Table 5 Changes seen in the survival, FR generated, and LXA ₄ , TNF-α and IL-6 secreted by PC-3 cells when supplemented with different doses of fatty acids for 48 hours

Control

100 ± 1.86

100 ± 2.09

100 ± 2.60

100 ± 0.07

100 ± 6.34

LA 50 μM

105.00 ± 1.81*

104.31 ± 6.33*

56.00 ± 6.61***

67.06 ± 6.11**

53.75 ± 6.67***

LA 150 μM

95.00 ± 4.62*

102.65 ± 6.77*

72.00 ± 4.00**

71.18 ± 4.58**

71.25 ± 3.97**

GLA 25 μM

88.61 ± 4.39*

68.49 ± 3.35**

187.49 ± 2.11***

158.71 ± 9.66***

137.00 ± 3.94**

GLA 50 μM

82.53 ± 3.72**

74.67 ± 2.34**

179.34 ± 0.79***

148.57 ± 8.14***

148.81 ± 4.64***

GLA 75 μM

67.74 ± 3.81***

58.97 ± 5.11***

200.20 ± 2.94***

174.32 ± 7.32***

259.95 ± 6.95***

AA 50 μM

80.35 ± 1.21**

55.81 ± 2.99***

108.90 ± 0.39*

100.66 ± 5.24

73.22 ± 0.91**

AA 100 μM

60.08 ± 4.04***

76.32 ± 3.80**

99.17 ± 1.07

98.22 ± 1.32

65.50 ± 1.28**

ALA 50 μM

93.14 ± 1.66*

112.27 ± 6.82*

56.41 ± 5.44***

57.14 ± 4.58***

75.00 ± 3.90**

ALA150μM

70.59 ± 1.51**

160.86 ± 7.10***

48.72 ± 6.92***

45.71 ± 7.70***

83.75 ± 6.54**

EPA 50 μM

83.36 ± 6.65**

90.84 ± 6.30*

88.50 ± 0.75*

97.77 ± 2.13

80.41 ± 3.29**

EPA 100 μM

77.83 ± 5.55**

76.98 ± 4.97**

89.54 ± 1.22*

101.33 ± 5.59

81.13 ± 1.00**

DHA 50 μM

88.94 ± 6.91*

80.99 ± 2.88**

81.43 ± 1.09**

67.64 ± 1.95**

69.14 ± 2.85**

DHA100μM

75.88 ± 3.55**

67.00 ± 6.24**

76.84 ± 0.69**

57.71 ± 2.78***

66.69 ± 1.60**