 ± 13.3*
Leptin, ng/mL 1.09 ± 0.24 2.56 ± 0.94# 2.37 ± 0.63 2.08 ± 0.42
Adiponectin, ng/mL 6.71 ± 0.49 8.22 ± 0.78# 8.90 ± 0.56 9.71 ± 0.66*
TNF-α, pg/mL 33.2 ± 3.7 52.9 ± 9.6## 42.1 ± 7.5 32.0 ± 6.2*
IL-6, pg/mL 20.5 ± 2.8 27.6 ± 3.1# 29.1 ± 5.2 19.0 ± 2.2*
  1. Note: a Data are presented as mean ± SEM; n = 7 mice per group. #P < 0.05, ##P < 0.01, significant difference compared to the control group determined by Student’s t test. *P < 0.05, **P < 0.01, significant difference compared to the HF group determined by ANOVA (Tukey’s test).