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Table 1 Study group compositions and daily dosing scheme for borage and echium seed oils in the four groups of subjects

From: Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics

  Group 1 Group 2 Group 3 Group 4
No. of Subjects 6 9 11 11
(female) (3) (5) (6) (7)
Age (range) 22–46 18–54 19–58 22–64
No. of subjects withdrawn 1 1 1 2
Echium Oil Dose (g) 14 7 4 2
No. of daily capsules 14 7 4 2
ALA (g) 4.02 2.01 1.15 0.57
SDA (g) 1.75 0.875 0.5 0.25
GLA (g) 1.54 0.77 0.44 0.22
Borage Oil Dose (g) 0 3.9 5.2 5.2
No. of daily capsules 0 3 4 4
ALA (g) <0.01 <0.01 <0.01 <0.01
SDA (g) 0 0 0 0
GLA (g) 0 0.9 1.2 1.2
Total     
No. of daily capsules 14 10 8 6
ALA (g) 4.02 2.01 1.15 0.57
SDA (g) 1.75 0.875 0.5 0.25
GLA (g) 1.54 1.67 1.64 1.44
  1. The number of daily capsules, containing 1 g (EO) or 1.3 g (BO) oil per capsule, and the amount of ALA, SDA and GLA provided by the encapsulated echium and borage oils is shown for each dosing group. Recruitment into Group 1 was stopped after the interim analyses showed that the highest dose of EO was not required to prevent elevations of AA levels in circulating plasma.