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Table 3 Biochemical parameters of young and adult rats submitted to different diets

From: Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats

Biochemical parameters

Young

Adult

CT

FAT

FRU

CT

FAT

FRU

Fasting glucose (mmol/L)

5,87 ± 0,14

7,18 ± 0,13*

5,77 ± 0,11

5,84 ± 0,17

5,42 ± 0,63

7,37 ± 0,19*

Triglycerides (mmol/L)

0,39 ± 0,07

0,27 ± 0,03

0,34 ± 0,06

0,64 ± 0,06†

0,68 ± 0,06

1,02 ± 0,11*

Total cholesterol (mmol/L)

2,29 ± 0,24

2,11 ± 0,12

2,26 ± 0,09

1,81 ± 0,16

2,27 ± 0,11

2,97 ± 0,23*

HDL cholesterol (mmol/L)

1,52 ± 0,08

0,37 ± 0,01*

0,38 ± 0,03*

1,63 ± 0,06

1,44 ± 0,24

1,80 ± 0,07

ALT (U/I)

17,31 ± 1,32

24,96 ± 0,92*

30,09 ± 2,78*

18,15 ± 1,80

26,67 ± 3,02*

32,87 ± 1,25*

AST (U/I)

38,56 ± 4,33

72,80 ± 2,27*

87,15 ± 5,35*

30,01 ± 1,01

28,51 ± 2,06

63,43 ± 3,02*

Creatinine (μmol/L)

53,81 ± 5,33

53,44 ± 8,93

57,98 ± 8,13

72,24 ± 14,63

51,06 ± 5,36

52,85 ± 11,85

Urea (mmol/L)

4,33 ± 0,66

4,28 ± 0,56

4,45 ± 0,22

5,05 ± 0,32

5,85 ± 0,50

4,96 ± 0,28

Total protein (g/L)

69,53 ± 1,23

68,17 ± 2,95

45,98 ± 3,03*

67,59 ± 1,04

66,47 ± 1,23

68,19 ± 1,54

Albumin (μmol/L)

352,90 ± 8,27

342,10 ± 20,69

260,0 ± 13,68*

389,00 ± 4,57†

378,60 ± 7,97

373,50 ± 13,63

N

12

18

8

8

10

9

  1. * P <0.05 compared to the respective group that consumed the CT diet. † P <0.05 compared to the Young - CT group.
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Lipids in Health and Disease

ISSN: 1476-511X